CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3911
Family Name Fatty-acid amide hydrolase 1 Inhibitor 7-phenyl-1-(thiazol-2-yl)-heptan-1-one Family
No. of Seeds 4 No. of Other Members 5
Family Centroid CFAMM00300078 Functional Category Investigative Drug
Superfamily Fatty-acid amide hydrolase 1 Inhibitor 7-phenyl-1-(thiazol-2-yl)-heptan-1-one Superfamily
Class Class 2925

Cousin Family NamesSeedsMembers
Tubulin beta chain Inhibitor DOLASTATIN-10 Family 4 93
Coagulation factor X Inhibitor Phso2-gly-(me-gly)-arg-(2-thiaz... 32 62
Prothrombin inhibitor (3R,6R,8aS)-N-[5-(diaminomethylideneamin... 4 1
Prothrombin inhibitor (6S,8aS)-N-[5-(diaminomethylideneamino)-... 12 10
Histamine H1 receptor and Muscarinic acetylcholine receptor M1... 4 2
Prothrombin inhibitor N-[(2S)-3-[(3S)-1-carbamimidoylpiperidin... 4 10
Prolyl endopeptidase inhibitor 4-phenyl-1-[(2S)-2-[(2S)-2-(1,3... 1 0
Coagulation factor XI and Prothrombin inhibitor alpha-ketothia... 5 2
Prothrombin inhibitor (2S)-N-[(4-carbamimidoyl-1,3-thiazol-2-y... 3 2
Cationic trypsin and Prothrombin inhibitor benzyl N-[(2R)-1-[(... 2 6
Prothrombin and Cationic trypsin inhibitor (2S)-1-[(2R)-2-amin... 1 0
Coagulation factor X and Prothrombin inhibitor 2-[(3S)-3-benzy... 7 0
Prolyl endopeptidase inhibitor [(2S)-1-[(2S)-1-phenylmethoxypy... 2 0
Coagulation factor X and Prothrombin inhibitor SureCN7377461 f... 4 0
Prothrombin and Trypsin-1 inhibitor 2-[(2S)-4-benzyl-2-(naphth... 1 0
Metabotropic glutamate receptor 5 ligand 2-Phenylethynyl-thiaz... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00300077 CHEMBL255409 Bioactive [(2S)-1-[(2S)-1-(3-phenylpropyl)pyrrolidine-2-carbonyl]pyrrolidin-2-yl]-(1,3-thiazol-2-yl)methanone
CFAMM00300073 CHEMBL436620 Bioactive 4-phenyl-1-[(2S)-2-[(2R)-2-(1,3-thiazole-2-carbonyl)pyrrolidine-1-carbonyl]pyrrolidin-1-yl]butan-1-one
CFAMM00300072 CHEMBL168863 Bioactive SureCN8938620
CFAMM00300078 DNC014001 Investigative Drug 7-Phenyl-1-(thiazol-2-yl)-heptan-1-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27676 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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