CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3986
Family Name Sodium-dependent serotonin transporter Inhibitor 2-n-ethylamino-1-(4-methylthiophenyl)propane Family
No. of Seeds 14 No. of Other Members 5
Family Centroid CFAMM00300820 Functional Category Investigative Drug
Superfamily Amine oxidase [flavin-containing] A and Amine oxidase [flavin-containing] B Binder Superfamily
Class Class 2406

Cousin Family NamesSeedsMembers
Alpha-1B adrenergic receptor ligand phenethylamine derivative ... 12 283
Histamine H1 receptor ligand piperazine derivative Cyclizine F... 16 140
Muscarinic acetylcholine receptor M5 Ligand Metixene Family 5 24
Amine oxidase [flavin-containing] B Inhibitor Selegiline Family 6 26
Noradrenergic re-uptake Inhibitor Phentermine Family 2 11
Serotonin re-uptake Inhibitor Dexfenfluramine Family 6 31
Glutamate receptor AMPA subtype and Noradrenaline uptake Ligan... 9 17
Beta-secretase 1 Inhibitor 4-(4-fluorobenzyl)piperidine Family 2 4
Potassium voltage-gated channel subfamily H member 2 Ligand 4-... 4 26
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 15 11
Histamine H3 receptor Ligand 1-[2-(2,4,6-trimethyl-phenyl)-eth... 9 15
Sodium-dependent dopamine transporter and Sodium-dependent nor... 28 71
D(2) dopamine receptor Ligand 4-[3-(methylsulfonyl)phenyl]-1-p... 2 2
5-hydroxytryptamine receptor 1A Ligand 2-(biphenyl-3-ylthio)-n... 1 3
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 2 4
Sodium-dependent serotonin transporter and Sodium-dependent no... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00300816 DNC014263 Investigative Drug 2-N-Ethylamino-1-(4-methylthiophenyl)butane
CFAMM00300822 DNC014262 Investigative Drug 2-N-Methylamino-1-(4-methylthiophenyl)butane
CFAMM00300821 DNC014245 Investigative Drug 2-N-Methylamino-1-(4-methylthiophenyl)propane
CFAMM00300820 DNC014246 Investigative Drug 2-N-Ethylamino-1-(4-methylthiophenyl)propane
CFAMM00300826 DNC014266 Investigative Drug 2-N-Cyclopropylamino-1-(4-methylthiophenyl)butane
CFAMM00300819 DNC014247 Investigative Drug 2-N-Allylamino-1-(4-methylthiophenyl)propan
CFAMM00300810 DNC014259 Investigative Drug 2-N-Ethylamino-1-(4-ethylthiophenyl)butane
CFAMM00300825 DNC014267 Investigative Drug 2-N-Propargylamino-1-(4-methylthiophenyl)butane
CFAMM00300818 DNC014248 Investigative Drug 2-N-Propargylamino-1-(4-methylthiophenyl)propane
CFAMM00300809 DNC014256 Investigative Drug 2-N-Ethylamino-1-(4-ethylthiophenyl)propane
CFAMM00300824 DNC014264 Investigative Drug 2-N-(n-Propyl)amino-1-(4-methylthiophenyl)butane
CFAMM00300817 DNC014249 Investigative Drug 2-N,N-Dimethylamino-1-(4-methylthiophenyl)propane
CFAMM00300808 DNC014255 Investigative Drug 2-N-Methylamino-1-(4-ethylthiophenyl)propane
CFAMM00300823 DNC014265 Investigative Drug 2-N-(Isopropyl)amino-1-(4-methylthiophenyl)butane

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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