CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID4181
Family Name Histamine H1 receptor and Arachidonate 5-lipoxygenase Ligand N-hydroxycarbamate Derivative Family
No. of Seeds 5 No. of Other Members 6
Family Centroid CFAMM00303828 Functional Category Investigative Drug
Superfamily Histamine H1 receptor and Arachidonate 5-lipoxygenase Ligand N-hydroxycarbamate Derivative Superfamily
Class Class 837

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 2A Ligand Pimavanserin Family 4 23
Histamine H3 receptor Ligand A-349821 Family 49 228
Orexin receptor type 1 and Orexin receptor type 2 ligand [(2S)... 3 1
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 28
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 6
Bifunctional epoxide hydrolase 2 and Cytochrome P450 2C9 inhib... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00303834 CHEMBL179590 Bioactive AGN-PC-007VJC
CFAMM00303831 CHEMBL366925 Bioactive methyl N-[4-[4-[4-[4-[bis(4-fluorophenyl)methyl]piperazin-1-yl]butoxy]phenyl]but-3-ynyl]-N-hydroxycarbamate
CFAMM00303837 CHEMBL180233 Bioactive propan-2-yl N-[4-[4-[4-[4-[bis(4-fluorophenyl)methyl]piperazin-1-yl]butoxy]phenyl]but-3-ynyl]-N-hydroxycarbamate
CFAMM00303829 CHEMBL444083 Bioactive 1-[4-[4-[4-[4-[bis(4-fluorophenyl)methyl]piperazin-1-yl]butoxy]phenyl]but-3-ynyl]-1-hydroxyurea
CFAMM00303836 CHEMBL181085 Bioactive 2-methylpropyl N-[4-[4-[4-[4-[bis(4-fluorophenyl)methyl]piperazin-1-yl]butoxy]phenyl]but-3-ynyl]-N-hydroxycarbamate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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