CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID4088
Family Name DNA topoisomerase Inhibitor 6-(3-iodo-phenylamino)-1h-pyrimidine-2,4-dione Family
No. of Seeds 2 No. of Other Members 5
Family Centroid CFAMM00302192 Functional Category Investigative Drug
Superfamily DNA topoisomerase Binder Superfamily
Class Class 2986

Cousin Family NamesSeedsMembers
Sodium channel Ligand iminostilbene derivative (tricyclic stru... 2 46
Peptide deformylase, mitochondrial Inhibitor Proguanil Family 8 46
Metabotropic glutamate receptor 5 Ligand Mcn3377 Family 1 12
Bifunctional epoxide hydrolase 2 Inhibitor 1-cyclohexyl-3-phen... 5 65
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-chloro-phenyl)... 5 50
Carbonic anhydrase 2 and Carbonic anhydrase 4 Inhibitor 1-(3,4... 2 9
Cannabinoid receptor 1 Ligand 1-(bis(4-chlorophenyl)methyl)-3-... 4 44
Kinesin-like protein KIF11 Inhibitor N-[4'-(trifluoromethyl)-4... 7 134
5-hydroxytryptamine receptor 3A Ligand 1-(biphenyl-4-yl)-3-(4-... 20 67
Bifunctional epoxide hydrolase 2 Inhibitor 1-phenyl-3-(1-propi... 22 183
Tyrosinase Inhibitor 1-hydroxy-3-phenylurea Family 2 10
DNA topoisomerase Inhibitor 6-p-tolylamino-1h-pyrimidine-2,4-d... 3 17
DNA topoisomerase Inhibitor 6-(indan-5-ylamino)-1h-pyrimidine-... 2 0
DNA topoisomerase Inhibitor 6-(naphthalen-2-ylamino)-1h-pyrimi... 2 1
DNA polymerase Inhibitor 6-(4-bromo-phenylamino)-1h-pyrimidine... 2 1
C-C chemokine receptor type 2 and C-C chemokine receptor type ... 2 8
D(3) dopamine receptor and D(2) dopamine receptor ligand 3-[4-... 4 23
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 3
Inosine-5'-monophosphate dehydrogenase inhibitor 1-(3,4-dichlo... 1 1
Carbonic anhydrase 1 and Carbonic anhydrase 2 inhibitor 1-(4-c... 1 0
3-hydroxyacyl-CoA dehydrogenase type-2 and 15-hydroxyprostagla... 2 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00302192 DNC014642 Investigative Drug 6-(3-Iodo-phenylamino)-1H-pyrimidine-2,4-dione
CFAMM00302191 DNC014643 Investigative Drug 6-(4-Chloro-phenylamino)-1H-pyrimidine-2,4-dione

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27254 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543