CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Prostaglandin E synthase Inhibitor L-655240 Family
No. of Seeds 3 No. of Other Members 46
Family Centroid CFAMM00190651 Functional Category Investigative Drug
Superfamily Setipiprant Superfamily
Class Class 1218

Cousin Family NamesSeedsMembers
Prostaglandin G/H synthase 2 Inhibitor Carprofen Family 1 5
Indoleamine 2,3-dioxygenase 1 Inhibitor L-tryptophan Family 8 328
Proteinase-activated receptor 1 Ligand SCH-530348 Family 20 215
Arachidonate 5-lipoxygenase Inhibitor Licofelone Family 2 6
Prostaglandin D2 receptor 2 Ligand AZD1981 Family 11 28
3-hydroxy-3-methylglutaryl-coenzyme A reductase Inhibitor MK-0... 3 32
Fatty acid-binding protein, adipocyte and Fatty acid-binding p... 3 11
Cannabinoid receptor 2 Ligand JWH-204 Family 6 10
Prostaglandin D2 receptor 2 Ligand L-888607 Family 2 22
Prostaglandin E2 receptor EP4 subtype and Prostaglandin D2 rec... 8 17
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 1 6
Prostaglandin D2 receptor and Thromboxane A2 receptor ligand S... 3 4
NS5B protein inhibitor AC1NQMYP family 5 0
Substance-P receptor ligand SureCN7796965 family 9 1
Prostaglandin D2 receptor and Thromboxane A2 receptor ligand A... 5 3
Prostaglandin D2 receptor and Prostaglandin E2 receptor EP2 su... 2 0
Prostaglandin D2 receptor 2 and Prostaglandin G/H synthase 1 l... 3 17
Prostaglandin D2 receptor 2 ligand SureCN317401 family 3 8
Prostaglandin D2 receptor 2 ligand 2-[3-[(3-chlorophenyl)-meth... 1 0
Prostaglandin E synthase 2 inhibitor AGN-PC-075D2E family 1 0
Cysteinyl leukotriene receptor 1 ligand 3-[5-[[3-[(E)-2-(7-chl... 4 0


External ID

Functional Category

Molecule Name

CFAMM00190656 DNC004565 Investigative Drug L-657925
CFAMM00190663 DNC000953 Investigative Drug MK-886
CFAMM00190651 DNC014756 Investigative Drug L-655240

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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