CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3764
Family Name Metabotropic glutamate receptor 5 Ligand 3-chloro-5-(2-methylquinolin-7-yl)benzonitrile Family
No. of Seeds 3 No. of Other Members 4
Family Centroid CFAMM00297510 Functional Category Investigative Drug
Superfamily Metabotropic glutamate receptor 5 Binder Superfamily 3
Class Class 2874

Cousin Family NamesSeedsMembers
Glutamate dehydrogenase inhibitor quinoline derivative Chloroq... 7 189
Histamine H1 receptor ligand tricyclic antidepressant Deslorat... 6 136
Acetylcholinesterase Inhibitor Tacrine Family 12 515
Sarcoplasmic/endoplasmic reticulum calcium ATPase inhibitor qu... 2 60
D(1B) dopamine receptor Ligand LE-300 Family 65 452
Lethal factor Inhibitor N,n'-bis(4-amino-2-methylquinolin-6-yl... 2 11
Potassium voltage-gated channel subfamily H member 2 Ligand 5-... 5 14
5-hydroxytryptamine receptor 2A Ligand 8-chloro-1,2,3,4-tetrah... 5 4
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 8-(3... 4 19
Acetylcholinesterase and Cholinesterase Inhibitor Huprine-tacr... 43 17
Metabotropic glutamate receptor 5 Ligand 2-methyl-6-(4-phenylb... 6 32
Cathepsin S Inhibitor 6-(3-(trifluoromethyl)phenyl)picolinonit... 7 2
Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor N... 6 10
Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor N... 1 3
Metabotropic glutamate receptor 5 Ligand 5-(2-methylquinolin-7... 4 3
Metabotropic glutamate receptor 5 Ligand 3-fluoro-5-(2-methylq... 3 2
Protein kinase C alpha type Inhibitor Dequalinium Analogue Family 1 10
Acetylcholinesterase and Cholinesterase Inhibitor Huprine-tacr... 62 27
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 3
Corticotropin-releasing factor receptor 1 ligand 3,7-dimethyl-... 3 4
Corticotropin-releasing factor receptor 1 ligand N-(cyclopropy... 2 2
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand 6-(2-... 1 2
Corticotropin-releasing factor receptor 1 ligand 2-(2,4-dichlo... 2 2
Potassium voltage-gated channel subfamily H member 2 ligand 1-... 1 0
(E,2S)-4-quinolin-2-ylbut-3-en-2-ol NP (s,e)-4-(quinolin-2-yl)... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00297506 DNC013365 Investigative Drug 7-(3-chlorophenyl)-2-methylquinoline
CFAMM00297503 DNC014348 Investigative Drug 5-Chloro-2-(2-methylquinolin-7-yl)benzonitrile
CFAMM00297510 DNC013359 Investigative Drug 3-chloro-5-(2-methylquinolin-7-yl)benzonitrile

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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