CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3795
Family Name D(2) dopamine receptor and Sodium-dependent dopamine transporter Ligand Anolobine Family
No. of Seeds 6 No. of Other Members 10
Family Centroid CFAMM00297917 Functional Category Investigative Drug with Natural Product
Superfamily Glaziovine Superfamily
Class Class 66

Cousin Family NamesSeedsMembers
Noradrenergic re-uptake and Serotonin re-uptake inhibitor bicy... 6 375
Delta-type opioid receptor ligand opiate analog Codeine Family 15 184
u-type opioid receptor ligand opiate analog Buprenorphine Family 78 234
u-type opioid receptor ligand opiate opiate analog Oxymorphone... 22 105
Nicotinic acetylcholine receptor alpha subunit Ligand benzylis... 4 18
Sigma non-opioid intracellular receptor 1 ligand opiate Dextro... 9 33
D(1B) dopamine receptor Ligand Apomorphine Family 30 271
Neuronal acetylcholine receptor subunit alpha-2 Ligand Metocur... 18 169
Acetylcholinesterase Inhibitor Galantamine Family 4 49
Synaptic vesicular amine transporter Inhibitor Tetrabenazine F... 13 425
Glaziovine family 1 4
Melatonin receptor type 1A Ligand Agomelatine Family 12 164
D(3) dopamine receptor Ligand U-99194A Family 7 33
Squalene synthase Inhibitor (z)-3-[2-(9h-fluoren-2-yloxy)ethyl... 12 92
Potassium voltage-gated channel subfamily H member 2 and Sodiu... 33 83
M-phase inducer phosphatase 1 Inhibitor Naphthoquinone Analogs... 11 56
Peptide deformylase, mitochondrial Inhibitor Tylophorinidine F... 7 1
Tumor necrosis factor Inhibitor Y-39041 Family 9 51
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 24
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 6 131
D(2) dopamine receptor and D(1A) dopamine receptor Ligand 3-br... 2 1
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 41
Histamine H3 receptor and Sodium-dependent serotonin transport... 25 28
5-hydroxytryptamine receptor 2A and D(1A) dopamine receptor Li... 8 33
Squalene synthase Inhibitor 3-[7'-(methoxy)-napht-2'-yl]-quinu... 53 30
Cytochrome P450 3A4 Inhibitor 1,2-diacetoxylycorine Family 4 19
Mu-type opioid receptor Ligand Cyprodime Family 12 8
Tubulin beta chain Inhibitor Colchinol Family 3 109
D(2) dopamine receptor and D(1A) dopamine receptor Ligand 3-ch... 2 0
Kappa-type opioid receptor Ligand Morphinan Cyclic Imine Analo... 20 0
5-hydroxytryptamine receptor 1A ligand SureCN7035190 family 10 17
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 7 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 2 1
D(3) dopamine receptor ligand S 14297 family 1 2
Sigma non-opioid intracellular receptor 1 and D(2) dopamine re... 11 2
Sigma non-opioid intracellular receptor 1 ligand BAS 04057753 ... 5 8
Histamine H3 receptor and Sodium-dependent serotonin transport... 15 1
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 28
Carbonic anhydrase 14 and Carbonic anhydrase 9 inhibitor 1-(4-... 2 3
Melanin-concentrating hormone receptor 1 ligand 6-methoxy-4-[[... 2 15
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 2 0
Carbonic anhydrase 7 and Carbonic anhydrase 14 inhibitor 4-(6-... 7 8
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 6 0
7-dehydrocholesterol reductase inhibitor 2-[2-(4-chlorophenyl)... 2 3
Dipeptidyl peptidase 4 inhibitor SureCN8267584 family 1 1
Histamine H3 receptor and Sodium-dependent serotonin transport... 6 1
Sodium-dependent serotonin transporter and Histamine H3 recept... 7 0
Putative Bioactive 5-hexyl-2-[4-[(4-methylpiperazin-1-yl)methy... 2 0
Alpha-2A adrenergic receptor and Alpha-2C adrenergic receptor ... 2 26
Endothelin-1 receptor ligand 2-[(1R,3S)-1-(1,3-benzodioxol-5-y... 3 10
Integrin beta-3 and Integrin alpha-IIb inhibitor (3R)-3-(1,3-b... 4 2
Dipeptidyl peptidase 4 inhibitor SureCN664019 family 4 5
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 1 0
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 1 0
Benzazepines Metabolite N-Methylporphyroxine Family 1 2
Aporphines Metabolite 7-Hydroxydehydroglaucine Family 1 0
Aporphines Metabolite Dehydroaporheine Family 2 2
Putative NP ZINC12858318 Family 42 0
Putative NP ZINC12660125 Family 8 0
7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinoline NP ZINC33345333... 21 3
NP (z)-n-((4-(3,4-dimethoxyphenyl)tetrahydro-2h-pyran-4-yl)met... 3 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00297916 DNC013482 Investigative Drug NORSTEPHALAGINE
CFAMM00297915 DNC013480 Investigative Drug (S)-BULBOCAPNINE
CFAMM00297919 DNC013485 Investigative Drug PUKATEINE
CFAMM00297918 DNC013484 Investigative Drug ANONAINE
CFAMM00297917 DNC013483 Investigative Drug ANOLOBINE

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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