CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID4039
Family Name Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-benzyl-3',4'-dichlororitalinol Family
No. of Seeds 5 No. of Other Members 6
Family Centroid CFAMM00301682 Functional Category Investigative Drug with Natural Product
Superfamily Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-benzyl-3',4'-dichlororitalinol Superfamily
Class Class 1325

Cousin Family NamesSeedsMembers
Sodium-dependent dopamine transporter inhibitor substituted ph... 22 416
Serotonin re-uptake inhibitor tetralin derivative Sertraline f... 12 118
Nuclear receptor subfamily 1 group I member 3 ligand piperazin... 3 82
Histamine H1 receptor Ligand Chlophedianol Family 4 46
Dopamine reuptake and Noradrenergic re-uptake Inhibitor GSK372... 7 61
Zicronapine family 43 62
Peptide deformylase, mitochondrial Inhibitor Hydroxamates Family 6 17
Glutamate receptor ionotropic, NMDA 2B and Glutamate receptor ... 9 7
Sodium-dependent serotonin transporter Inhibitor Tefludazine F... 8 9
Beta-1 adrenergic receptor and Beta-2 adrenergic receptor Liga... 1 8
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 8 30
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-3'... 14 11
Sigma non-opioid intracellular receptor 1 ligand 1-[2-(3,4-dic... 8 4
Transporter and Sodium-dependent dopamine transporter inhibito... 3 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 6 0
D(1A) dopamine receptor and D(3) dopamine receptor ligand 2-[4... 1 0
Sodium-dependent dopamine transporter inhibitor ethyl (3S,4S)-... 6 11
Sodium-dependent dopamine transporter inhibitor (1R)-1-[(3S,4S... 1 1
Nociceptin receptor and Mu-type opioid receptor ligand 8-[(2-c... 2 2
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 1 0
Free fatty acid receptor 1 ligand (3R,4R)-3-(3,4-dichloropheny... 1 0
Sodium-dependent serotonin transporter and Sodium-dependent no... 2 0
Transporter and Sodium-dependent dopamine transporter inhibito... 1 5
D(1A) dopamine receptor and D(3) dopamine receptor ligand (2S,... 5 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00301674 CHEMBL1254758 Bioactive (2R)-1-benzyl-2-[(1R)-1-(3,4-dichlorophenyl)-2-methoxyethyl]piperidine
CFAMM00301682 DNC014483 Investigative Drug (+/-)-threo-N-Benzyl-3',4'-dichlororitalinol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27744 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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