CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID4193
Family Name Neuropeptide Y receptor type 1 Ligand N-arylpiperazine Derivative Family 2
No. of Seeds 5 No. of Other Members 4
Family Centroid CFAMM00303957 Functional Category Investigative Drug
Superfamily Neuropeptide Y receptor type 1 Binder Superfamily
Class Class 3031

Cousin Family NamesSeedsMembers
Integrin alpha-4 Inhibitor R1295 Family 18 59
Neuropeptide Y receptor type 1 Ligand BMS-193885 Family 3 11
Substance-K receptor Ligand MEN-14933 Family 13 154
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Neuropeptide Y receptor type 1 Ligand N-arylpiperazine Derivat... 13 22
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 1 0
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 2
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 0
Prelamin-A/C and Survival motor neuron protein inhibitor CHEMB... 1 7


External ID

Functional Category

Molecule Name

CFAMM00303961 CHEMBL364380 Bioactive dimethyl 4-[3-[[N-cyano-N'-[2-[[1-(2-hydroxyphenyl)piperidin-4-yl]amino]ethyl]carbamimidoyl]amino]phenyl]-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
CFAMM00303966 CHEMBL187555 Bioactive AGN-PC-008SEJ
CFAMM00303955 CHEMBL31913 Bioactive SureCN8901738
CFAMM00303963 CHEMBL360205 Bioactive AGN-PC-075H6D
CFAMM00303962 CHEMBL187620 Bioactive AGN-PC-0068FF

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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