CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID4034
Family Name Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-(4-nitrobenzyl)methylphenidate Family
No. of Seeds 11 No. of Other Members 20
Family Centroid CFAMM00301438 Functional Category Investigative Drug
Superfamily Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-(4-nitrobenzyl)methylphenidate Superfamily
Class Class 2972

Cousin Family NamesSeedsMembers
Sodium-dependent dopamine transporter inhibitor substituted ph... 22 416
Muscarinic acetylcholine receptor Ligand Mepenzolate Family 35 11
Mu-type opioid receptor Ligand Anileridine Family 3 18
Sodium-dependent dopamine transporter Inhibitor Ioflupane I-12... 130 181
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 19 32
Alpha-1A adrenergic receptor Ligand SNAP-6201 Family 41 94
Sodium-dependent dopamine transporter and Sodium-dependent ser... 8 8
D(4) dopamine receptor and D(2) dopamine receptor ligand methy... 2 11
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 5 7
Sodium-dependent serotonin transporter and Sodium-dependent do... 2 1
Sodium-dependent dopamine transporter and Sodium-dependent nor... 2 5
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 4 0
Sodium-dependent dopamine transporter inhibitor methyl (2R)-2-... 1 0
Sodium-dependent dopamine transporter inhibitor 2-(4-aminophen... 5 0
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 1 4
Sodium-dependent dopamine transporter inhibitor methyl (1R,3S)... 1 0
Sodium-dependent dopamine transporter inhibitor 2-[4-[(2-bromo... 1 0
Sodium-dependent dopamine transporter inhibitor methyl (1R,3S)... 1 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00301417 CHEMBL555580 Bioactive AGN-PC-07BZ2I
CFAMM00301430 CHEMBL1237136 Bioactive methyl (1R)-8-methyl-3-(4-nitrophenyl)-8-azabicyclo[3.2.1]octane-4-carboxylate
CFAMM00301423 CHEMBL542131 Bioactive AGN-PC-07BZ0B
CFAMM00301442 CHEMBL375499 Bioactive methyl 2-[(4-benzylpiperidin-1-yl)methyl]-1-(4-nitrophenyl)cyclopropane-1-carboxylate
CFAMM00301434 CHEMBL60609 Bioactive AGN-PC-002GDN
CFAMM00301433 CHEMBL301174 Bioactive AGN-PC-073RNC
CFAMM00301439 CHEMBL300511 Bioactive AGN-PC-073RND
CFAMM00301419 CHEMBL214230 Bioactive methyl (3S,4S)-8-methyl-3-[4-(4-nitrophenyl)phenyl]-8-azabicyclo[3.2.1]octane-4-carboxylate
CFAMM00301432 CHEMBL222235 Bioactive methyl 2-[(4-hydroxy-4-phenylpiperidin-1-yl)methyl]-1-(4-nitrophenyl)cyclopropane-1-carboxylate
CFAMM00301438 DNC014461 Investigative Drug (+/-)-threo-N-(4-Nitrobenzyl)methylphenidate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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