CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3957
Family Name Prostaglandin G/H synthase 2 Inhibitor Neolignan 9-nor-7,8-dehydro-isolicarin B Family
No. of Seeds 1 No. of Other Members 7
Family Centroid CFAMM00300457 Functional Category Investigative Drug with Human Metabolite & Natural Product
Superfamily Prostaglandin G/H synthase 2 and cAMP-specific 3',5'-cyclic phosphodiesterase 4A Binder Superfamily
Class Class 543

Cousin Family NamesSeedsMembers
Heat shock protein 90, putative Inhibitor Cromoglicate Family 14 2827
DNA Binder Methoxsalen Family 10 1638
D-alanyl-D-alanine carboxypeptidase Inhibitor B-lactams Family 59 1364
Aldehyde oxidase Inhibitor Isovanillin Family 6 429
Hidrosmin family 14 61
Ipriflavone family 62 2480
Rotenone family 16 107
Endothelin-1 receptor Ligand PD156707 Family 41 211
Estrogen receptor beta Ligand 2-(4-hydroxy-phenyl)benzofuran-5... 5 82
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 2,5-... 2 96
Oestrogen receptor and Estrogen receptor beta Ligand 7-chloro-... 2 27
Phospholipase A2 Inhibitor 3,9-dihydroxy-2,10-diprenylpterocap... 9 25
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 9 81
Platelet-derived growth factor receptor beta Ligand Bis(5-meth... 5 220
MO15-related protein kinase Pfmrk Inhibitor WR-289012 Family 2 17
Cannabinoid receptor 2 Ligand 2-(2-methoxybenzyl)-3h-benzo[f]c... 6 32
Aromatase Inhibitor 3,4-bis(3,4-dimethoxyphenyl)furan-2(5h)-on... 4 86
Prostaglandin G/H synthase 2 Inhibitor 3,4-dibenzyloxy-2'-hydr... 7 40
CGMP-dependent protein kinase Inhibitor Tenellone A Family 1 7
72 kDa type IV collagenase Inhibitor Lithospermic Acid Family 1 0
Creatine kinase Inhibitor 5-(4'-benzoylbiphenyl-4-yl)-2-furoic... 2 66
Liver carboxylesterase 1 Inhibitor 2-methoxy-3,4-methylenediox... 4 26
Thromboxane A2 receptor and Prostacyclin receptor ligand AGN-P... 2 30
Arachidonate 5-lipoxygenase inhibitor 7-[[3-fluoro-5-(3-hydrox... 2 10
Cytochrome P450 3A4 inhibitor 4-[(2E)-6-[(E)-3-hydroxy-2,6-dim... 3 2
Prothrombin inhibitor sodium;[3-ethoxycarbonyl-2-[[3-ethoxycar... 1 6
Arachidonate 5-lipoxygenase inhibitor 5-(1,3-benzodioxol-5-yl)... 2 2
Prelamin-A/C and Inositol monophosphatase 1 inhibitor MLS00053... 1 1
Benzopyrans Metabolite Erosnin Family 1 0
Putative NP ZINC02398203 Family 1 0
NP (z)-2-(2,3-dimethoxybenzylidene)-3-oxo-2,3-dihydrobenzofura... 9 0
NP 2-((3-(3,4-dihydro-2h-benzo[b][1,4]dioxepin-7-yl)-6-ethyl-4... 10 0
NP (z)-6-((4-bromobenzyl)oxy)-2-(3,4-dimethoxybenzylidene)benz... 13 2
(E)-3-(3,4-dimethoxyphenyl)-1-(furan-2-yl)prop-2-en-1-one NP (... 1 0
NP 4-(7-methoxybenzofuran-2-yl)-2-oxo-7-phenyl-2h-chromen-6-yl... 9 0
benzenesulfonate NP (z)-3-oxo-2-(3,4,5-trimethoxybenzylidene)-... 26 0
bromobenzoate NP ZINC09346025 Family 20 0
Putative NP ZINC09051797 Family 10 0
Putative NP ZINC09306352 Family 7 0
Putative NP ZINC09575270 Family 7 0
benzenesulfonate NP ZINC09708075 Family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00300457 DNC014143 Investigative Drug NEOLIGNAN 9-NOR-7,8-DEHYDRO-ISOLICARIN B

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48716 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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