CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3811
Family Name Sodium-dependent dopamine transporter and Sodium-dependent noradrenaline transporter Inhibitor D-211B Family
No. of Seeds 5 No. of Other Members 2
Family Centroid CFAMM00298109 Functional Category Investigative Drug
Superfamily Biogenic amine receptor ligand Terfenadine Trihexyphenidyl Superfamily
Class Class 89

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Terfenadine Family 3 50
Alpha adrenergic receptor Ligand Pseudoephedrine Family 4 96
Muscarinic acetylcholine receptor M1 Ligand Trihexyphenidyl Fa... 14 199
Histamine H1 receptor ligand diphenylpiperidine analog Dipheny... 13 224
Histamine H1 receptor Ligand Chlophedianol Family 4 46
Mu-type opioid receptor ligand opiate Methadyl Acetate Family 5 9
Nicotinic acetylcholine receptor Ligand Benztropine Mesylate F... 10 20
Muscarinic acetylcholine receptor Ligand Umeclidinium Family 7 50
Choline kinase alpha Inhibitor Hemicholinium-3 Family 4 0
Peptide deformylase, mitochondrial Inhibitor Hydroxamates Family 6 17
Fibroblast growth factor receptor Ligand SU5403 Family 8 8
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor Sulfen... 5 13
Substance-P receptor Ligand L-733060 Family 19 71
Adenosine receptor A3 and Mu-type opioid receptor Ligand GBR-1... 80 110
Cytochrome P450 2D6 Inhibitor Bs 7840 Family 4 9
Potassium voltage-gated channel subfamily A member 5 Ligand 2-... 3 1
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 7 19
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 11 3
Potassium voltage-gated channel subfamily H member 2 Ligand [1... 2 23
Glutamate receptor ionotropic, NMDA 2B and Glutamate receptor ... 9 7
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-ri... 5 12
Sodium-dependent dopamine transporter and Sodium-dependent nor... 4 19
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 0
Substance-P receptor ligand (2S)-3-[[3,5-bis(trifluoromethyl)p... 1 4
Vesicular acetylcholine transporter inhibitor BENZOVESAMICOL f... 7 4
Sodium-dependent dopamine transporter and Sodium-dependent ser... 6 0
Vesicular acetylcholine transporter inhibitor 2-Naphthalenol, ... 3 2
Sodium-dependent dopamine transporter and Transporter inhibito... 2 0
Substance-P receptor ligand SureCN8415737 family 3 4
Sodium-dependent serotonin transporter and Sodium-dependent do... 3 0
Vesicular acetylcholine transporter inhibitor (1R,2R)-2-spiro[... 3 2
Substance-P receptor ligand AGN-PC-02K8GG family 1 1
Histamine H1 receptor and 5-hydroxytryptamine receptor 2A liga... 1 0
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00298104 DNC013563 Investigative Drug D-166A
CFAMM00298109 DNC013559 Investigative Drug D-211B
CFAMM00298107 DNC013560 Investigative Drug D-211A
CFAMM00298106 DNC013561 Investigative Drug D-257C
CFAMM00298105 DNC013562 Investigative Drug D-257A

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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