CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID382
Family Name Potassium voltage-gated channel subfamily KQT member 1 Ligand L-735,821 Family
No. of Seeds 19 No. of Other Members 186
Family Centroid CFAMM00189722 Functional Category Investigative Drug
Superfamily Potassium voltage-gated channel subfamily KQT member 1 Ligand L-735,821 Superfamily
Class Class 1566

Cousin Family NamesSeedsMembers
Benzodiazepine receptor ligand benzodiazepine derivative Fludi... 11 78
Benzodiazepine receptor ligand benzodiazepine derivative Oxaze... 4 0
Benzodiazepine receptor Ligand Clorazepate Family 2 3
Gamma-aminobutyric acid receptor ligand benzodiazepine derivat... 2 8
Benzodiazepine receptor ligand benzodiazepine derivative Fluni... 2 22
Glycine receptor subunit beta Ligand Gw 468816 Family 4 67
Motilin receptor Ligand GSK962040 Family 30 457
Serine/threonine-protein kinase mTOR Inhibitor CC-223 Family 12 135
Cholecystokinin receptor type A Ligand L-708474 Family 14 82
Cannabinoid receptor 1 Ligand 1-(bis(4-chlorophenyl)methyl)-3-... 4 44
Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 7 35
Phospholipase D1 Inhibitor Halopemide Family 17 111
Vasopressin V2 receptor Ligand VA-106483 Family 16 115
5-hydroxytryptamine receptor 3A Ligand 1-(biphenyl-4-yl)-3-(4-... 20 67
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 12 4
D(2) dopamine receptor Ligand PD-168077 Family 6 5
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Protein farnesyltransferase subunit beta and Protein farnesylt... 3 5
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-07ZBI0 family 2 16
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 14 8
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 7 5
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 15 12
Melanocortin receptor 4 and Melanocortin receptor 5 ligand N-[... 16 117
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 4 0
Coagulation factor X inhibitor 3-amino-4-chloro-N-[(1R)-2-[4-(... 1 1
P2X purinoceptor 7 inhibitor (4S)-N-[[2-chloro-3-(trifluoromet... 9 31
Vasopressin V2 receptor ligand [2-chloro-4-(prop-2-enylamino)p... 3 14
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 2 0
Substance-P receptor ligand (2S,4S)-2-N-[3-(diethylamino)propy... 2 7
D(3) dopamine receptor and D(2) dopamine receptor ligand 3-[4-... 4 23
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 8 1
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[(E... 24 11
Smoothened homolog inhibitor (8aS)-N-[2-(3-cyanophenyl)pyridin... 3 4
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 6 0
C-C chemokine receptor type 1 ligand SureCN3159355 family 7 9
D(3) dopamine receptor and D(2) dopamine receptor ligand RGH-1... 8 0
Melanocortin receptor 4 ligand N-[(2R)-3-(4-chlorophenyl)-1-[4... 11 9
Substance-P receptor and Substance-K receptor ligand AGN-PC-07... 5 2
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 6 13
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 4 0
Gastrin/cholecystokinin type B receptor ligand 2-[5-cyclohexyl... 2 1
Melanocortin receptor 4 and Cytochrome P450 3A4 ligand 2-amino... 52 12
Melanocortin receptor 4 ligand N-[(1S)-1-[2-[4-[(3S,4R)-4-(4-c... 26 13
C-C chemokine receptor type 1 ligand 3-[2-(carbamoylamino)phen... 2 1
Sodium channel protein type 9 subunit alpha ligand tert-butyl ... 2 30
C-C chemokine receptor type 2 ligand 2-amino-N-[2-[[(3R)-1-[(3... 2 4
Coagulation factor X inhibitor N-(4-chlorophenyl)-2-[[4-(2-oxo... 2 0
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 4 4
Oxytocin receptor ligand N-[1-[2-[[(2S)-1-amino-3-(3,4-dichlor... 1 0
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 4 0
Substance-P receptor ligand N-[[3,5-bis(trifluoromethyl)phenyl... 1 0
Gastrin/cholecystokinin type B receptor ligand AGN-PC-01ZDS6 f... 6 0
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 11 4
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 2 5
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 1 1
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 3
Coagulation factor VII and Prothrombin inhibitor 2-[(4-carbami... 1 2
Coagulation factor VII and Prothrombin inhibitor 2-[(4-carbami... 2 1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C and cAMP-speci... 1 0
Gastrin/cholecystokinin type B receptor ligand 2-[5-cyclohexyl... 1 1
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 1 0
E3 ubiquitin-protein ligase Mdm2 inhibitor SureCN5171589 family 10 0
Putative NP ZINC55466512 Family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00189810 CHEMBL2111920 Bioactive SureCN9842589
CFAMM00189755 CHEMBL1907852 Bioactive 4-chloro-N-[(3S)-5-(2-fluorophenyl)-1-methyl-2-oxo-3H-1,4-benzodiazepin-3-yl]benzamide
CFAMM00189675 CHEMBL342640 Bioactive SureCN9865997
CFAMM00189674 CHEMBL335951 Bioactive MS-8667
CFAMM00189706 CHEMBL40211 Bioactive SureCN9526186
CFAMM00189793 CHEMBL169438 Bioactive 4-chloro-N-[(3R)-1-methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepin-3-yl]benzamide
CFAMM00189773 CHEMBL168852 Bioactive SureCN9524675
CFAMM00189725 CHEMBL72300 Bioactive SureCN9525295
CFAMM00189705 CHEMBL72073 Bioactive SureCN9524671
CFAMM00189779 CHEMBL136608 Bioactive SureCN9842237
CFAMM00189737 CHEMBL1907661 Bioactive (E)-N-[(3S)-1-methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepin-3-yl]-3-phenylprop-2-enamide
CFAMM00189778 CHEMBL137066 Bioactive MS-8653
CFAMM00189818 CHEMBL169661 Bioactive SureCN9865023
CFAMM00189811 CHEMBL72428 Bioactive AGN-PC-000PNO
CFAMM00189722 DNC000858 Investigative Drug L-735,821

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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