CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3817
Family Name Tyrosinase Inhibitor 1-hydroxy-3-phenylurea Family
No. of Seeds 2 No. of Other Members 10
Family Centroid CFAMM00298147 Functional Category Investigative Drug
Superfamily Tyrosinase Binder Superfamily
Class Class 2892

Cousin Family NamesSeedsMembers
Histone deacetylase 1 Inhibitor Vorinostat Family 26 138
Bifunctional epoxide hydrolase 2 Inhibitor 1-cyclohexyl-3-phen... 5 65
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-chloro-phenyl)... 5 50
5-hydroxytryptamine receptor 3A Ligand 1-(biphenyl-4-yl)-3-(4-... 20 67
Bifunctional epoxide hydrolase 2 Inhibitor 1-phenyl-3-(1-propi... 22 183
Acetylcholinesterase Inhibitor (3-hydroxy-2-methyl-phenyl)-tri... 4 25
Tyrosinase Inhibitor 1-hydroxy-3-(4-(trifluoromethyl)phenyl)ur... 2 3
Tyrosinase Inhibitor 1-hydroxy-3-(4-nitrophenyl)urea Family 2 2
DNA topoisomerase Inhibitor 6-(3-iodo-phenylamino)-1h-pyrimidi... 2 5
D(2) dopamine receptor and D(3) dopamine receptor ligand AGN-P... 5 5
D-amino-acid oxidase inhibitor 6-fluoro-3-hydroxy-7-methyl-1H-... 2 2
Retinal dehydrogenase 1 and Microtubule-associated protein tau... 1 0
Polyamine oxidase inhibitor AGN-PC-07C3XH family 1 2


External ID

Functional Category

Molecule Name

CFAMM00298148 DNC013588 Investigative Drug 3hydroxy-1-methyl-1-phenylurea
CFAMM00298147 DNC013586 Investigative Drug 1-hydroxy-3-phenylurea

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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