CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3878
Family Name Fatty-acid amide hydrolase 1 Inhibitor 3-(ethoxycarbonyl)phenylboronic Acid Family
No. of Seeds 2 No. of Other Members 69
Family Centroid CFAMM00299464 Functional Category Investigative Drug with Human Metabolite & Natural Product
Superfamily Glutamate carboxypeptidase 2 and Beta-lactamase Binder Superfamily
Class Class 1688

Cousin Family NamesSeedsMembers
Retinoid X receptor Ligand Bexarotene Family 7 492
Sodium channel protein type 5 subunit alpha Ligand Hexylcaine ... 4 94
Cyclooxygenase Inhibitor Flurbiprofen Family 18 294
DNA topoisomerase 1 Inhibitor Beta-lapachone Family 3 66
Carbonic anhydrase 2 Inhibitor 4-(hydroxymercury)benzoic Acid ... 7 97
Nicotinate-nucleotide pyrophosphorylase [carboxylating] Inhibi... 2 119
Beta-lactamase Inhibitor 4-carboxyphenylboronic Acid Family 1 1
Carbonic anhydrase 2 Inhibitor 1-pentenyl-4-(aminosulfonyl)ben... 8 34
Carbonic anhydrase 2 Inhibitor Sodium 2,3,5,6-tetrafluorobenzo... 1 0
C-X-C chemokine receptor type 1 and C-X-C chemokine receptor t... 2 53
Liver carboxylesterase 1 Inhibitor 1,2-bis(2,5-difluorophenyl)... 12 10
Liver carboxylesterase 1 Inhibitor 2,2-dimethoxy-1,2-diphenyl-... 1 16
Glutamate carboxypeptidase 2 Inhibitor 2-(3-carboxybenzyl)succ... 2 7
Glutamate carboxypeptidase 2 Inhibitor 3-(2-carboxy-6-mercapto... 9 4
Gamma-secretase subunit APH-1B and Presenilin-1 Inhibitor (5r,... 3 9
Neutrophil elastase Inhibitor 3,4-dichloroisocoumarin Family 1 5
Protein kinase C delta type and Protein kinase C alpha type In... 4 105
Cellular tumor antigen p53 and Thyrotropin receptor ligand CHE... 1 19
RAC-alpha serine/threonine-protein kinase inhibitor CHEMBL4754... 2 17
Arachidonate 15-lipoxygenase inhibitor SureCN9469035 family 6 40
Sodium-dependent dopamine transporter and Sodium-dependent ser... 1 10
DNA-(apurinic or apyrimidinic site) lyase and Retinal dehydrog... 1 18
Beta-lactamase inhibitor CHEMBL1358094 family 1 10
Aromatase inhibitor [(8R,9S,10R,13S,14S)-10,13-dimethyl-17-oxo... 2 10
Monoglyceride lipase inhibitor oxan-2-ylmethyl (E)-3-(4-phenyl... 1 2
Hydroxycarboxylic acid receptor 2 and Hydroxycarboxylic acid r... 3 0
Sodium-dependent dopamine transporter and Sodium-dependent nor... 1 0
Thromboxane A2 receptor ligand (Z)-7-[(4S,5R)-2,2-dimethyl-4-p... 2 9
Microtubule-associated protein tau and Putative fructose-1,6-b... 1 1
Benzyloxycarbonyls Metabolite Benzyl acetate Family 5 53
Epoxides Metabolite Phenylmethylglycidic ester Family 2 17
Aromatic Homomonocyclic Compounds Metabolite Dimethylbenzyl ca... 2 11
Phenylpropenes Metabolite alpha-Amylcinnamyl acetate Family 3 3
Benzyloxycarbonyls Metabolite Benzyl acetoacetate Family 1 6
[(1S,2S,5R)-2-hydroxy-2-methyl-5-prop-1-en-2-ylcyclohexyl] ben... 1 2
3-methyl-1-oxo-4H-isochromene-3-carboxylate NP Methyl 3-methyl... 4 1
NP 7-oxocyclohepta-1,3,5-trien-1-yl 4-chlorobenzoate Family 3 0
4-hydroxy-2-(4-methoxycarbonylphenyl)-4-methyl-6-oxocyclohexan... 15 2
3-(4-hydroxy-6-methyl-2-oxopyran-3-yl)-3H-2-benzofuran-1-one N... 2 2
carboxylate NP ZINC04026424 Family 3 7
(4,5-dioxooxolan-3-ylidene)-phenylmethanolate NP Agn-pc-03fjc2... 1 0
methylbenzoate NP 7-oxocyclohepta-1,3,5-trien-1-yl 3-methylben... 2 1
[(3S,4R)-4-benzoyloxythiolan-3-yl]azanium NP ZINC04061904 Family 1 1
ethoxy-[6-[ethoxy(oxido)methylidene]-3,7-dioxo-1,5-dihydro-s-i... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00299464 DNC013835 Investigative Drug 3-(ethoxycarbonyl)phenylboronic acid
CFAMM00299476 DNC014821 Investigative Drug BENZYL BENZOATE

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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