CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID384
Family Name Suppressor of tumorigenicity 14 protein and Prothrombin Inhibitor 2-nas-phe(3-am)-4-(2-guanidinoethyl)piperidine Family
No. of Seeds 4 No. of Other Members 126
Family Centroid CFAMM00190163 Functional Category Investigative Drug
Superfamily Suppressor of tumorigenicity 14 protein and Trypsin Binder Superfamily
Class Class 1568

Cousin Family NamesSeedsMembers
Cathepsin K Inhibitor Odanacatib Family 33 84
Upamostat family 1 13
Carbonic anhydrase 2 Inhibitor N-benzyl-4-sulfamoyl-benzamide ... 12 44
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 2-valp... 8 5
Suppressor of tumorigenicity 14 protein Inhibitor 3-tapap Family 15 39
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 44 28
Trypsin Inhibitor Benzamidrazone Analogue Family 16 6
Coagulation factor X inhibitor (6S,8aS)-2-benzhydrylsulfonyl-N... 5 5
Plasminogen and Plasma kallikrein inhibitor CHEMBL2016864 family 9 16
Prothrombin and Cationic trypsin inhibitor 2-[butyl-[(2S)-4-[[... 7 32
Cathepsin L1 and Cathepsin B inhibitor (2S)-3-methyl-N-[(2S)-4... 7 24
Neutrophil collagenase and Stromelysin-1 inhibitor AGN-PC-044L... 6 7
Coagulation factor X and Trypsin-1 inhibitor SureCN6161266 family 2 28
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 1 4
B1 bradykinin receptor ligand SureCN13936521 family 19 4
Kappa-type opioid receptor and Delta-type opioid receptor liga... 9 0
Cathepsin K and Cathepsin L1 inhibitor N-[1-(cyanomethylcarbam... 2 0
B1 bradykinin receptor ligand N-[2-[4-(4,5-dihydro-1H-imidazol... 2 0
Suppressor of tumorigenicity 14 protein and Plasminogen inhibi... 10 15
B1 bradykinin receptor and B2 bradykinin receptor ligand SureC... 3 0
72 kDa type IV collagenase and Stromelysin-1 inhibitor (2R)-N-... 7 1
Prothrombin and Cationic trypsin inhibitor (2S)-3-(5-carbamimi... 2 0
Trypsin-1 inhibitor (2R)-1-[(2S)-3-(4-carbamimidoylphenyl)-2-[... 1 0
Growth hormone secretagogue receptor type 1 ligand [(3S)-3-ami... 2 6
Prothrombin inhibitor (2S)-3-[4-[amino(hydrazinyl)methyl]pheny... 1 0
Suppressor of tumorigenicity 14 protein and Prothrombin inhibi... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00190122 DNC001366 Investigative Drug SR 120819A
CFAMM00190163 DNC006759 Investigative Drug 2-nas-phe(3-am)-4-(2-guanidinoethyl)piperidine
CFAMM00190132 DNC000863 Investigative Drug LB30057
CFAMM00190171 DNC004439 Investigative Drug RPR-118071

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27627 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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