CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID4167
Family Name Neuronal acetylcholine receptor subunit beta-2 Ligand ABT-594 Family
No. of Seeds 4 No. of Other Members 5
Family Centroid CFAMM00303567 Functional Category Investigative Drug
Superfamily Neuronal acetylcholine receptor subunit beta-2 Ligand ABT-594 Superfamily
Class Class 2393

Cousin Family NamesSeedsMembers
Acetylcholinesterase Inhibitor Pyridostigmine Family 5 197
Amyloid beta A4 protein Inhibitor Florbetapir F-18 Family 8 265
Calcium-activated potassium channel subunit alpha-1 Ligand AVE... 3 284
Nicotinic acetylcholine receptor Ligand AZD0328 Family 11 97
Neuronal acetylcholine receptor subunit alpha-4 Ligand Isproni... 49 172
5-hydroxytryptamine receptor 1A and D(3) dopamine receptor Lig... 9 115
Nicotinic acetylcholine receptor Ligand Dianicline Family 6 13
Reverse transcriptase Inhibitor 3'thiacytidine Family 4 29
Tissue-type plasminogen activator Inhibitor N-(7-benzyloxy-iso... 4 37
D(2) dopamine receptor Ligand SLV-314 Family 19 69
Metabotropic glutamate receptor 5 Ligand (3-ethoxy-pyridin-2-y... 3 12
Peptidyl-prolyl cis-trans isomerase A Inhibitor 3-[3-(3-benzyl... 3 34
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 4 35
RAC-gamma serine/threonine-protein kinase Inhibitor A-443654 F... 67 59
5-hydroxytryptamine receptor 2A and Amine oxidase [flavin-cont... 4 32
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 3 24
Fatty-acid amide hydrolase 1 Inhibitor Pyridin-3-yl 4-butoxybe... 10 5
Metabotropic glutamate receptor 5 Ligand 7-(3,5-dimethoxypheny... 2 7
Cannabinoid receptor 1 Ligand 1-(2-morpholinoethyl)-1h-indol-3... 8 46
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 7 1
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 3
Cellular tumor antigen p53 and DNA polymerase beta inhibitor C... 1 15
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 8 8
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 11 4
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 2 4
RAC-alpha serine/threonine-protein kinase and cAMP-dependent p... 3 0
Neuronal acetylcholine receptor subunit alpha-2 and Neuronal a... 6 1
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 7 2
Neuronal acetylcholine receptor subunit beta-2 and Neuronal ac... 5 0
Histamine H3 receptor and Sodium-dependent serotonin transport... 3 2
Potassium voltage-gated channel subfamily KQT member 2 ligand ... 3 4
Histamine H3 receptor and Sodium-dependent serotonin transport... 2 0
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 5 13
Metabotropic glutamate receptor 5 and Cytochrome P450 1A2 liga... 1 1
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 2 0
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 2 2
Bifunctional epoxide hydrolase 2 and Voltage-dependent L-type ... 2 1
Neuronal acetylcholine receptor subunit alpha-3 and Neuronal a... 4 1
Sodium-dependent noradrenaline transporter and Sodium-dependen... 1 0
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 1 1
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 6 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00303560 CHEMBL97502 Bioactive 5-(azetidin-2-ylmethoxy)-2-chloro-3-[(E)-2-pyridin-4-ylethenyl]pyridine
CFAMM00303559 CHEMBL333162 Bioactive (2R)-1-[6-chloro-5-[(E)-2-pyridin-4-ylethenyl]pyridin-3-yl]oxy-N-methylpropan-2-amine
CFAMM00303564 CHEMBL80040 Bioactive 5-[[(2S)-azetidin-2-yl]methoxy]-2-chloro-3-[(E)-2-pyridin-4-ylethenyl]pyridine
CFAMM00303567 DNC014907 Investigative Drug ABT-594

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27698 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543