CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID4111
Family Name Calpain Inhibitor SJA-6017 Family
No. of Seeds 2 No. of Other Members 12
Family Centroid CFAMM00302638 Functional Category Investigative Drug
Superfamily Calpain Inhibitor SJA-6017 Superfamily
Class Class 3001

Cousin Family NamesSeedsMembers
Thymidylate synthase Inhibitor N-[tosyl-d-prolinyl]amino-ethan... 1 10
Cathepsin B and Cathepsin S Inhibitor Ac-hphe-leu-ala-leuvsme ... 17 51
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-(2-p... 6 19
Calpain-1 catalytic subunit inhibitor 6-chloro-2-methyl-1,1-di... 3 9
Cathepsin L1 and Cathepsin B inhibitor (2S)-3-methyl-N-[(2S)-4... 7 24
Pol polyprotein inhibitor Lysine Sulfonamide 11c family 3 73
Disintegrin and metalloproteinase domain-containing protein 17... 6 5
Matrix metalloproteinase-9 and Stromelysin-1 inhibitor N-[(2S)... 1 0
Proteasome subunit beta type-5 inhibitor (2S)-N'-(2,2-dimethyl... 2 9
Neutrophil collagenase and Collagenase 3 inhibitor (2R)-2-[2-a... 1 0
72 kDa type IV collagenase and Stromelysin-1 inhibitor (2R)-N-... 7 1
Neutrophil elastase inhibitor 1-[(2S)-3-methyl-2-(naphthalen-2... 3 1
Neutrophil elastase inhibitor 1-[(2S)-3-methyl-2-[(2,3,4,5,6-p... 1 0
Neutrophil elastase inhibitor 1-[(2S)-2-[(4-chlorophenyl)sulfo... 1 0
Calpain-1 catalytic subunit and Cathepsin B inhibitor [(3R,5S)... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00302636 CHEMBL168471 Bioactive (2S)-2-[(4-fluorophenyl)sulfonylamino]-3-methyl-N-[(2R)-4-methyl-1-oxopentan-2-yl]butanamide
CFAMM00302638 DNC014771 Investigative Drug SJA-6017

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48680 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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