CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3958
Family Name Sodium-dependent dopamine transporter and Sodium-dependent serotonin transporter Inhibitor 3-(4-chlorophenyl)-2-nortropene Family
No. of Seeds 5 No. of Other Members 1
Family Centroid CFAMM00300463 Functional Category Investigative Drug
Superfamily Sodium-dependent dopamine transporter and Sodium-dependent serotonin transporter Inhibitor 3-(4-chlorophenyl)-2-nortropene Superfamily
Class Class 48

Cousin Family NamesSeedsMembers
Serotonin re-uptake inhibitor tetralin derivative Sertraline f... 12 118
Alpha-1B adrenergic receptor ligand phenethylamine derivative ... 12 283
Voltage-dependent T-type calcium channel subunit alpha-1H liga... 10 397
Noradrenergic re-uptake and Serotonin re-uptake Inhibitor Sibu... 7 127
Noradrenergic re-uptake Inhibitor Phentermine Family 2 11
Nuclear receptor subfamily 1 group I member 3 ligand piperazin... 3 82
Serotonin re-uptake Inhibitor Dexfenfluramine Family 6 31
Glutamate receptor AMPA subtype and Noradrenaline uptake Ligan... 9 17
Dopamine reuptake and Noradrenergic re-uptake Inhibitor Dov 21... 16 89
Dopamine reuptake and Noradrenergic re-uptake Inhibitor GSK372... 7 61
5-hydroxytryptamine receptor 2C Ligand Lorcaserin Family 8 38
Zicronapine family 43 62
Scytalone dehydratase Inhibitor Carpropamid Family 5 2
Beta-secretase 1 Inhibitor 4-(4-fluorobenzyl)piperidine Family 2 4
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 5-(4-chloro-... 3 7
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 6 7
Dipeptidyl peptidase 4 Inhibitor 2-(2-chlorophenyl)-2-morpholi... 2 34
Dipeptidyl peptidase 4 Inhibitor N4-(4-chlorobenzyl)-2,4-diami... 10 22
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 6 24
Dipeptidyl peptidase 4 Inhibitor 1-benzyl-4-(2,4-dichloropheny... 2 10
Sodium-dependent dopamine transporter and Sodium-dependent nor... 28 71
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 17 9
Aminopeptidase N Inhibitor N1-(4-chlorobenzyl)-2-benzyl-n3-hyd... 9 86
Sodium-dependent dopamine transporter and Sodium-dependent ser... 8 2
Sodium-dependent noradrenaline transporter and Sodium-dependen... 4 2
Sigma non-opioid intracellular receptor 1 ligand NCI60_038428 ... 5 9
Sigma non-opioid intracellular receptor 1 and D(2) dopamine re... 18 4
Sigma non-opioid intracellular receptor 1 ligand 1-[2-(3,4-dic... 8 4
Sodium-dependent serotonin transporter and Sodium-dependent do... 5 6
Sodium-dependent dopamine transporter and Sodium-dependent nor... 2 0
Transporter and Sodium-dependent dopamine transporter inhibito... 3 0
Sodium-dependent dopamine transporter inhibitor [3-(4-chloroph... 1 1
Transporter and Sodium-dependent serotonin transporter inhibit... 4 8
Transporter and Sodium-dependent dopamine transporter inhibito... 6 1
Sodium-dependent dopamine transporter inhibitor N-[[(1S,3S,4R,... 1 0
Sodium-dependent serotonin transporter and Sodium-dependent no... 3 4
Sodium-dependent serotonin transporter and Sodium-dependent no... 3 3
Sodium-dependent noradrenaline transporter and Sodium-dependen... 2 12
Sodium-dependent dopamine transporter and Sodium-dependent nor... 3 1
Sodium-dependent serotonin transporter and Sodium-dependent no... 2 0
D(1A) dopamine receptor and D(2) dopamine receptor ligand A314... 3 1
Sigma non-opioid intracellular receptor 1 ligand NCI60_039912 ... 2 0
D(2) dopamine receptor and D(1A) dopamine receptor ligand AGN-... 2 1
Sodium-dependent dopamine transporter and Muscarinic acetylcho... 2 6
Sodium-dependent dopamine transporter and Sodium-dependent nor... 1 0
Sodium-dependent dopamine transporter and Sodium-dependent nor... 2 0
Kinesin-like protein KIF11 inhibitor 4-(4-chlorophenyl)-4,4-di... 1 2
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 1 10
Prelamin-A/C inhibitor CHEMBL1353052 family 1 1
Muscarinic acetylcholine receptor M2 and Muscarinic receptor 3... 1 0
Sodium-dependent noradrenaline transporter and Sodium-dependen... 1 0
1-[(E)-3-phenylprop-2-enyl]-4-[[(4S)-4-prop-1-en-2-ylcyclohexe... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00300462 CHEMBL135897 Bioactive 3-(4-chlorophenyl)-7-azabicyclo[2.2.1]heptane
CFAMM00300463 DNC014148 Investigative Drug 3-(4-Chlorophenyl)-2-nortropene

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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