CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID4113
Family Name Inositol 1,4,5-trisphosphate receptor type 3 Ligand 5'-deoxy-5'-phenyladenophostin A Family
No. of Seeds 11 No. of Other Members 8
Family Centroid CFAMM00302660 Functional Category Investigative Drug
Superfamily Inositol 1,4,5-trisphosphate receptor type 3 Ligand 5'-deoxy-5'-phenyladenophostin A Superfamily
Class Class 1289

Cousin Family NamesSeedsMembers
Cyclin-dependent kinase 2 Inhibitor Seliciclib Family 29 292
P2Y purinoceptor 12 Inhibitor Brilinta Family 1 1
Pigment epithelium-derived factor Inhibitor Adpedr Family 2 112
Adenosine receptor A3 Ligand CF101 Family 24 560
Adenosine receptor A2a Ligand MRE-0094 Family 10 108
Adenosine receptor A1 Ligand SLV320 Family 6 79
GP-531 family 1 33
C-Jun N-terminal kinase Inhibitor CC-930 Family 2 9
Equilibrative nucleoside/nucleobase transporter Inhibitor Nitr... 23 98
Poly [ADP-ribose] polymerase 1 Inhibitor EB-47 Family 17 41
Heat shock protein HSP 90-alpha Inhibitor 8-benzo[1,3]dioxol-,... 5 83
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 2 7
Adenosine receptor A1 and Adenosine receptor A2a Ligand N6-met... 7 72
Adenosine receptor A1 and Adenosine receptor A2a Ligand GW-328... 26 94
Adenosine receptor A1 and Adenosine receptor A2a Ligand N6-met... 21 57
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-[(4-... 15 9
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-(3''... 12 5
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-(3''... 2 2
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-(3''... 2 3
Adenosine receptor A2a and Adenosine receptor A3 Ligand 2-(3''... 8 10
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor SK&F-96... 5 83
Adenosine kinase inhibitor GP683 family 12 7
Adenosine receptor A3 and Adenosine receptor A1 ligand (2S,3S,... 3 0
Adenosine receptor A3 and Adenosine receptor A1 ligand (2R,3S,... 1 2
Uracil nucleotide/cysteinyl leukotriene receptor ligand azane;... 1 0
Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) ... 24 9
Adenosine receptor A3 ligand SureCN6211758 family 5 10
Adenosine receptor A1 and Adenosine receptor A2a ligand (2S,3S... 2 16
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase inh... 7 6
S-methyl-5'-thioadenosine phosphorylase inhibitor SureCN997478... 8 0
Adenosine receptor A3 and Adenosine receptor A2a ligand (1R,2R... 12 17
Adenosine kinase inhibitor N-cyclopropyl-2-[[1-[(2R,3R,4S,5R)-... 4 1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 3 0
Adenosine deaminase inhibitor AGN-PC-00FYYU family 4 5
Adenosine receptor A1 ligand N-[(2R,3R,4R,5R)-5-[6-(cyclopenty... 3 2
Adenosine kinase inhibitor (2R,3R,4R)-2-[4-(2,3-dihydro-1,4-be... 5 2
Adenosine kinase inhibitor 2-[[7-[(2R,3R,4S,5R)-3,4-dihydroxy-... 15 0
Adenosine kinase inhibitor SureCN8320660 family 7 2
Adenosine receptor A3 and Adenosine receptor A1 ligand (2S,3S,... 8 10
Adenosine receptor A3 and Adenosine receptor A1 ligand (2S,3S,... 6 17
Adenosine receptor A3 and Adenosine receptor A1 ligand (2S,3S,... 2 0
Adenosine receptor A3 ligand (1R,2R,3S,4R,5S)-4-[2-[2-(2-chlor... 5 1
Adenosine receptor A1 and Adenosine receptor A2a ligand (2R,3R... 1 2
Adenosine receptor A2b and Adenosine receptor A1 ligand SureCN... 11 4
Tyrosine-protein kinase JAK1 and Non-receptor tyrosine-protein... 7 0
Adenosine receptor A3 and Adenosine receptor A1 ligand (2S,3S,... 7 4
Adenosine receptor A3 ligand (2R,3R,4S)-2-[2-chloro-6-[(3-fluo... 6 7
Adenosine receptor A3 ligand (2R,3R,4S)-2-[6-[(3-bromophenyl)m... 3 0
Adenosine receptor A1 and Adenosine receptor A3 ligand N-benzy... 4 2
Tyrosine-protein kinase JAK1 and Tyrosine-protein kinase JAK2 ... 16 0
Adenosine receptor A1 ligand 2-[4-[[2-[4-[[9-[(3R,4S,5R)-3,4-d... 14 0
Adenosine receptor A1 ligand 3-chloro-N-[(2S,3R,4R,5R)-5-[6-(c... 1 0
Adenosine receptor A1 ligand N-[(2R,3R,4R,5R)-5-[6-(cyclopenty... 3 3
Adenosine receptor A2a and Adenosine receptor A2b ligand Cgs-2... 1 2
P2X purinoceptor 1 and P2X purinoceptor 3 inhibitor [(2R,3R,4R... 1 5
Adenosine receptor A3 and Adenosine receptor A1 ligand (2R,3R,... 1 0
Adenosine receptor A1 ligand (2,5-dioxopyrrolidin-1-yl) 2-[4-[... 3 0
Adenosine receptor A1 ligand (2-bromophenyl)methyl (1S,3R,4S)-... 1 0
Adenosine receptor A3 and Adenosine receptor A2a ligand (1R,2R... 2 0
Adenosine receptor A2a and Adenosine receptor A3 ligand SureCN... 4 3
Adenosine receptor A2a and Adenosine receptor A2b ligand (3S,4... 3 2
Adenosine receptor A2a and Adenosine receptor A2b ligand (3R,4... 7 3
Adenosine receptor A1 and Adenosine receptor A2b ligand (2R,3R... 1 0
P2Y purinoceptor 12 inhibitor [(3aR,4R,6R,6aR)-4-[6-(ethylcarb... 2 4
DNA polymerase III PolC-type and DNA polymerase III subunit al... 11 10
78 kDa glucose-regulated protein inhibitor 4-[[(2R,3S,4R,5R)-5... 1 0
78 kDa glucose-regulated protein and Heat shock cognate 71 kDa... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00302657 CHEMBL604837 Bioactive (3S,4R,5S)-2-[6-amino-2-(2-naphthalen-1-ylethoxy)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
CFAMM00302650 CHEMBL604212 Bioactive (3S,4R,5S)-2-[6-amino-2-(5-phenylpentoxy)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
CFAMM00302656 CHEMBL604836 Bioactive (3S,4R,5S)-2-[6-amino-2-[2-(3-methylphenyl)ethoxy]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
CFAMM00302649 CHEMBL1161891 Bioactive [(2R,3R,4R,5R)-2-(6-aminopurin-9-yl)-4-[(2R,3R,4R,5R,6R)-3-hydroxy-6-(hydroxymethyl)-4,5-diphosphonooxyoxan-2-yl]oxy-5-(2-phenylethyl)oxolan-3-yl] dihydrogen phosphate
CFAMM00302662 CHEMBL606092 Bioactive (3S,4R,5S)-2-[6-amino-2-(2-phenylethoxy)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
CFAMM00302655 CHEMBL1097652 Bioactive [[(2R,3S,4R,5R)-5-[6-amino-2-(2-phenylethynyl)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate;azane
CFAMM00302647 CHEMBL1161892 Bioactive [(2R,3R,4R,5R)-2-(6-aminopurin-9-yl)-4-[(2R,3R,4R,5R,6R)-3-hydroxy-6-(hydroxymethyl)-4,5-diphosphonooxyoxan-2-yl]oxy-5-(3-phenylpropyl)oxolan-3-yl] dihydrogen phosphate
CFAMM00302661 CHEMBL605257 Bioactive (3S,4R,5S)-2-[6-amino-2-(4-phenylbutoxy)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
CFAMM00302654 CHEMBL260203 Bioactive (2R,3R,4S,5R)-2-[6-amino-2-(2-naphthalen-1-ylethoxy)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
CFAMM00302660 DNC014776 Investigative Drug 5'-Deoxy-5'-phenyladenophostin A

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26190 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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