CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID4083
Family Name NADH-ubiquinone oxidoreductase chain 3 Inhibitor 6-thiophen-3-yl-imidazo[2,1-b]thiazole Family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00302150 Functional Category Investigative Drug
Superfamily 5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine receptor 2B Binder Superfamily
Class Class 392

Cousin Family NamesSeedsMembers
Fumarate reductase flavoprotein subunit Inhibitor Thiabendazol... 3 20
Vascular endothelial growth factor Inhibitor PTC299 Family 6 145
Steroid 17-alpha-hydroxylase/17,20 lyase Inhibitor 1-(1-(4-thi... 3 36
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 4 22
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-chlo... 11 20
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 6 55
Potassium voltage-gated channel subfamily H member 2 and Neuro... 2 3
5-hydroxytryptamine receptor 6 ligand 6-chloro-5-[1-(1-methylp... 9 0
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 3 10
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 7 21
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 1
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 2 1
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 1 0
Alpha-1A adrenergic receptor and Alpha-2A adrenergic receptor ... 1 0
Tyrosine-protein kinase SYK and Tyrosine-protein kinase ZAP-70... 4 1
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 2 4
D(4) dopamine receptor and D(2) dopamine receptor ligand 3-(1-... 1 0
Prostaglandin G/H synthase 2 inhibitor AGN-PC-00FW8Y family 1 1
Cytochrome P450 11B1, mitochondrial and Cytochrome P450 11B2, ... 1 1
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 3 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00302150 DNC014631 Investigative Drug 6-Thiophen-3-yl-imidazo[2,1-b]thiazole
CFAMM00302149 DNC014633 Investigative Drug 6-Thiophen-2-yl-imidazo[2,1-b]thiazole

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26190 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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