CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3803
Family Name Herpes simplex virus type 1 thymidine kinase Inhibitor N2-(3-trifluoromethylphenyl)guanine Family
No. of Seeds 1 No. of Other Members 2
Family Centroid CFAMM00297947 Functional Category Investigative Drug
Superfamily Herpes simplex virus type 1 thymidine kinase Inhibitor N2-(3-trifluoromethylphenyl)guanine Superfamily
Class Class 1651

Cousin Family NamesSeedsMembers
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand be... 4 301
Gamma-aminobutyric acid A receptor Ligand imidazopyridine deri... 5 644
5-hydroxytryptamine receptor Ligand Ramosetron Family 10 219
Prothrombin Inhibitor Dabigatran Family 7 182
cAMP-specific 3',5'-cyclic phosphodiesterase 4D Inhibitor Arof... 3 196
Translocator protein Inhibitor Emapunil Family 7 89
Dipeptidyl peptidase 4 Inhibitor SSR-162369 Family 8 27
GP-531 family 1 33
CC-486 family 7 103
Vascular endothelial growth factor receptor 2 Ligand XL999 Family 11 87
Adenosine receptor A1 and Adenosine receptor A2a Ligand 8-phen... 12 213
Adenosine receptor A1 and Adenosine receptor A2b Ligand PSB-11... 34 26
Kappa-type opioid receptor Ligand Brl 52974 Family 2 27
Herpes simplex virus type 1 thymidine kinase Inhibitor 9-(4-hy... 2 13
Serine/threonine-protein kinase B-raf Inhibitor 2-(benzylamino... 7 117
Integrin alpha-V and Integrin beta-3 Inhibitor SB-223245 Family 27 36
Adenosine receptor A3 Ligand 1-benzyl-1h-1,3,4b,9-tetraaza-flu... 19 165
Telomerase reverse transcriptase Inhibitor HOE-33258 Family 10 33
Melanocortin receptor Ligand Ac-his-dnal(2)-arg-trp-nh2 Family 112 67
Adenosine receptor A2b Ligand CVT-7124 Family 14 64
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Adenosine receptor A2a Ligand (e,e)-8-(4-phenylbutadien-1-yl)c... 11 43
Histamine H3 receptor Ligand 4-(2-(phenylamino)ethyl)-1h-imida... 5 16
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor SCH-577... 9 29
Prothrombin and Cationic trypsin inhibitor (2S)-N-[(2S)-1-(1H-... 4 15
Prothrombin inhibitor SureCN5854779 family 4 9
Mu-type opioid receptor and Mu-type opioid receptor ligand Sur... 5 10
Adenosine receptor A1 ligand SureCN10614388 family 5 1
Adenosine receptor A1 ligand 8-(2-amino-4-nitrophenyl)-1,3-dim... 1 0
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 2 1
Dipeptidyl peptidase 4 inhibitor Xanthine Analogue 4 family 1 4
Histamine H4 receptor ligand SureCN602132 family 1 8
Vascular endothelial growth factor receptor 2 ligand AC1LLCDM ... 1 2
Peroxisome proliferator-activated receptor gamma ligand 1-[(4-... 7 29
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 1
5-hydroxytryptamine receptor 4 ligand 6-chloro-N-[[1-(2-methyl... 10 19
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 4 2
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 6 2
Inositol monophosphatase 1 and 15-hydroxyprostaglandin dehydro... 1 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 18
Adenosine receptor A2a and Adenosine receptor A2b ligand SureC... 2 2
Tyrosine-protein kinase ITK/TSK and Receptor-type tyrosine-pro... 1 0
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 10 14
Histamine H3 receptor ligand SureCN2878688 family 8 1
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 5 4
Delta-type opioid receptor ligand ethyl N-[3-[(R)-[4-[ethyl(me... 2 6
Melanin-concentrating hormone receptor 1 ligand AGN-PC-075X3N ... 1 7
Vascular endothelial growth factor receptor 2 ligand (3Z)-3-[5... 4 11
Vascular endothelial growth factor receptor 2 ligand (3Z)-6-fl... 4 3
Platelet-derived growth factor receptor beta and Vascular endo... 5 12
Melanocortin receptor 4 ligand AGN-PC-076AMO family 17 8
5-hydroxytryptamine receptor 4 and 5-hydroxytryptamine recepto... 10 1
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 3 0
Thromboxane-A synthase inhibitor 6-chloro-3-(4-imidazol-1-ylbu... 12 21
Adenosine receptor A1 ligand 3-(4-Aminophenethyl)-8-(3-noradam... 1 0
Tyrosine-protein kinase SYK and Tyrosine-protein kinase ZAP-70... 3 0
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 2 0
Melanin-concentrating hormone receptor 1 ligand SureCN3834858 ... 2 1
Dipeptidyl peptidase 4 inhibitor SureCN5776796 family 1 0
Poly [ADP-ribose] polymerase 1 and Poly [ADP-ribose] polymeras... 4 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand SureC... 9 0
Cannabinoid receptor 2 ligand [(4S,4aR,8aS)-4-hydroxy-4-phenyl... 1 0
Corticotropin-releasing factor receptor 1 ligand AGN-PC-02ZKZ9... 9 12
C-X-C chemokine receptor type 3 ligand N-[(1R)-1-[3-(4-fluorop... 1 0
Retinal dehydrogenase 1 and Nuclear receptor ROR-gamma ligand ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00297947 DNC013527 Investigative Drug N2-(3-trifluoromethylphenyl)guanine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26413 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543