CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3820
Family Name Tyrosinase Inhibitor 1-hydroxy-3-(4-(trifluoromethyl)phenyl)urea Family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00298172 Functional Category Investigative Drug
Superfamily Sodium channel Ligand Carbamazepine Superfamily
Class Class 106

Cousin Family NamesSeedsMembers
Mu-type opioid receptor Ligand Fentanyl Family 9 647
Sodium channel Ligand iminostilbene derivative (tricyclic stru... 2 46
D(2) dopamine receptor ligand diphenylbutylpiperidine derivati... 10 157
Motilin receptor Ligand GSK962040 Family 30 457
Serine/threonine-protein kinase mTOR Inhibitor CC-223 Family 12 135
Bifunctional epoxide hydrolase 2 Inhibitor 1-cyclohexyl-3-phen... 5 65
5-hydroxytryptamine receptor 5A Ligand N,4-dimethyl-3,4-dihydr... 8 51
Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ... 14 78
Progesterone receptor Ligand 2,2,4-trimethyl-6-phenyl-1,2-dihy... 5 82
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-chloro-phenyl)... 5 50
Androgen receptor Ligand YM-175735 Family 30 129
Kinesin-like protein KIF11 Inhibitor N-{4'-[(trifluoromethyl)s... 3 1
Kinesin-like protein KIF11 Inhibitor N-[4'-(trifluoromethyl)-4... 7 134
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 7 13
5-hydroxytryptamine receptor 3A Ligand 1-(biphenyl-4-yl)-3-(4-... 20 67
Bifunctional epoxide hydrolase 2 Inhibitor 1-phenyl-3-(1-propi... 22 183
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 5 18
5-hydroxytryptamine receptor 3B and 5-hydroxytryptamine recept... 4 24
Tyrosinase Inhibitor 1-hydroxy-3-phenylurea Family 2 10
Trypsin Inhibitor 1,3-di-p-tolyl-[1,3]diazetidine-2,4-dione Fa... 2 16
DNA topoisomerase Inhibitor 6-p-tolylamino-1h-pyrimidine-2,4-d... 3 17
DNA topoisomerase Inhibitor 6-(indan-5-ylamino)-1h-pyrimidine-... 2 0
DNA topoisomerase Inhibitor 6-(naphthalen-2-ylamino)-1h-pyrimi... 2 1
D(2) dopamine receptor and D(3) dopamine receptor ligand AGN-P... 5 5
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 3 1
Cathepsin K and Cathepsin L1 inhibitor 1-[(2S)-1-[[cyano(methy... 2 1
Melanin-concentrating hormone receptor 1 ligand 1-[2-[4-(3-cya... 3 2
Bifunctional epoxide hydrolase 2 inhibitor 1-(2,3,4-trifluorop... 2 2
Carbonic anhydrase 1 and Carbonic anhydrase 2 inhibitor 1-(3,5... 2 0
Histamine H3 receptor and Histamine receptor H3 ligand 1-cyclo... 3 4
C-X-C chemokine receptor type 3 and Muscarinic acetylcholine r... 1 0
C-C chemokine receptor type 3 ligand AGN-PC-073RIP family 2 4
D(3) dopamine receptor and D(2) dopamine receptor ligand 1-[2-... 3 1
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 3 0
D(3) dopamine receptor and D(2) dopamine receptor ligand 1-(3-... 1 0
D-amino-acid oxidase inhibitor 6-fluoro-3-hydroxy-7-methyl-1H-... 2 2
Sterol O-acyltransferase 1 inhibitor SureCN7565101 family 2 10
Acyl-CoA:cholesterol acyltransferase inhibitor 1-[2,6-di(propa... 7 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00298174 CHEMBL1569926 Bioactive FLUOMETURON
CFAMM00298172 DNC013590 Investigative Drug 1-hydroxy-3-(4-(trifluoromethyl)phenyl)urea

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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