CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID4093
Family Name cAMP-dependent protein kinase type I-alpha regulatory subunit and cAMP-dependent protein kinase type II-beta regulatory subunit Inhibitor Adcahxarg4nh(ch2)6nh2 Family
No. of Seeds 12 No. of Other Members 0
Family Centroid CFAMM00302214 Functional Category Investigative Drug
Superfamily Adenosine receptor A2a Binder Superfamily
Class Class 172

Cousin Family NamesSeedsMembers
Adenosine receptor A3 ligand purine nucleoside Adenosine Family 47 847
Bucladesine family 1 1
Adenosine receptor A2a Ligand Atl-146e Family 33 94
TG-C family 11 208
Histamine N-methyltransferase Inhibitor S-adenosyl-l-homocyste... 2 3
Adenosine receptor A3 and Adenosine receptor A1 ligand (2S,3S,... 16 6
Adenosine receptor A1 and Adenosine receptor A2a ligand (1S,3S... 3 0
Adenosine receptor A3 and Adenosine receptor A1 ligand (2S,3S,... 2 10
Adenosine receptor A1 and Adenosine receptor A2b ligand (2R,3R... 9 0
Adenosylhomocysteinase and Adenosine deaminase inhibitor AGN-P... 2 1
Adenosine receptor A2a and Adenosine receptor A2b ligand Cgs-2... 1 2
Adenosine receptor A1 ligand CHEMBL411245 family 1 0
Adenosine receptor A2a and Adenosine receptor A1 ligand (2S,3S... 1 0
Putative Bioactive [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-di... 2 0


External ID

Functional Category

Molecule Name

CFAMM00302221 CHEMBL279185 Bioactive (2S,3S,4R,5R)-N-[6-[[(2R)-1-[[(2R)-1-[[(2R)-1-[[(2R)-1-[[(2R)-1-[[(2R)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-6-oxohexyl]-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolane-2-carboxamide
CFAMM00302220 CHEMBL495088 Bioactive (2S,3S,4R,5R)-N-[6-[[(2R)-6-amino-1-[[8-[[(2R)-1-[[(2R)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-8-oxooctyl]amino]-1-oxohexan-2-yl]amino]-6-oxohexyl]-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolane-2-carboxamide
CFAMM00302216 CHEMBL506331 Bioactive (2S,3S,4R,5R)-N-[6-[[(2R)-6-amino-1-[[6-[[(2S)-1-[[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-6-oxohexyl]amino]-1-oxohexan-2-yl]amino]-6-oxohexyl]-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolane-2-carboxamide
CFAMM00302214 DNC014666 Investigative Drug AdcAhxArg4NH(CH2)6NH2
CFAMM00302213 DNC014667 Investigative Drug AdcAhxArg4Lys(biotin)-PEG-OMe
CFAMM00302219 DNC014680 Investigative Drug AdoC(Dpr)2AlaArg6
CFAMM00302218 DNC014806 Investigative Drug ARC-1028
CFAMM00302217 DNC014673 Investigative Drug AdoC(beta-Ala)Arg6
CFAMM00302215 DNC014674 Investigative Drug AdoC(GABA)Arg6

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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Computer-aided Drug Design
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