CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3765
Family Name Metabotropic glutamate receptor 5 Ligand (3-(2-methylquinolin-7-yl)phenyl)methanol Family
No. of Seeds 3 No. of Other Members 6
Family Centroid CFAMM00297516 Functional Category Investigative Drug
Superfamily Metabotropic glutamate receptor 5 and Acetylcholinesterase Binder Superfamily
Class Class 183

Cousin Family NamesSeedsMembers
Phospholipase A2 Inhibitor Quinacrine Family 13 95
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 53 741
Food vacuoles Inhibitor Mefloquine Family 2 25
Arachidonate 5-lipoxygenase-activating protein Inhibitor DG031... 3 206
Dihydroorotate dehydrogenase Inhibitor Brequinar Family 9 122
Dihydroorotate dehydrogenase Inhibitor Cinchoninic Acid Family 1 21
Cytochrome b Inhibitor 2-nonyl-4-hydroxyquinoline N-OXIDE Family 2 22
Acetylcholinesterase Inhibitor Velnacrine Family 2 29
Lethal factor Inhibitor 3-(2,5-dimethyl-1h-pyrrol-1-yl)benzoic... 2 44
Metabotropic glutamate receptor 5 Ligand 2-methyl-6-((3-methox... 3 9
D(1B) dopamine receptor and D(2) dopamine receptor Ligand Flut... 1 6
Metabotropic glutamate receptor 5 Ligand 3-methoxy-5-(2-methyl... 7 27
Metabotropic glutamate receptor 5 Ligand 3-hydroxy-5-(2-methyl... 2 1
Metabotropic glutamate receptor 5 Ligand 3-methoxy-5-(1,5-naph... 4 20
Metabotropic glutamate receptor 5 Ligand 2-phenylethynyl-5,6,7... 1 4
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 3 1
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-09Q7W... 7 3
Alpha-2C adrenergic receptor and Alpha-2A adrenergic receptor ... 5 8
DNA topoisomerase 2-alpha and DNA topoisomerase 2-beta inhibit... 2 7
3-methyl-2-(quinolin-2-ylmethyl)-2H-furan-5-one NP 4-methyl-5-... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00297518 CHEMBL231790 Bioactive SureCN4297852
CFAMM00297516 DNC013366 Investigative Drug (3-(2-methylquinolin-7-yl)phenyl)methanol
CFAMM00297515 DNC013367 Investigative Drug 7-(3-(methoxymethyl)phenyl)-2-methylquinoline

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27511 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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