CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3778
Family Name Tyrosinase Inhibitor 4-(6-hydroxynaphthalen-2-yl)benzene-1,3-diol Family
No. of Seeds 4 No. of Other Members 2
Family Centroid CFAMM00297632 Functional Category Investigative Drug with Human Metabolite
Superfamily Tyrosinase and Oestrogen receptor Binder Superfamily
Class Class 2231

Cousin Family NamesSeedsMembers
Cannabinoid receptor 1 Ligand Marinol Family 32 454
Fatty-acid amide hydrolase 1 Inhibitor Propofol Family 5 428
Estrogen receptor beta Ligand Conjugated Estrogens Family 12 210
Oestrogen receptor ligand steroid Estradiol Family 18 147
Oestrogen receptor ligand Dienestrol Family 35 440
Sphingosine kinase 2 Inhibitor Phenoxodiol Family 24 682
NAD-dependent protein deacetylase sirtuin-1 Inhibitor SRT501 F... 19 88
Multidrug resistance protein Inhibitor Curcumin I Family 19 278
Oxi4503 family 4 27
TS-071 family 8 36
Estrogen receptor beta Ligand 1-chloro-6-(4-hydroxyphenyl)-2-n... 12 23
Platelet-activating factor receptor Ligand L-652731 Family 5 116
Glucocorticoid receptor Ligand 1-methoxy-6-phenyl-6h-benzo[c]c... 2 22
Oestrogen receptor and Estrogen receptor beta Ligand 6-(4-hydr... 30 63
Abelson tyrosine-protein kinase 2 Inhibitor 3'',5''-dimethoxy-... 3 9
Oestrogen receptor and Estrogen receptor beta Ligand 1-bromo-6... 3 4
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 5 13
Arachidonate 15-lipoxygenase Inhibitor Hydrohalisulfate 1 Family 6 6
Tubulin beta chain Inhibitor Combretastatin Family 3 5
NAD(P)H dehydrogenase [quinone] 1 Inhibitor NSC-106547 Family 3 65
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 4-(1,... 3 31
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 4 37
Estradiol 17-beta-dehydrogenase 1 Inhibitor 3-(6-hydroxy-2-nap... 7 9
Indoleamine 2,3-dioxygenase 1 Inhibitor Naphthalene-1,4-diol F... 2 4
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 1 2
Tyrosinase Inhibitor Kazinol S Family 1 0
Tyrosinase Inhibitor 4-adamantyl Resorcinol Family 1 1
Vitamin D3 receptor ligand (3E,5E)-6-[3-[[3,4-bis(hydroxymethy... 2 4
Estrogen receptor beta and Estrogen receptor ligand (4Z)-2-flu... 2 0
Androgen receptor and Progesterone receptor ligand diarylpheno... 1 1
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 4 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 5-(2-... 3 0
Acenes Metabolite 2-Methyl-1,4-naphthalenediol bis(dihydrogen ... 2 2
[(E)-3-carboxy-2-(5-methyl-2-oxidophenyl)prop-2-enyl]-(2-pheny... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00297631 DNC013423 Investigative Drug 7-(3,5-dihydroxyphenyl)naphthalene-1,3-diol
CFAMM00297630 DNC013422 Investigative Drug 5-(6-hydroxynaphthalen-2-yl)benzene-1,3-diol
CFAMM00297633 DNC013421 Investigative Drug 5-(6-hydroxy-2-naphthyl)-1,2,3-benzenetriol
CFAMM00297632 DNC013420 Investigative Drug 4-(6-hydroxynaphthalen-2-yl)benzene-1,3-diol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45918 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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