CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3933
Family Name Corticosteroid 11-beta-dehydrogenase isozyme 1 Inhibitor PF-915275 Family
No. of Seeds 8 No. of Other Members 14
Family Centroid CFAMM00300256 Functional Category Investigative Drug
Superfamily Corticosteroid 11-beta-dehydrogenase isozyme 1 Inhibitor PF-915275 Superfamily
Class Class 122

Cousin Family NamesSeedsMembers
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-amin... 2 30
Plasminogen and Urokinase-type plasminogen activator Inhibitor... 3 26
Corticosteroid 11-beta-dehydrogenase isozyme 1 Inhibitor 2-(4-... 8 25
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 27
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 4 1
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor 4-[2-(... 2 6
Bombesin receptor subtype-3 and Nuclear receptor subfamily 1 g... 12 11
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 4-(4-... 1 1


External ID

Functional Category

Molecule Name

CFAMM00300250 CHEMBL2377209 Bioactive 4-(4-cyanophenyl)-N-quinolin-2-ylbenzenesulfonamide
CFAMM00300249 CHEMBL489857 Bioactive AGN-PC-00JLYM
CFAMM00300248 CHEMBL497105 Bioactive AGN-PC-071J7B
CFAMM00300261 CHEMBL495840 Bioactive AGN-PC-071J7C
CFAMM00300252 CHEMBL526098 Bioactive SureCN12640446
CFAMM00300259 CHEMBL495842 Bioactive AGN-PC-071J7D
CFAMM00300258 CHEMBL496082 Bioactive AGN-PC-071J7A
CFAMM00300256 DNC014069 Investigative Drug PF-915275

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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