CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3945
Family Name Fatty-acid amide hydrolase 1 Inhibitor 3-(4,5-dihydrooxazol-2-yl)phenyl Propylcarbamate Family
No. of Seeds 6 No. of Other Members 11
Family Centroid CFAMM00300353 Functional Category Investigative Drug
Superfamily Fatty-acid amide hydrolase 1 Inhibitor 3-(4,5-dihydrooxazol-2-yl)phenyl Propylcarbamate Superfamily
Class Class 184

Cousin Family NamesSeedsMembers
Acetylcholinesterase Inhibitor Rivastigmine Family 2 59
Serine/threonine-protein kinase PLK1 Inhibitor On Fa... 16 138
Melatonin receptor type 1A Ligand Agomelatine Family 12 164
Cannabinoid receptor 1 Ligand N-(4-methoxyphenethyl)oleamide F... 10 36
Fatty-acid amide hydrolase 1 Inhibitor N-butylcarbamic Acid Bi... 9 31
Fatty-acid amide hydrolase 1 Inhibitor 3-(trifluoromethyl)phen... 3 0
Fatty-acid amide hydrolase 1 Inhibitor 8-phenyloctylcarbamic A... 12 1
Fatty-acid amide hydrolase 1 Inhibitor Adamant-1-ylcarbamic Ac... 1 0
Cathepsin K inhibitor [1-(3-methoxyphenyl)-2-methylpropan-2-yl... 2 10
Fatty-acid amide hydrolase 1 and Monoglyceride lipase inhibito... 1 0


External ID

Functional Category

Molecule Name

CFAMM00300363 CHEMBL2396702 Bioactive [3-(4,5-dihydro-1,3-oxazol-2-yl)phenyl] N-(5-fluoropentyl)carbamate
CFAMM00300348 CHEMBL572891 Bioactive AGN-PC-073BAZ
CFAMM00300362 CHEMBL2314112 Bioactive [3-(4,5-dihydro-1,3-oxazol-2-yl)phenyl] N-hexylcarbamate
CFAMM00300347 CHEMBL575860 Bioactive methyl (4S)-2-[3-(cyclohexylcarbamoyloxy)phenyl]-4,5-dihydro-1,3-oxazole-4-carboxylate
CFAMM00300360 CHEMBL572681 Bioactive [3-[(5S)-5-methyl-4,5-dihydro-1,3-oxazol-2-yl]phenyl] N-cyclohexylcarbamate
CFAMM00300353 DNC014112 Investigative Drug 3-(4,5-Dihydrooxazol-2-yl)phenyl propylcarbamate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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