CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID392
Family Name Dihydroorotate dehydrogenase Inhibitor LY214352 Family
No. of Seeds 2 No. of Other Members 17
Family Centroid CFAMM00190346 Functional Category Investigative Drug
Superfamily Dihydroorotate dehydrogenase Inhibitor LY214352 Superfamily
Class Class 1004

Cousin Family NamesSeedsMembers
Beta adrenergic receptor ligand monosubstituted indole derivat... 14 475
DNA Binder Primaquine Family 3 245
Histamine N-methyltransferase inhibitor aminoquinoline Amodiaq... 8 23
Phospholipase A2 Inhibitor Quinacrine Family 13 95
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 53 741
Amyloid beta A4 protein Inhibitor Florbetapir F-18 Family 8 265
Arachidonate 5-lipoxygenase Inhibitor MK-591 Family 9 161
5-hydroxytryptamine receptor 1A and D(3) dopamine receptor Lig... 9 115
Platelet-derived growth factor receptor alpha and Platelet-der... 2 9
Platelet-derived growth factor receptor alpha and Platelet-der... 2 14
5-hydroxytryptamine receptor 2A Ligand [2-(6-methoxy-indol-1-y... 2 10
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 4 35
Kappa-type opioid receptor Ligand Clioquinol Family 2 3
Metabotropic glutamate receptor 5 Ligand 3-methoxy-5-(2-methyl... 7 27
Metabotropic glutamate receptor 5 Ligand 3-methoxy-5-(1,5-naph... 4 20
Cannabinoid receptor 1 Ligand 1-(2-morpholinoethyl)-1h-indol-3... 8 46
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 22 57
Corticotropin-releasing factor receptor 1 ligand AGN-PC-074YQD... 1 5
Neuropeptide Y receptor type 1 ligand SureCN7959923 family 1 6
5-hydroxytryptamine receptor 2A and Alpha-1A adrenergic recept... 4 1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 3 1
Glucagon receptor and Mitogen-activated protein kinase 14 liga... 6 5
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 11 4
D(2) dopamine receptor ligand 129722-25-4 family 2 2
Somatostatin receptor type 2 ligand SureCN4317006 family 10 1
Cannabinoid receptor 1 ligand SureCN5355779 family 16 8
Prostaglandin D2 receptor 2 ligand 2-[3-(4-chlorophenoxy)-5-fl... 3 3
Lysosomal Pro-X carboxypeptidase inhibitor 1-(4-chloropyridin-... 6 1
5-hydroxytryptamine receptor 4 and 5-hydroxytryptamine recepto... 5 14
5-hydroxytryptamine receptor 4 and 5-hydroxytryptamine recepto... 6 4
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN4... 9 2
Sodium-dependent serotonin transporter and Sodium-dependent no... 3 8
Sigma non-opioid intracellular receptor 1 ligand 1'-[4-[1-(4-f... 2 0
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor 3-(2,3-... 2 0
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 23 5
D(4) dopamine receptor ligand AGN-PC-00FE9S family 1 6
Histidine-rich protein PFHRP-II inhibitor AGN-PC-075SYG family 1 0
NP 3-(6-chloro-1h-indol-1-yl)-1-(6,7-dimethoxy-3,4-dihydroisoq... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00190346 DNC000899 Investigative Drug LY214352
CFAMM00190336 DNC003963 Investigative Drug 1-Benzyl-7-chloro-4-hexyloxy-quinolinium

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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