CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID4044
Family Name Arachidonate 5-lipoxygenase Inhibitor 5-methyl-n-phenylbenzo[d]oxazol-2-amine Family
No. of Seeds 5 No. of Other Members 13
Family Centroid CFAMM00301745 Functional Category Investigative Drug with Natural Product
Superfamily Arachidonate 5-lipoxygenase Binder Superfamily 2
Class Class 2136

Cousin Family NamesSeedsMembers
Substance-P receptor Ligand R 673 Family 2 127
Peroxisome proliferator-activated receptor gamma and Peroxisom... 15 94
Melatonin receptor type 1B Ligand N-(3-benzooxazol-7-yl-propyl... 26 101
Peroxisome proliferator-activated receptor gamma Ligand SB-213... 2 54
Fatty-acid amide hydrolase 1 Inhibitor (z)-1-(benzo[d]oxazol-2... 2 27
Vascular endothelial growth factor receptor 1 and Vascular end... 6 28
Vascular endothelial growth factor receptor 1 and Vascular end... 4 44
Arachidonate 5-lipoxygenase Inhibitor 5-chloro-n-phenylbenzo[d... 3 15
Neutrophil elastase Inhibitor Cbz-val-pro-val-(2-benzoxazole) ... 32 64
Leukotriene A-4 hydrolase Inhibitor 2-[4-(2-azepan-1-ylethoxy)... 5 15
5-hydroxytryptamine receptor 3A and Neuronal acetylcholine rec... 2 26
Fatty-acid amide hydrolase 1 Inhibitor 3-(benzo[d]oxazol-2-yl)... 1 6
Arachidonate 5-lipoxygenase Inhibitor 5-methoxy-n-phenylbenzo[... 2 4
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 1 0
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK1 ... 5 25
Somatostatin receptor type 5 and Potassium voltage-gated chann... 2 21
Transient receptor potential cation channel subfamily V member... 7 5
Prelamin-A/C inhibitor CHEMBL1374443 family 1 6
Prostaglandin D2 receptor ligand 2-methoxy-N-[2-(4-methoxyphen... 2 2
Cannabinoid receptor 2 ligand [4-(5-tert-butyl-1,3-benzoxazol-... 4 1
Orexin receptor type 1 and Orexin receptor type 2 ligand [(2S,... 2 3
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 14 24
Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-[4-(1,3-benzoxazol... 3 4
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 8
Prostaglandin E synthase inhibitor 1-[5-chloro-6-(4-fluorophen... 8 27
Integrin beta-1 and Integrin alpha-4 inhibitor 4-[[(2S,5S)-5-(... 20 10
Gamma-aminobutyric acid receptor subunit pi and Gamma-aminobut... 5 2
Cathepsin S and Cathepsin L1 inhibitor (2S)-2-(1,3-benzoxazol-... 1 9
Cathepsin S and Cathepsin L1 inhibitor SureCN5361439 family 2 4
C-C chemokine receptor type 3 ligand SureCN6338683 family 1 2
Vascular endothelial growth factor receptor 2 and Vascular end... 10 6
Somatostatin receptor type 5 ligand SureCN3572493 family 1 3
Inosine-5'-monophosphate dehydrogenase 2 inhibitor AGN-PC-074D... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00301744 DNC014513 Investigative Drug N-(4-Ethylphenyl)-5-methylbenzo[d]oxazol-2-amine
CFAMM00301765 DNC014508 Investigative Drug N-Phenylbenzo[d]oxazol-2-amine
CFAMM00301747 DNC014514 Investigative Drug N-(2-Ethylphenyl)-5-methylbenzo[d]oxazol-2-amine
CFAMM00301745 DNC014512 Investigative Drug 5-Methyl-N-phenylbenzo[d]oxazol-2-amine
CFAMM00301766 DNC014509 Investigative Drug N-(4-Ethylphenyl)benzo[d]oxazol-2-amine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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