Cousin Family Names | Seeds | Members |
---|
Receptor-type tyrosine-protein kinase FLT3 inhibitor indoline ... | 4 | 151 |
5-hydroxytryptamine receptor 1B ligand triptan Almotriptan Family | 8 | 438 |
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... | 14 | 2769 |
D(2) dopamine receptor and D(1A) dopamine receptor ligand ergo... | 12 | 720 |
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... | 4 | 171 |
Alpha adrenergic receptor ligand ergot alkaloid Dihydroergota... | 7 | 12 |
HIV protease Inhibitor Saquinavir Family | 64 | 428 |
5-hydroxytryptamine receptor Ligand Ramosetron Family | 10 | 219 |
D(1A) dopamine receptor ligand ergot alkaloid Methylergonovine... | 22 | 170 |
D(2) dopamine receptor ligand ergot alkaloid Cabergoline Family | 5 | 74 |
Gastrin/cholecystokinin type B receptor ligand peptide Pentaga... | 26 | 1171 |
5-hydroxytryptamine receptor 3A Ligand Granisetron Family | 26 | 212 |
Somatostatin receptor type 2 ligand octapeptide Octreotide Family | 27 | 172 |
Sodium channel protein type 5 subunit alpha Ligand Disopyramid... | 4 | 352 |
Acetylcholinesterase Inhibitor Tacrine Family | 12 | 515 |
D(2) dopamine receptor Ligand Sertindole Family | 3 | 173 |
Gamma-aminobutyric acid A receptor Ligand Bromazepam Family | 2 | 60 |
Histamine H1 receptor Ligand Triprolidine Family | 19 | 316 |
Indoleamine 2,3-dioxygenase 1 Inhibitor L-tryptophan Family | 8 | 328 |
Bacterial outer membrane Inhibitor Daptomycin Family | 6 | 50 |
Somatostatin receptor type 2 ligand octapeptide Lanreotide Family | 93 | 156 |
Prothrombin Inhibitor Ximelegatran Family | 8 | 157 |
Hepatocyte growth factor receptor Ligand Arq 197 Family | 10 | 400 |
Glycogen synthase kinase-3 beta and Protein kinase C beta type... | 5 | 53 |
Glycogen phosphorylase, muscle form Inhibitor PSN357 Family | 3 | 253 |
Neuromedin-K receptor Ligand SB222200 Family | 17 | 235 |
Cholecystokinin receptor type A Ligand Tarazepide Family | 6 | 323 |
Receptor-type tyrosine-protein kinase FLT3 Inhibitor SU5614 Fa... | 4 | 36 |
Fibroblast growth factor receptor 1 and Aurora kinase B Inhibi... | 4 | 51 |
Substance-P receptor Ligand GSK424887 Family | 8 | 184 |
Poly [ADP-ribose] polymerase 1 Inhibitor AG-14699 Family | 13 | 179 |
Mitogen-activated protein kinase 14 Inhibitor Losmapimod Family | 5 | 154 |
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... | 13 | 242 |
Glutamate receptor AMPA subtype Ligand CX-516 Family | 9 | 24 |
Gamma-aminobutyric acid receptor Ligand E-2007 Family | 7 | 118 |
Growth hormone receptor Ligand EP-51216 Family | 34 | 390 |
D(1B) dopamine receptor Ligand LE-300 Family | 65 | 452 |
Histone deacetylase 1 Inhibitor Panobinostat Family | 5 | 93 |
D(3) dopamine receptor Ligand SB-277011 Family | 13 | 178 |
Protein kinase C alpha type and Protein kinase C beta type Inh... | 16 | 86 |
Substance-P receptor Ligand TAK-637 Family | 18 | 63 |
NS5A protein Inhibitor Bms 790052 Family | 5 | 9 |
Histone deacetylase 1 Inhibitor Resminostat Family | 2 | 5 |
TGF-beta receptor type-1 Ligand LY2157299 Family | 13 | 56 |
JAK Inhibitor Momelotinib Family | 33 | 83 |
Neuropeptide Y receptor type 5 Ligand Npy5ra-972 Family | 6 | 29 |
Gastrin/cholecystokinin type B receptor Ligand PD136450 Family | 53 | 117 |
C-C chemokine receptor type 3 Ligand YM-344031 Family | 19 | 106 |
5-hydroxytryptamine receptor 2A Ligand RP-68303 Family | 7 | 44 |
Lethal factor Inhibitor GM6001 Family | 50 | 435 |
XL-888 family | 16 | 85 |
Cyclin-dependent kinase 5 Inhibitor 9-nitropaullone Family | 2 | 13 |
cGMP-dependent 3',5'-cyclic phosphodiesterase Inhibitor CP-461... | 4 | 34 |
Nicotinic acetylcholine receptor Ligand Epibatidine Family | 36 | 19 |
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand 1-(9h-... | 4 | 25 |
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... | 6 | 17 |
Fibroblast growth factor receptor 2 Ligand Interferon Alfa (if... | 14 | 162 |
Cannabinoid receptor 2 Ligand JWH-167 Family | 25 | 168 |
Somatostatin receptor type 2 Ligand L-054852 Family | 13 | 88 |
5-hydroxytryptamine receptor 2B Ligand Sb 206553 Family | 14 | 21 |
Carbonic anhydrase 2 Inhibitor N-[2-(1h-indol-5-yl)-butyl]-4-s... | 12 | 70 |
Beta-secretase 1 Inhibitor 6-[2-(1h-indol-6-yl)ethyl]pyridin-2... | 10 | 43 |
D(2) dopamine receptor and D(3) dopamine receptor Ligand 4-(4-... | 3 | 15 |
D(2) dopamine receptor and D(3) dopamine receptor Ligand 4-(4-... | 6 | 48 |
Substance-K receptor and Substance-P receptor Ligand L-732138 ... | 8 | 147 |
Cathepsin B and Cathepsin K Inhibitor Z-arg-leu-val-agly-ile-v... | 3 | 19 |
Potassium voltage-gated channel subfamily H member 2 Ligand 5-... | 5 | 14 |
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 8-(3... | 4 | 22 |
Cyclin-dependent kinase 1 and G2/mitotic-specific cyclin-B1 In... | 2 | 0 |
cGMP-inhibited 3',5'-cyclic phosphodiesterase A and Cytochrome... | 9 | 40 |
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor N-(4... | 4 | 21 |
Histone deacetylase 6 Inhibitor N-(quinolin-3-yl)-6-(sulfamoyl... | 4 | 8 |
Acetylcholinesterase and Cholinesterase Inhibitor Lipocrine Fa... | 18 | 36 |
Poly [ADP-ribose] polymerase 1 Inhibitor 1,7,8,9-tetrahydro-1,... | 19 | 64 |
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand C[n... | 12 | 10 |
Melanocortin receptor Ligand Ac-his-dnal(2)-arg-trp-nh2 Family | 112 | 67 |
Cholecystokinin receptor type A Ligand VL-0395 Family | 12 | 117 |
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-methyl-1h... | 24 | 50 |
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-methyl-1h... | 6 | 24 |
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 3-(thiophen... | 9 | 66 |
Platelet-derived growth factor receptor alpha and Platelet-der... | 3 | 3 |
Adenosine receptor A1 and Adenosine receptor A3 Ligand VUF-850... | 28 | 47 |
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Ac-... | 38 | 60 |
Transient receptor potential cation channel subfamily V member... | 6 | 23 |
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-3... | 37 | 1 |
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-2... | 8 | 1 |
D(4) dopamine receptor Ligand ABT-670 Family | 4 | 14 |
Adenosine receptor A3 Ligand 2-benzyl-2h-pyrazolo[3,4-c]quinol... | 3 | 11 |
Microsomal triglyceride transfer protein large subunit Inhibit... | 5 | 9 |
Trypsin Inhibitor 1-benzyl-1h-indole-5-carboxamidine Family | 4 | 3 |
Delta-type opioid receptor Ligand H-poa-ser-gly-phe-leu-thr-oh... | 5 | 12 |
Cannabinoid receptor 1 Ligand N-phenyl-5,6-dip-tolylpyrazine-2... | 11 | 26 |
Cholinesterase Inhibitor 9-[9-(beta-carboline-9-yl)nonyl]-beta... | 7 | 7 |
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand C[c... | 20 | 18 |
Mineralocorticoid receptor and Androgen receptor Ligand WAY-25... | 10 | 26 |
Carbonic anhydrase 2 and Carbonic anhydrase 9 Inhibitor Quinol... | 4 | 13 |
5-hydroxytryptamine receptor 6 Ligand 6-tosyl-1,2,3,4,5,6-hexa... | 4 | 22 |
Poly [ADP-ribose] polymerase 1 Inhibitor 3-ethenylquinoline-8-... | 8 | 4 |
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... | 4 | 33 |
5-hydroxytryptamine receptor 2C Ligand Cyclo[(6-bromotryptopha... | 3 | 17 |
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 5-... | 4 | 10 |
Bifunctional epoxide hydrolase 2 Inhibitor N-(3,3-diphenyl-pro... | 6 | 14 |
Angiotensin-converting enzyme and Endothelin-converting enzyme... | 2 | 10 |
Protein kinase C theta type Inhibitor 4-(3h-indol-4-ylamino)-5... | 2 | 2 |
Kappa-type opioid receptor and Mu-type opioid receptor Ligand ... | 19 | 108 |
Mitogen-activated protein kinase 14 Inhibitor N-(4-fluorobenzy... | 19 | 32 |
Kinesin-like protein KIF11 Inhibitor 9h-carbazole-2-carbaldehy... | 1 | 3 |
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... | 2 | 4 |
Sodium-dependent serotonin transporter Inhibitor 3-(3-aminocyc... | 94 | 23 |
Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor N... | 6 | 10 |
5-hydroxytryptamine receptor 2A and Amine oxidase [flavin-cont... | 10 | 18 |
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand 3-chlo... | 3 | 2 |
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... | 3 | 29 |
Glutamate receptor 1 Ligand Piriqualone Family | 8 | 67 |
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... | 3 | 27 |
Endothelin B receptor Ligand IRL-2500 Family | 34 | 87 |
Vasopressin V1a receptor and Vasopressin V1b receptor Ligand D... | 10 | 19 |
Amine oxidase [flavin-containing] A Inhibitor N-benzyl-1h-pyrr... | 12 | 46 |
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... | 4 | 6 |
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... | 12 | 72 |
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... | 18 | 72 |
Metabotropic glutamate receptor 5 Ligand 3-m-tolyl-1,5-naphthy... | 6 | 10 |
Vasopressin V2 receptor Ligand YM-35278 Family | 33 | 38 |
Acetylcholinesterase and Cholinesterase Inhibitor 7-oxo-7h-dib... | 2 | 3 |
Metabotropic glutamate receptor 1 Ligand (e)-4,4-dimethyl-1-qu... | 2 | 2 |
Acetylcholinesterase and Cholinesterase Inhibitor 3-(2-diethyl... | 12 | 160 |
Melanocortin receptor Ligand Ac-his-dphe(3,4-dicl)-arg-trp-nh2... | 10 | 14 |
Bombesin receptor subtype-3 and Gastrin-releasing peptide rece... | 42 | 7 |
Acetylcholinesterase and Cholinesterase Inhibitor Huprine-tacr... | 62 | 27 |
Choline kinase alpha Inhibitor Bisquinolinium Derivative Family | 10 | 7 |
Substance-K receptor ligand 1-N,2-N-bis[2-(1H-indol-3-yl)ethyl... | 1 | 0 |
Substance-P receptor ligand AGN-PC-01ZIXQ family | 13 | 42 |
Dipeptidyl peptidase 4 inhibitor (1S,3S,5S)-2-[(2S)-2-amino-2-... | 3 | 5 |
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... | 8 | 12 |
Huntingtin and Glycogen synthase kinase-3 beta inhibitor SB 21... | 2 | 4 |
C-C chemokine receptor type 5 ligand AC1LAJEM family | 4 | 14 |
Pol polyprotein inhibitor penicillin deriv. 40 family | 2 | 4 |
Dipeptidyl peptidase 1 inhibitor (2S)-2-amino-N-[(1S)-1-cyano-... | 2 | 14 |
Glycogen synthase kinase-3 beta and Protein kinase C alpha typ... | 3 | 1 |
Glycogen synthase kinase-3 beta and Glycogen synthase kinase-3... | 2 | 1 |
Glycogen synthase kinase-3 beta inhibitor AGN-PC-07ZA4D family | 1 | 0 |
Prolyl endopeptidase inhibitor [(2S,3aS,7aS)-2-(pyrrole-1-carb... | 2 | 0 |
Histone deacetylase 3 and Histone deacetylase 6 inhibitor Tria... | 20 | 37 |
Translocator protein inhibitor AGN-PC-07RE6S family | 1 | 0 |
Gonadotropin-releasing hormone receptor ligand 1-(3-azabicyclo... | 6 | 2 |
Gonadotropin-releasing hormone receptor ligand 1-(3-azabicyclo... | 5 | 0 |
Gonadotropin-releasing hormone receptor ligand 5-[2-[[(2S)-2-[... | 7 | 58 |
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... | 17 | 28 |
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... | 14 | 8 |
Cathepsin L1 inhibitor Bio2_000267 family | 9 | 1 |
Neutrophil collagenase and Stromelysin-3 inhibitor AC1MORIH fa... | 7 | 9 |
Growth hormone secretagogue receptor type 1 ligand 2-amino-N-[... | 1 | 0 |
Growth hormone secretagogue receptor type 1 ligand 2-amino-N-[... | 3 | 0 |
Vascular endothelial growth factor receptor 2 and Receptor-typ... | 7 | 4 |
Substance-P receptor ligand N-[(1S,2R)-2-[[(1R)-1-[methyl-(2-p... | 2 | 0 |
Serine/threonine-protein kinase D1 inhibitor SureCN1424142 family | 13 | 8 |
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... | 2 | 2 |
Caspase-1 inhibitor (3S)-3-[[(2S)-4-[2-(1,2-dimethylindol-3-yl... | 3 | 4 |
Caspase-1 inhibitor (3S)-4-oxo-3-[[(2S)-4-oxo-2-propan-2-yl-4-... | 3 | 0 |
Disintegrin and metalloproteinase domain-containing protein 17... | 2 | 11 |
Prothrombin and Cationic trypsin inhibitor tert-butyl N-[(2R)-... | 4 | 3 |
Sodium-dependent serotonin transporter and Sodium-dependent do... | 10 | 2 |
MAP kinase-activated protein kinase 2 inhibitor CHEMBL1233942 ... | 6 | 0 |
Serine/threonine-protein kinase pim-3 and Serine/threonine-pro... | 4 | 6 |
Prothrombin inhibitor (2S)-N-[(6-carbamimidoylpyridin-3-yl)met... | 2 | 14 |
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... | 11 | 20 |
MAP kinase-activated protein kinase 2 and Mitogen-activated pr... | 5 | 2 |
Histamine H3 receptor ligand AGN-PC-04YWRD family | 5 | 13 |
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... | 4 | 0 |
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... | 1 | 1 |
Somatostatin receptor type 2 ligand tert-butyl (2S)-6-amino-2-... | 1 | 2 |
Cellular tumor antigen p53 and Beta-lactamase inhibitor CHEMBL... | 1 | 36 |
Survival motor neuron protein and Nonstructural protein 1 inhi... | 1 | 18 |
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... | 2 | 0 |
5-hydroxytryptamine receptor 1A ligand 2-[4-(quinolin-2-ylmeth... | 2 | 91 |
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... | 3 | 1 |
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... | 3 | 8 |
Disintegrin and metalloproteinase domain-containing protein 17... | 4 | 0 |
Disintegrin and metalloproteinase domain-containing protein 17... | 3 | 3 |
Growth hormone-releasing hormone receptor ligand ethyl (1S)-1'... | 3 | 2 |
Somatostatin receptor type 2 ligand (2R,3S)-N-[(5-amino-1,3-di... | 2 | 5 |
Mitogen-activated protein kinase 1 and Nonstructural protein 1... | 1 | 33 |
Survival motor neuron protein and Menin inhibitor CHEMBL151109... | 1 | 11 |
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... | 5 | 8 |
Somatostatin receptor type 4 ligand methyl 5-(diaminomethylide... | 2 | 34 |
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... | 2 | 4 |
Cannabinoid receptor 2 ligand [(4R,4aS,8aR)-4-hydroxy-4-phenyl... | 2 | 41 |
Gonadotropin-releasing hormone receptor ligand 1-(7-azabicyclo... | 4 | 4 |
5-hydroxytryptamine receptor 2A and Alpha-1B adrenergic recept... | 10 | 9 |
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... | 2 | 2 |
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... | 3 | 1 |
Serine/threonine-protein kinase D3 and Protein kinase C delta ... | 3 | 0 |
Prothrombin and Trypsin-1 inhibitor 2-[6-methyl-2-oxo-3-(2-pyr... | 4 | 2 |
Glucocorticoid receptor and Mineralocorticoid receptor ligand ... | 9 | 3 |
cGMP-specific 3',5'-cyclic phosphodiesterase and Dual 3',5'-cy... | 4 | 129 |
Glycogen synthase kinase-3 beta and Tyrosine-protein kinase JA... | 1 | 0 |
Acetylcholinesterase inhibitor CHEMBL1651131 family | 6 | 9 |
Ceramide glucosyltransferase inhibitor AGN-PC-07YS0C family | 4 | 3 |
Substance-K receptor ligand N-[1-[[(2R)-5-[4-(oxan-4-ylmethyl)... | 2 | 0 |
Gonadotropin-releasing hormone receptor and Cytochrome P450 3A... | 5 | 1 |
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor 2-... | 18 | 2 |
Sodium-dependent serotonin transporter and Sodium-dependent do... | 1 | 0 |
Interstitial collagenase and Matrilysin inhibitor (2S,3R)-N,2-... | 3 | 1 |
Substance-P receptor ligand N-[(2S)-5-[3,5-bis(trifluoromethyl... | 4 | 6 |
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... | 3 | 2 |
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... | 18 | 3 |
Substance-P receptor and Neuromedin-K receptor ligand SureCN88... | 4 | 14 |
Baculoviral IAP repeat-containing protein 2 and Baculoviral IA... | 1 | 0 |
Histone deacetylase and Histone deacetylase 3 inhibitor (3S,6R... | 2 | 2 |
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... | 5 | 1 |
Renin and Potassium voltage-gated channel subfamily H member 2... | 9 | 2 |
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... | 1 | 0 |
Mitogen-activated protein kinase 9 and MAP kinase-activated pr... | 1 | 0 |
Glycogen synthase kinase-3 beta inhibitor 3-(2-bromoacetyl)-4-... | 1 | 0 |
C-X-C chemokine receptor type 3 ligand (6aR,9R)-N-phenyl-4-(2-... | 5 | 0 |
Smoothened homolog inhibitor (8aS)-N-[2-(3-cyanophenyl)pyridin... | 3 | 4 |
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... | 2 | 0 |
Histone deacetylase 1 inhibitor (E)-N-hydroxy-3-[4-[[2-(2-meth... | 7 | 9 |
Renin inhibitor [2-[(3-fluoro-2-methylphenyl)methyl]-6-methyl-... | 2 | 1 |
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... | 2 | 3 |
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... | 2 | 1 |
Poly [ADP-ribose] polymerase 1 inhibitor CHEMBL186461 family | 2 | 4 |
Cytochrome P450 2D6 and Cytochrome P450 2C19 inhibitor Demethy... | 1 | 4 |
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... | 5 | 0 |
CGMP-dependent protein kinase inhibitor AGN-PC-075XII family | 25 | 7 |
Renin and Potassium voltage-gated channel subfamily H member 2... | 13 | 11 |
Substance-P receptor and Neuromedin-K receptor ligand 2-[3,5-b... | 7 | 0 |
Rho-associated protein kinase 2 and Rho-associated protein kin... | 2 | 6 |
Ribosomal protein S6 kinase alpha-3 inhibitor 1-oxo-N-[1-(pyri... | 5 | 11 |
MAP kinase-activated protein kinase 2 inhibitor 4-fluoro-N-[4-... | 25 | 1 |
Melanin-concentrating hormone receptor 2 ligand N-[(1R)-1'-(9H... | 4 | 1 |
Cannabinoid receptor 1 ligand (2-cyclopentyl-5-prop-2-enyl-3,4... | 3 | 8 |
C-C chemokine receptor type 3 ligand 1-[(1R,2S)-2-[[3-[(4-fluo... | 3 | 2 |
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-009GH... | 8 | 10 |
Melanin-concentrating hormone receptor 1 and Melanin-concentra... | 3 | 1 |
Neuropeptide Y receptor type 5 ligand 2-indol-1-yl-N-[4-[(prop... | 7 | 6 |
Histone deacetylase 6 and Histone deacetylase 1 inhibitor 4-[(... | 3 | 5 |
Substance-P receptor ligand [3,5-bis(trifluoromethyl)phenyl]-[... | 17 | 1 |
High affinity nerve growth factor receptor and BDNF/NT-3 growt... | 4 | 3 |
Oxytocin receptor ligand (3R,6R)-3-(2,3-dihydro-1H-inden-2-yl)... | 20 | 2 |
Egl nine homolog 1 inhibitor 1'-[(3-methylpyridin-2-yl)methyl]... | 6 | 4 |
Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-(4-quinolin-4-ylpi... | 5 | 8 |
Cathepsin K and Cathepsin S inhibitor (2S)-N-(cyanomethyl)-4-m... | 1 | 0 |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B and cAMP-speci... | 2 | 3 |
Cathepsin K and Cathepsin B inhibitor (1R,2R)-N-(1-cyanocyclop... | 10 | 7 |
Probable G-protein coupled receptor 142 ligand (2S)-N-(2-oxo-5... | 2 | 1 |
Glutamate receptor ionotropic, NMDA 2B ligand N-[3-[2-(4-benzy... | 2 | 0 |
Serine/threonine-protein kinase Chk1 inhibitor SureCN5547496 f... | 2 | 1 |
Vascular endothelial growth factor receptor 2 and Angiopoietin... | 14 | 0 |
Renin inhibitor (E)-but-2-enedioic acid;(3S,5R)-5-[4-(2-chloro... | 6 | 8 |
Serine/threonine-protein kinase Chk1 inhibitor SureCN14402832 ... | 6 | 5 |
Serine/threonine-protein kinase Chk1 inhibitor 3-[5-(piperidin... | 1 | 0 |
Serine/threonine-protein kinase Chk1 inhibitor SureCN5547533 f... | 3 | 2 |
Dual specificity protein kinase CLK4 and Mitogen-activated pro... | 1 | 1 |
RAC-beta serine/threonine-protein kinase and 3-phosphoinositid... | 1 | 1 |
RAC-beta serine/threonine-protein kinase and 3-phosphoinositid... | 11 | 4 |
Coagulation factor X inhibitor 3-chloro-N-[(1S,2S)-2-[[4-(2-ox... | 22 | 3 |
Gonadotropin-releasing hormone receptor ligand 5-[2-[[(2S)-2-[... | 2 | 0 |
Gonadotropin-releasing hormone receptor ligand 1-adamantyl-[2-... | 3 | 1 |
Disintegrin and metalloproteinase domain-containing protein 17... | 7 | 9 |
5-hydroxytryptamine receptor 6 and 5-hydroxytryptamine recepto... | 2 | 2 |
Coagulation factor X inhibitor ethyl (3R,4S)-3-[(3-chloro-1H-i... | 5 | 0 |
C-C chemokine receptor type 2 ligand 2-[4-(5-amino-1H-indol-3-... | 3 | 2 |
Tankyrase-1 inhibitor N-[4-[(4S)-5,5-dimethyl-2-oxo-4-phenyl-1... | 3 | 2 |
Gonadotropin-releasing hormone receptor ligand SureCN7899418 f... | 12 | 4 |
Leucine-rich repeat serine/threonine-protein kinase 2 and Plat... | 1 | 0 |
Serine/threonine-protein kinase PLK4 inhibitor (3E)-3-[[3-[(E)... | 5 | 2 |
Orexin receptor type 2 and Orexin receptor type 1 ligand 9-(4,... | 2 | 8 |
Orexin receptor type 2 and Orexin receptor type 1 ligand SureC... | 2 | 0 |
3-oxo-5-alpha-steroid 4-dehydrogenase 2 and 3-oxo-5-alpha-ster... | 2 | 1 |
Phospholipase D1 and Phospholipase D2 inhibitor SureCN10311349... | 2 | 14 |
Histone deacetylase 1 inhibitor (2S)-N'-hydroxy-2-(pyridine-2-... | 3 | 0 |
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor (2... | 2 | 2 |
Somatostatin receptor type 1 and Somatostatin receptor type 2 ... | 2 | 18 |
C-C chemokine receptor type 2 ligand SureCN5947024 family | 11 | 0 |
CGMP-dependent protein kinase inhibitor methyl 2-[[4-[5-(4-flu... | 6 | 1 |
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... | 2 | 1 |
Renin inhibitor tert-butyl N-[1-[[1-[[1-cyclohexyl-4,4-difluor... | 5 | 0 |
Proteinase-activated receptor 1 and Prothrombin ligand (2S)-N-... | 3 | 23 |
Gonadotropin-releasing hormone receptor ligand 1-[2-(3,5-dimet... | 3 | 0 |
CGMP-dependent protein kinase inhibitor 1-[4-acetyl-3-[[4-[5-(... | 2 | 0 |
Substance-P receptor ligand (4R)-N-[(2R)-1-[benzyl(methyl)amin... | 8 | 5 |
Bombesin receptor subtype-3 ligand SureCN13887096 family | 3 | 1 |
Platelet-activating factor receptor ligand (1-ethylindol-3-yl)... | 17 | 13 |
Platelet-activating factor receptor ligand N,N-diethyl-3-[(4R)... | 11 | 0 |
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... | 2 | 2 |
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... | 2 | 2 |
Platelet-activating factor receptor ligand (4R)-N-(3-benzoylph... | 2 | 1 |
Cyclin-dependent kinase 2 inhibitor SureCN6589205 family | 2 | 2 |
Neuromedin-B receptor and Gastrin-releasing peptide receptor l... | 6 | 4 |
Stromelysin-3 and Neutrophil collagenase inhibitor AGN-PC-074N... | 3 | 1 |
Neuromedin-B receptor and Gastrin-releasing peptide receptor l... | 2 | 0 |
Substance-P receptor and Substance-K receptor ligand N-methyl-... | 2 | 2 |
Histone deacetylase 1 inhibitor AGN-PC-0456JP family | 1 | 0 |
Somatostatin receptor type 2 ligand tert-butyl (2S)-6-amino-2-... | 3 | 1 |
Gonadotropin-releasing hormone receptor ligand methyl 4-[2-[[(... | 2 | 1 |
Telomerase reverse transcriptase inhibitor N-[9-(4-aminoanilin... | 1 | 11 |
Growth factor receptor-bound protein 2 ligand [4-[(2S)-2-aceta... | 5 | 2 |
Angiopoietin-1 receptor and Vascular endothelial growth factor... | 1 | 0 |
KiSS-1 receptor ligand SureCN5132924 family | 2 | 4 |
Melatonin receptor type 1A and Melatonin receptor type 1C liga... | 1 | 0 |
Gonadotropin-releasing hormone receptor ligand 1-[2-(3,5-dimet... | 2 | 0 |
C-X-C chemokine receptor type 2 and Cytochrome P450 2C9 ligand... | 1 | 7 |
Gonadotropin-releasing hormone receptor ligand 1-(7-azabicyclo... | 2 | 0 |
72 kDa type IV collagenase and Interstitial collagenase inhibi... | 1 | 1 |
Sodium-dependent serotonin transporter and D(2) dopamine recep... | 1 | 0 |
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... | 4 | 0 |
Somatostatin receptor type 4 and Somatostatin receptor type 5 ... | 3 | 4 |
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... | 5 | 0 |
Cytochrome P450 2C9 inhibitor AGN-PC-04XDND family | 1 | 3 |
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... | 3 | 4 |
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... | 2 | 4 |
CGMP-dependent protein kinase inhibitor AGN-PC-078XQ0 family | 1 | 1 |
Melanin-concentrating hormone receptor 1 ligand SureCN4917950 ... | 3 | 5 |
5-hydroxytryptamine receptor 7 ligand AGN-PC-00PFK0 family | 1 | 0 |
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... | 2 | 0 |
Interstitial collagenase and Stromelysin-1 inhibitor CHEMBL887... | 1 | 0 |
Serine/threonine-protein kinase Chk1 inhibitor SureCN6080935 f... | 1 | 0 |
Neprilysin inhibitor AGN-PC-073PUZ family | 1 | 0 |
Receptor-interacting serine/threonine-protein kinase 1 ligand ... | 1 | 11 |
Peptide deformylase and Peptide deformylase 1A, chloroplastic/... | 1 | 1 |
Insulin receptor ligand 2,5-dihydroxy-3-(1H-indol-3-yl)-6-phen... | 1 | 0 |
Coagulation factor X inhibitor (3R,4R)-3-N-[2-fluoro-4-(2-oxop... | 1 | 0 |
Protein-glutamine gamma-glutamyltransferase 2 inhibitor SureCN... | 2 | 2 |
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand N-(1-... | 1 | 0 |
Cytochrome P450 2C19 and Cytochrome P450 3A4 inhibitor (E)-3-[... | 4 | 0 |
Prostaglandin D2 receptor 2 ligand AGN-PC-00QBAU family | 1 | 24 |
Histone deacetylase 1 inhibitor N-[(2S)-1,8-dioxo-1-[2-(2-phen... | 2 | 0 |
Tyrosine-protein kinase JAK3 inhibitor (3Z)-5-pyridin-3-yl-3-(... | 1 | 0 |
Cyclin-dependent kinase 2 inhibitor pyrrollylactam indolinone ... | 1 | 0 |
Proto-oncogene Wnt-3 inhibitor CHEMBL563202 family | 2 | 0 |
2,3,6,7-tetrahydropyrazino[1',2':1,2]pyrido[3,4-b]indole-1,4(1... | 3 | 0 |
6-(3-nitrophenyl)-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyri... | 16 | 0 |
NP Agn-pc-099dao Family | 2 | 0 |
Statistics of CFAM Database |
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes. |
How to cite our database |
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering.
Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
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Last update by |
2014.08.29
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