CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3888
Family Name Metabotropic glutamate receptor 1 Ligand 4-(cyclohexyloxy)quinazoline Family
No. of Seeds 1 No. of Other Members 4
Family Centroid CFAMM00299716 Functional Category Investigative Drug
Superfamily Angiopoietin-1 receptor and Tyrosine-protein kinase Lck Binder Superfamily
Class Class 685

Cousin Family NamesSeedsMembers
Peptide deformylase, mitochondrial Inhibitor Trimetrexate Family 4 311
Epidermal growth factor receptor Ligand Gefitinib Family 26 600
Receptor tyrosine-protein kinase erbB-2 Inhibitor CP-724714 Fa... 4 180
Vascular endothelial growth factor receptor 2 Ligand Cediranib... 8 38
SB1518 family 7 103
Tyrosine kinase Inhibitor PKI166 Family 17 198
Peptide deformylase, mitochondrial Inhibitor 5-(4-methoxypheno... 5 61
Angiopoietin-1 receptor and Tyrosine-protein kinase Lck Inhibi... 3 64
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 4 Inhibi... 19 48
Melanin-concentrating hormone receptor 1 Ligand ADS-102891 Family 6 51
Epidermal growth factor receptor Ligand 4-(5-bromoindole-3-yl)... 6 15
Reverse transcriptase Inhibitor UK-129485 Family 23 221
Sodium channel protein type 5 subunit alpha Ligand Enecadin Fa... 1 11
Metabotropic glutamate receptor 5 Ligand 4-(3-bromophenoxy)-6-... 1 0
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 6 35
Cathepsin S and Cathepsin K inhibitor AGN-PC-088VBO family 3 11
Angiopoietin-1 receptor and Aurora kinase B ligand SureCN12658... 3 19
Survival motor neuron protein inhibitor CHEMBL1307497 family 1 2
D(2) dopamine receptor and Alpha-1B adrenergic receptor ligand... 2 8
Prelamin-A/C and Nuclear receptor ROR-gamma ligand CHEMBL13704... 1 7
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 6 13
Methionine--tRNA ligase inhibitor 2-[3-[(2-ethoxy-5-iodo-3-met... 9 32
Prostaglandin D2 receptor ligand 2-[3-[2-methoxy-6-[2-(4-metho... 4 12
Adenosine receptor A3 ligand AGN-PC-08WSLM family 5 22
Insulin-like growth factor 1 receptor ligand 3qqu family 2 12
Xanthine dehydrogenase/oxidase inhibitor 4-[[4-(2-aminopyrimid... 3 16
Transient receptor potential cation channel subfamily V member... 2 4
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 2
Cathepsin K and Cathepsin S inhibitor SureCN4135077 family 2 0
Transient receptor potential cation channel subfamily V member... 2 0
Dihydrofolate reductase inhibitor AGN-PC-001U7R family 3 0
Vascular endothelial growth factor receptor 2 ligand pyrimidin... 2 2
Epidermal growth factor receptor ligand 4-Anilinoquinazoline d... 2 0
Corticotropin-releasing factor receptor 1 ligand N-(dicyclopro... 3 35


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00299716 DNC013878 Investigative Drug 4-(cyclohexyloxy)quinazoline

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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