CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3977
Family Name Amine oxidase [flavin-containing] A Inhibitor 6-chloro-n-(2-morpholinoethyl)nicotinamide Family
No. of Seeds 5 No. of Other Members 3
Family Centroid CFAMM00300736 Functional Category Investigative Drug
Superfamily SUR2-type K(ATP) channel Ligand Nicorandil Superfamily
Class Class 11

Cousin Family NamesSeedsMembers
Cytochrome P450 11B1, mitochondrial Inhibitor Metyrapone Family 9 243
SUR2-type K(ATP) channel Ligand Nicorandil Family 5 85
Mitogen-activated protein kinase 14 Inhibitor Losmapimod Family 5 154
Poly [ADP-ribose] polymerase 1 Inhibitor 2-(4-chlorophenyl)-5-... 2 8
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 93
Amine oxidase [flavin-containing] B Inhibitor Lazebemide Family 2 13
M-phase inducer phosphatase 3 Inhibitor NSC-663284 Family 1 12
Cannabinoid receptor 1 Ligand N-phenyl-5,6-dip-tolylpyrazine-2... 11 26
C-C chemokine receptor type 5 Ligand GT-1282 Family 21 14
Bifunctional epoxide hydrolase 2 Inhibitor N-(3,3-diphenyl-pro... 6 14
Bifunctional epoxide hydrolase 2 Inhibitor 6-amino-n-(2,4-dich... 10 116
Sodium channel protein type 10 subunit alpha Ligand N-benzyl-5... 11 46
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 1 4
Translocator protein inhibitor (2E)-N-(4-chlorophenyl)-N-methy... 2 13
Prelamin-A/C and Tyrosyl-DNA phosphodiesterase 1 inhibitor nif... 1 0
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[(E... 2 1
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 5 4
D(3) dopamine receptor and Alpha-1D adrenergic receptor ligand... 1 0
Dual specificity protein kinase CLK4 and Mitogen-activated pro... 1 1
Seprase and Prolyl endopeptidase inhibitor [(2R)-1-[(2R)-2-[(2... 4 2
Neutrophil elastase inhibitor N-[(2S)-3-methyl-1-oxo-1-[(2S)-2... 4 4
C-X-C chemokine receptor type 2 ligand 6-chloro-N-(4-fluorophe... 1 0


External ID

Functional Category

Molecule Name

CFAMM00300735 DNC014216 Investigative Drug 5,6-Dichloro-N-(3-morpholinopropyl)nicotinamide
CFAMM00300744 DNC014206 Investigative Drug 2-Chloro-N-(2-morpholinoethyl)nicotinamide
CFAMM00300743 DNC014208 Investigative Drug 4-Chloro-N-(2-morpholinoethyl)nicotinamide
CFAMM00300737 DNC014212 Investigative Drug 5,6-Dichloro-N-(2-morpholinoethyl)nicotinamide
CFAMM00300736 DNC014210 Investigative Drug 6-Chloro-N-(2-morpholinoethyl)nicotinamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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