CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID4161
Family Name AMP-activated protein kinase Inhibitor 4-(3-bromopyrazolo[1,5-a]pyrimidin-6-yl)phenol Family
No. of Seeds 1 No. of Other Members 8
Family Centroid CFAMM00303546 Functional Category Investigative Drug
Superfamily AMP-activated protein kinase and Dihydroorotate dehydrogenase Binder Superfamily
Class Class 3008

Cousin Family NamesSeedsMembers
Corticotropin-releasing factor receptor 1 Ligand CRF-1 Antagon... 29 421
Hepatocyte growth factor receptor Ligand Amg 208 Family 20 236
Tyrosine kinase Inhibitor PKI166 Family 17 198
Vascular endothelial growth factor receptor 2 Ligand L00002164... 6 23
Corticotropin-releasing factor receptor 1 Ligand BMS-561388 Fa... 10 16
Serine/threonine-protein kinase B-raf inhibitor SureCN1015955 ... 17 18
Serine/threonine-protein kinase B-raf inhibitor AGN-PC-072YMN ... 7 11
Serine/threonine-protein kinase B-raf inhibitor 3-[7-[4-[[(3R)... 6 7
Serine/threonine-protein kinase Chk2 and Serine/threonine-prot... 3 6
Proto-oncogene tyrosine-protein kinase Src and Tyrosine-protei... 12 8
DNA-(apurinic or apyrimidinic site) lyase and Ras-related prot... 1 5
Proto-oncogene tyrosine-protein kinase Src and Epidermal growt... 9 9
Calmodulin-domain protein kinase 1 and Tyrosine-protein kinase... 5 5
Hepatocyte growth factor receptor ligand 4-[(6-phenyl-[1,2,4]t... 3 6
Cyclin-dependent kinase 2 and Glycogen synthase kinase-3 beta ... 1 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00303546 DNC014890 Investigative Drug 4-(3-bromopyrazolo[1,5-a]pyrimidin-6-yl)phenol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27276 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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