CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID4033
Family Name Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-(3-chlorobenzyl)methylphenidate Family
No. of Seeds 8 No. of Other Members 30
Family Centroid CFAMM00301378 Functional Category Investigative Drug with Natural Product
Superfamily Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-(3-chlorobenzyl)methylphenidate Superfamily
Class Class 187

Cousin Family NamesSeedsMembers
Sodium-dependent dopamine transporter inhibitor substituted ph... 22 416
Alpha-2 adrenergic receptor ligand opiate Meperidine Family 13 76
Muscarinic acetylcholine receptor M5 ligand Tropane alkaloid A... 18 12
Mu-type opioid receptor Ligand Anileridine Family 3 18
Mu-type opioid receptor Ligand Diphenoxylate Family 5 6
Sodium-dependent dopamine transporter Inhibitor Ioflupane I-12... 130 181
Dopamine reuptake and Noradrenergic re-uptake Inhibitor GSK372... 7 61
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-ri... 5 12
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 5 6
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-3'... 14 11
Sodium-dependent dopamine transporter and Sodium-dependent ser... 8 8
Sodium-dependent serotonin transporter and Sodium-dependent do... 5 0
Sodium-dependent dopamine transporter and Sodium-dependent ser... 3 18
Sodium-dependent serotonin transporter and Transporter inhibit... 6 9
Sodium-dependent dopamine transporter inhibitor methyl (2R)-2-... 1 0
Transporter and Sodium-dependent serotonin transporter inhibit... 8 6
Sodium-dependent dopamine transporter inhibitor ethyl (3S,4S)-... 6 11
Sodium-dependent serotonin transporter inhibitor CHEMBL265808 ... 1 0
Sodium-dependent serotonin transporter and Transporter inhibit... 4 2
Transporter and Sodium-dependent serotonin transporter inhibit... 4 0
Nociceptin receptor and Mu-type opioid receptor ligand (1R,5R)... 4 9
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 1 0
Free fatty acid receptor 1 ligand (3R,4R)-3-(3,4-dichloropheny... 1 0
Sodium-dependent serotonin transporter and Transporter inhibit... 1 0
Sodium-dependent serotonin transporter and Transporter inhibit... 1 0
Transporter and Sodium-dependent dopamine transporter inhibito... 1 5
Transporter and Sodium-dependent dopamine transporter inhibito... 2 1
Sodium-dependent dopamine transporter and Transporter inhibito... 1 1
Sodium- and chloride-dependent GABA transporter 1 inhibitor Su... 8 8
Sodium-dependent serotonin transporter and Sodium-dependent do... 1 0
[(1R,9aR)-1,2,3,4,5,6,7,8,9,9a-decahydroquinolizin-5-ium-1-yl]... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00301405 CHEMBL553765 Bioactive methyl (2S)-2-(3-chlorophenyl)-2-[(2S)-piperidin-2-yl]acetate;hydrochloride
CFAMM00301377 CHEMBL19607 Bioactive methyl (2R)-2-(3-chlorophenyl)-2-piperidin-2-ylacetate
CFAMM00301409 CHEMBL1944826 Bioactive ethyl (1S,3S,4S,5R)-3-(4-chlorophenyl)-8-[(4-fluorophenyl)methyl]-8-azabicyclo[3.2.1]octane-4-carboxylate
CFAMM00301395 CHEMBL1253271 Bioactive methyl (2R)-2-(3-chlorophenyl)-2-[(2R)-piperidin-2-yl]acetate
CFAMM00301385 DNC014460 Investigative Drug (+/-)-threo-N-(4-Chlorobenzyl)methylphenidate
CFAMM00301378 DNC014453 Investigative Drug (+/-)-threo-N-(3-Chlorobenzyl)methylphenidate
CFAMM00301394 DNC014480 Investigative Drug (+/-)-threo-N-Benzyl-3'-chloromethylphenidate
CFAMM00301379 DNC014458 Investigative Drug (+/-)-threo-N-(2-Chlorobenzyl)methylphenidate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27698 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543