CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3790
Family Name 3-hydroxy-3-methylglutaryl-coenzyme A reductase Inhibitor PF-3052334 Family
No. of Seeds 6 No. of Other Members 1
Family Centroid CFAMM00297829 Functional Category Investigative Drug
Superfamily 3-hydroxy-3-methylglutaryl-coenzyme A reductase Inhibitor Atorvastatin Superfamily
Class Class 327

Cousin Family NamesSeedsMembers
3-hydroxy-3-methylglutaryl-coenzyme A reductase Inhibitor Ator... 3 24
3-hydroxy-3-methylglutaryl-coenzyme A reductase Inhibitor Fluv... 6 53
3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor (3R,... 3 3


External ID

Functional Category

Molecule Name

CFAMM00297830 CHEMBL251188 Bioactive pyrazole, 3f
CFAMM00297828 CHEMBL400644 Bioactive pyrazole, 3gg
CFAMM00297827 CHEMBL400983 Bioactive pyrazole, 3q
CFAMM00297826 CHEMBL400982 Bioactive pyrazole, 3b
CFAMM00297832 CHEMBL250168 Bioactive (3R,5R)-7-[5-[(3S)-3-(3,4,4a,8a-tetrahydro-1H-isoquinolin-2-yl)piperidine-1-carbonyl]-2-(4-fluorophenyl)-4-propan-2-ylpyrazol-3-yl]-3,5-dihydroxyheptanoic acid
CFAMM00297829 DNC013467 Investigative Drug PF-3052334

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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