CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID417
Family Name Glucose-6-phosphate translocase Inhibitor Mumbaistatin Family
No. of Seeds 3 No. of Other Members 11
Family Centroid CFAMM00190838 Functional Category Investigative Drug with Human Metabolite & Natural Product
Superfamily Indoleamine 2,3-dioxygenase 1 and Glucose-6-phosphate translocase Binder Superfamily
Class Class 776

Cousin Family NamesSeedsMembers
DNA binder anthracycline analog Doxorubicin family 9 32
Retinoic acid receptor Ligand naphthoic acid derivative Adapal... 2 264
Prostaglandin G/H synthase 2 Inhibitor Diflunisal Family 7 421
Retinoid X receptor Ligand Bexarotene Family 7 492
Prostaglandin G/H synthase 2 Inhibitor Nabumetone Family 4 267
Signal transducer and activator of transcription 3 Inhibitor A... 5 249
Estrogen receptor beta Ligand Conjugated Estrogens Family 12 210
Rotenone family 16 107
Danthron family 11 141
Leukotriene B4 receptor 1 Ligand LY293111 Family 24 79
Mitogen-activated protein kinase 12 Inhibitor SCIO-469 Family 1 7
Substance-P receptor Ligand CI-1021 Family 1 0
Interleukin-1 beta Inhibitor Diacerein Family 3 77
Apoptosis regulator Bcl-2 Inhibitor Gossypol Family 1 9
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 Ligand... 4 26
Aromatase and DNA-dependent protein kinase catalytic subunit I... 6 19
Estrogen receptor beta Ligand 3,6-dihydroxy-2-(4-hydroxy-pheny... 2 23
Phospholipase A2 Inhibitor 3,9-dihydroxy-2,10-diprenylpterocap... 9 25
Oestrogen receptor and Estrogen receptor beta Ligand 6-(4-hydr... 30 63
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 2 56
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 9 81
Oestrogen receptor and Estrogen receptor beta Ligand 3,8-dihyd... 20 57
Tyrosine-protein phosphatase non-receptor type 1 Ligand Licoag... 9 32
Cytosolic phospholipase A2 Inhibitor [6,3''']biflavone Family 5 5
Estradiol 17-beta-dehydrogenase 1 Inhibitor 3-(6-hydroxy-2-nap... 7 9
DNA topoisomerase 2-beta Inhibitor Demethylzeylasterone Family 1 2
MO15-related protein kinase Pfmrk Inhibitor WR-289012 Family 2 17
Cannabinoid receptor 2 Ligand 2-(2-methoxybenzyl)-3h-benzo[f]c... 6 32
Arachidonate 12-lipoxygenase, 12S-type and Arachidonate 15-lip... 3 7
Indoleamine 2,3-dioxygenase 1 Inhibitor 2-hydroxygarvin A Family 2 2
Indoleamine 2,3-dioxygenase 1 Inhibitor Garveatin E Family 2 0
NAD(P)H dehydrogenase [quinone] 1 Inhibitor 4-hydroxy-3-(2-nap... 12 1
Tyrosine-protein phosphatase non-receptor type 1 Ligand Kuwano... 3 3
Histone deacetylase 1 Inhibitor Gymnochrome E Family 1 0
Arachidonate 5-lipoxygenase Inhibitor 4,5-dimethoxy-10h-anthra... 1 4
Protein farnesyltransferase subunit beta Inhibitor Cylindrol A... 3 43
Prostaglandin G/H synthase 2 Inhibitor 3,4-dibenzyloxy-2'-hydr... 7 40
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 14
Protein kinase C beta type and Protein kinase C eta type inhib... 1 0
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 2 7
Thromboxane A2 receptor ligand AGN-PC-003UTI family 1 0
Steryl-sulfatase inhibitor (8R,9S,13S,14S,17R)-17-benzyl-3,17-... 1 1
Induced myeloid leukemia cell differentiation protein Mcl-1 an... 6 13
Peroxisome proliferator-activated receptor gamma and Peroxisom... 1 2
Solute carrier organic anion transporter family member 1B1 and... 1 0
Sterol O-acyltransferase 1 and Sterol O-acyltransferase 2 inhi... 1 5
Aldehyde dehydrogenase, cytosolic 1 and Aldehyde dehydrogenase... 2 0
72 kDa type IV collagenase inhibitor [(2S,3S,4R)-4-(4,5-dihydr... 1 0
Benzopyrans Metabolite (-)-trans-3,4-Dihydro-4,8-dihydroxy-3-m... 1 0
Acenes Metabolite 3-Hydroxy-9-(4-hydroxyphenyl)-1H,3H-naphtho[... 1 0
Acenes Metabolite Musanolone D Family 2 1
6a,7,8,12a-tetrahydroxy-3-methyl-2,3,4,5,6,7-hexahydrobenzo[a]... 6 0
2,5,8-triacetyloxy-3,4-dioxonaphthalen-1-olate NP Agn-pc-094ek... 1 0
NP Ethyl 5-(tert-butyl)-3-oxo-8,9,10,11-tetrahydro-3h-benzofur... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00190874 DNC007823 Investigative Drug NSC-292213
CFAMM00190870 DNC007403 Investigative Drug MAGGIEMYCIN
CFAMM00190838 DNC000969 Investigative Drug Mumbaistatin

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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