CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID4002
Family Name Acetylcholinesterase and Cholinesterase Inhibitor 1,4-di(berberine-9-o-yl)ethane Dibromide Family
No. of Seeds 5 No. of Other Members 0
Family Centroid CFAMM00301185 Functional Category Investigative Drug
Superfamily Na+-K+-ATPase transmembrane protein Inhibitor Sanguinarine Superfamily
Class Class 24

Cousin Family NamesSeedsMembers
Beta adrenergic receptor ligand monosubstituted indole derivat... 14 475
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 53 741
Na+-K+-ATPase transmembrane protein Inhibitor Sanguinarine Family 8 20
Hemoglobin subunit alpha Inhibitor 2-[(2-methoxy-5-methylpheno... 5 48
Platelet-derived growth factor receptor alpha and Platelet-der... 2 9
Platelet-derived growth factor receptor beta and Epidermal gro... 3 7
5-hydroxytryptamine receptor 1A ligand (2S)-1-[(3S,4R)-3-(1,3-... 2 0
Cannabinoid receptor 1 ligand AGN-PC-088XYA family 4 6
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN6... 7 4
Hepatocyte growth factor receptor ligand 1-[(E)-(2,4-difluorop... 2 0
Histamine H3 receptor and Sodium-dependent serotonin transport... 3 2
Lanosterol synthase inhibitor AGN-PC-07BZTX family 2 0
Acetylcholinesterase and Butyrylcholinesterase inhibitor AGN-P... 2 10
Sodium/glucose cotransporter 2 and Sodium/glucose cotransporte... 2 2


External ID

Functional Category

Molecule Name

CFAMM00301189 DNC014367 Investigative Drug 9-O-[3-(4-Nitro-phenoxyl)butyl]-berberine bromide
CFAMM00301188 DNC014366 Investigative Drug 9-O-[3-(4-Bromo-phenoxyl)butyl]-berberine bromide
CFAMM00301187 DNC014370 Investigative Drug 1,2-Di(berberine-9-O-yl)ethane dibromide
CFAMM00301186 DNC014371 Investigative Drug 1,3-Di(berberine-9-O-yl)ethane dibromide
CFAMM00301185 DNC014372 Investigative Drug 1,4-Di(berberine-9-O-yl)ethane dibromide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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