CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3782
Family Name Tyrosinase Inhibitor 1-(3-phenoxypropyl)-4-(piperidin-1-yl)piperidine Family
No. of Seeds 2 No. of Other Members 13
Family Centroid CFAMM00297653 Functional Category Investigative Drug
Superfamily Tyrosinase and Histamine H3 receptor Binder Superfamily
Class Class 282

Cousin Family NamesSeedsMembers
Voltage-dependent T-type calcium channel subunit alpha-1I liga... 5 209
Noradrenergic re-uptake and Serotonin re-uptake inhibitor bicy... 6 375
Oestrogen receptor Ligand triphenyl ethylene stilbene derivati... 22 420
Histamine H1 receptor Ligand Doxepin Family 8 89
Serotonin re-uptake Inhibitor Fluoxetine Family 18 682
Alpha adrenergic receptor Ligand Phenoxybenzamine Family 4 63
Beta-1 adrenergic receptor Ligand Oxprenolol Family 3 27
Noradrenergic re-uptake Inhibitor Reboxetine Family 26 206
Beta-1 adrenergic receptor Ligand Nebivolol Family 5 22
Oestrogen receptor Ligand Lasofoxifene Family 19 152
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 4 35
Substance-P receptor Ligand Ezlopitant Family 10 207
Dapoxetine family 3 40
Squalene synthase Inhibitor (z)-3-[2-(9h-fluoren-2-yloxy)ethyl... 12 92
Potassium voltage-gated channel subfamily H member 2 and Sodiu... 33 83
Histamine H3 receptor Ligand A-331440 Family 6 7
Histamine H3 receptor Ligand UCL-2138 Family 23 172
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 5 11
Adenosine receptor A3 and Mu-type opioid receptor Ligand GBR-1... 80 110
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 7 22
Histamine H3 receptor and Sodium-dependent serotonin transport... 25 28
Histamine H3 receptor Ligand (r)-1-(2-methoxyphenethyl)-2-meth... 10 27
Histamine H3 receptor Ligand 4-isopropyl-2-(phenoxymethyl)morp... 4 10
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 11
Sodium-dependent dopamine transporter and Sodium-dependent nor... 6 2
Histamine H3 receptor Ligand 1-(3-(2-(3-methoxyphenoxy)ethoxy)... 3 9
Sodium-dependent serotonin transporter Inhibitor 4-(2-((dimeth... 3 1
Sodium-dependent noradrenaline transporter Inhibitor WAY-25680... 4 6
Leukotriene A-4 hydrolase Inhibitor (r/s)-2-((4-phenoxyphenoxy... 7 18
Squalene synthase Inhibitor 3-[7'-(methoxy)-napht-2'-yl]-quinu... 53 30
Sodium-dependent dopamine transporter and Sodium-dependent nor... 6 13
5-hydroxytryptamine receptor 7 Ligand (r)-8-phenyl-n,n-dipropy... 9 14
5-hydroxytryptamine receptor 2A Ligand C-(9h-xanthen-9-yl)-met... 3 5
Sigma non-opioid intracellular receptor 1 and 3-beta-hydroxyst... 15 11
Survival motor neuron protein and Lysine-specific demethylase ... 1 16
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 7 0
5-hydroxytryptamine receptor 2A and Potassium voltage-gated ch... 2 8
Histamine H3 receptor and Potassium voltage-gated channel subf... 1 4
Histamine H3 receptor ligand cyclohexyl-[4-(3-piperidin-1-ylpr... 4 1
Muscarinic acetylcholine receptor M3 ligand AGN-PC-005QPZ family 1 0
Histamine H3 receptor ligand SureCN6071181 family 2 1
Histamine H3 receptor and Sodium-dependent serotonin transport... 6 1
Sodium-dependent serotonin transporter and Histamine H3 recept... 7 0
Histamine H3 receptor ligand AGN-PC-01WABH family 1 1
Histamine H3 receptor and Sodium-dependent serotonin transport... 3 6
Sigma non-opioid intracellular receptor 1 ligand AGN-PC-073OMG... 3 0
Sigma non-opioid intracellular receptor 1 ligand 4-[[1-[(2-bro... 2 0
Neuronal acetylcholine receptor subunit alpha-10 ligand (2S)-2... 1 0
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 6
Sigma non-opioid intracellular receptor 1 ligand 1-(3-fluoropr... 2 0
Sigma non-opioid intracellular receptor 1 ligand SureCN7450653... 1 0
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 2 2
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 1 3
Sodium-dependent noradrenaline transporter and Sodium-dependen... 4 2
Sodium-dependent noradrenaline transporter and Sodium-dependen... 1 1
5-hydroxytryptamine receptor 2A ligand AC-165024 family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00297653 DNC013448 Investigative Drug 1-(3-phenoxypropyl)-4-(piperidin-1-yl)piperidine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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