CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3971
Family Name Fatty-acid amide hydrolase 1 Inhibitor 4-nitrophenyl 4-benzylpiperazine-1-carboxylate Family
No. of Seeds 5 No. of Other Members 35
Family Centroid CFAMM00300688 Functional Category Investigative Drug
Superfamily Fatty-acid amide hydrolase 1 Inhibitor 4-nitrophenyl 4-benzylpiperazine-1-carboxylate Superfamily
Class Class 2949

Cousin Family NamesSeedsMembers
Alpha adrenergic receptor Ligand Phenoxybenzamine Family 4 63
Substance-P receptor Ligand Ezlopitant Family 10 207
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Potassium voltage-gated channel subfamily H member 2 and Sodiu... 33 83
Histamine H3 receptor Ligand UCL1972 Family 3 23
Leukotriene A-4 hydrolase Inhibitor N5-[4-(phenylmethoxy)pheny... 7 49
Leukotriene A-4 hydrolase Inhibitor N-benzyl-4-[(2r)-pyrrolidi... 6 40
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 6 131
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 9 79
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-(3-morpholinop... 24 102
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 8 41
Leukotriene A-4 hydrolase Inhibitor 1-[4-(4-iodophenoxy)phenyl... 5 18
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Aromatase Inhibitor 2,3-dimethoxy-4'-amino-trans-stilbene Family 5 12
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 9 28
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 2 5
Sodium-dependent serotonin transporter inhibitor SureCN3890472... 2 0
Potassium voltage-gated channel subfamily H member 2 and Melan... 9 4
Substance-P receptor ligand 1-[(5-amino-2-methoxyphenyl)methyl... 3 5
Carbonic anhydrase 14 and Carbonic anhydrase 9 inhibitor 6-met... 2 6
Sodium-dependent serotonin transporter and Acetylcholinesteras... 1 0
Histamine H3 receptor and Sodium-dependent serotonin transport... 2 1
Coagulation factor X and Cationic trypsin inhibitor 3-[(E)-3-[... 3 2
Histamine H3 receptor and Sodium-dependent serotonin transport... 1 2
Substance-P receptor ligand CP 141938 family 1 0
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 1 2
Monoglyceride lipase and Fatty-acid amide hydrolase 1 inhibito... 1 1
Monoglyceride lipase and Fatty-acid amide hydrolase 1 inhibito... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00300683 CHEMBL46596 Bioactive 1-[(4-fluorophenyl)methyl]-4-[(4-nitrophenoxy)methyl]piperidine
CFAMM00300694 CHEMBL601002 Bioactive AGN-PC-07AJW0
CFAMM00300708 CHEMBL540578 Bioactive AGN-PC-07C28I
CFAMM00300706 CHEMBL2146861 Bioactive 1-[2-(4-methoxyphenyl)ethyl]-4-[2-(4-nitrophenyl)ethyl]piperazine
CFAMM00300688 DNC014183 Investigative Drug 4-Nitrophenyl 4-Benzylpiperazine-1-carboxylate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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