CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3985
Family Name 72 kDa type IV collagenase Inhibitor Lithospermic Acid Family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00300802 Functional Category Investigative Drug
Superfamily Protein kinase C beta type and Protein kinase C alpha type Binder Superfamily
Class Class 776

Cousin Family NamesSeedsMembers
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor Mycophenola... 4 353
Heat shock protein 90, putative Inhibitor Cromoglicate Family 14 2827
DNA Binder Methoxsalen Family 10 1638
D-alanyl-D-alanine carboxypeptidase Inhibitor B-lactams Family 59 1364
Aldehyde oxidase Inhibitor Isovanillin Family 6 429
Hidrosmin family 14 61
Ipriflavone family 62 2480
Rotenone family 16 107
taste receptor Ligand Cynarin Family 6 124
Chromomycin A3 family 7 14
Leukotriene B4 receptor 1 Ligand LY293111 Family 24 79
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 9 123
Multidrug resistance protein Inhibitor Curcumin I Family 19 278
Interleukin-1 beta Inhibitor Diacerein Family 3 77
Glucose-6-phosphate translocase Inhibitor Kodaistatin A Family 1 0
Endothelin-1 receptor Ligand PD156707 Family 41 211
Peroxisome proliferator-activated receptor gamma Ligand (2s)-2... 10 126
Arachidonate 15-lipoxygenase Inhibitor Isoscopoletin Family 5 98
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 2,5-... 2 96
Endothelin B receptor and Endothelin-1 receptor Ligand PD-1631... 9 13
Protein kinase C alpha type and Protein kinase C beta type Inh... 7 1
Phospholipase A2 Inhibitor 3,9-dihydroxy-2,10-diprenylpterocap... 9 25
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 9 81
Oestrogen receptor and Estrogen receptor beta Ligand 3,8-dihyd... 20 57
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor Ellagi... 1 11
Tyrosine-protein phosphatase non-receptor type 1 Ligand Phelli... 1 1
Protein kinase C alpha type and Protein kinase C beta type Inh... 2 1
MO15-related protein kinase Pfmrk Inhibitor WR-289012 Family 2 17
Squalene monooxygenase Inhibitor Octyl_gallate Family 5 5
Cytochrome P450 3A4 Inhibitor (-)-cubebininolide Family 4 28
Aromatase Inhibitor 3,4-bis(3,4-dimethoxyphenyl)furan-2(5h)-on... 4 86
Cytochrome P450 3A4 Inhibitor Diethoxyflourescein Family 3 9
Voltage-dependent N-type calcium channel subunit alpha-1B Liga... 1 6
Heat shock cognate 71 kDa protein Inhibitor NSC-119913 Family 2 1
Epidermal growth factor receptor Ligand 3-(3-chloro-phenyl)-5,... 10 64
Protein farnesyltransferase subunit beta Inhibitor Cylindrol A... 3 43
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 3 0
Prostaglandin G/H synthase 2 Inhibitor 3,4-dibenzyloxy-2'-hydr... 7 40
Androgen receptor Ligand Palodesangren E Family 12 43
CGMP-dependent protein kinase Inhibitor Tenellone A Family 1 7
Prostaglandin G/H synthase 2 Inhibitor Neolignan 9-nor-7,8-deh... 1 7
Liver carboxylesterase 1 Inhibitor 2-methoxy-3,4-methylenediox... 4 26
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 6 6
Endothelin-1 receptor ligand (2S)-2-(1,3-benzodioxol-5-yl)-4-m... 17 0
Thromboxane A2 receptor and Prostacyclin receptor ligand AGN-P... 2 30
Endothelin-1 receptor ligand SureCN8117947 family 1 3
Amine oxidase [flavin-containing] B and Amine oxidase [flavin-... 7 13
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 7
Endothelin-1 receptor and Endothelin B receptor ligand SureCN7... 2 2
Survival motor neuron protein and Prelamin-A/C inhibitor CHEMB... 2 32
Sugar Acids and Derivatives Metabolite 3-Methoxy-4-hydroxyphen... 1 6
Benzopyrans Metabolite (-)-trans-3,4-Dihydro-4,8-dihydroxy-3-m... 1 0
Prenol Lipids Metabolite Rosmadial Family 1 0
NP 2-((3-(3,4-dihydro-2h-benzo[b][1,4]dioxepin-7-yl)-6-ethyl-4... 10 0
NP 4-(7-methoxybenzofuran-2-yl)-2-oxo-7-phenyl-2h-chromen-6-yl... 9 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00300802 DNC014243 Investigative Drug lithospermic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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