CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3794
Family Name Metabotropic glutamate receptor 5 Ligand 2-phenylethynyl-7,8-dihydro-6h-quinolin-5-one Family
No. of Seeds 1 No. of Other Members 2
Family Centroid CFAMM00297875 Functional Category Investigative Drug
Superfamily Metabotropic glutamate receptor 5 and Telomerase reverse transcriptase Binder Superfamily
Class Class 1284

Cousin Family NamesSeedsMembers
Cytochrome P450 11B1, mitochondrial Inhibitor Metyrapone Family 9 243
Neuromedin-K receptor Ligand SB222200 Family 17 235
Mitogen-activated protein kinase 14 Inhibitor Losmapimod Family 5 154
Poly [ADP-ribose] polymerase 1 Inhibitor 2-ethylquinoline-8-ca... 3 4
C-C chemokine receptor type 5 Ligand GT-1282 Family 21 14
Metabotropic glutamate receptor 5 Ligand 1-(3-(2-methylquinoli... 2 12
Metabotropic glutamate receptor 1 Ligand (e)-4,4-dimethyl-1-qu... 2 2
Metabotropic glutamate receptor 1 ligand [11C]JNJ-16567083 family 9 2
Metabotropic glutamate receptor 5 ligand AGN-PC-0A9SVV family 2 12
Motilin receptor ligand SureCN2768052 family 3 0
Metabotropic glutamate receptor 5 ligand 3-[2-(6-acetylpyridin... 1 2
Acetylcholinesterase inhibitor (9R)-11-amino-6,6,9-trimethyl-9... 1 0
3-amino-2,7,7-trimethyl-4-phenyl-6,8-dihydroquinolin-5-one NP ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00297875 DNC013476 Investigative Drug 2-phenylethynyl-7,8-dihydro-6H-quinolin-5-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27525 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543