CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID4227
Family Name Cannabinoid receptor 1 Ligand 1-(4-chlorophenyl)-2-(2,4-dichlorophenyl)-5-(methylsulfinyl)-n-(piperidin-1-yl)- 1h-imidazole-4-carboxamide (enantiomeric Mix) Family
No. of Seeds 18 No. of Other Members 41
Family Centroid CFAMM00304638 Functional Category Investigative Drug
Superfamily Cannabinoid receptor 1 Ligand 1-(4-chlorophenyl)-2-(2,4-dichlorophenyl)-5-(methylsulfinyl)-n-(piperidin-1-yl)- 1h-imidazole-4-carboxamide (enantiomeric Mix) Superfamily
Class Class 3039

Cousin Family NamesSeedsMembers
Gamma-aminobutyric acid A receptor Ligand imidazopyridine deri... 5 644
Cannabinoid receptor 1 Ligand AZD2207 Family 18 48
Cannabinoid receptor 1 Ligand CP-945598 Family 18 173
RAC-gamma serine/threonine-protein kinase Inhibitor AZD5363 Fa... 35 69
D(4) dopamine receptor Ligand L-745,870 Family 30 205
Adenosine receptor A3 Ligand 1-benzyl-1h-1,3,4b,9-tetraaza-flu... 19 165
Proto-oncogene tyrosine-protein kinase Src Inhibitor BMS-27970... 41 59
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 8 12
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 1 0
Adenosine receptor A1 ligand SureCN10614388 family 5 1
Tyrosine-protein kinase BTK and Tyrosine-protein kinase Lyn in... 7 7
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 9 inhibitor AG... 5 4
Dipeptidyl peptidase 9 and Dipeptidyl peptidase 8 inhibitor Su... 16 5
Dipeptidyl peptidase 8 and Dipeptidyl peptidase 4 inhibitor Su... 5 13
Melanin-concentrating hormone receptor 1 and Potassium voltage... 8 27
Inositol monophosphatase 1 and 15-hydroxyprostaglandin dehydro... 1 0
Prelamin-A/C and Cellular tumor antigen p53 inhibitor CHEMBL16... 1 7
Bile acid receptor and Potassium voltage-gated channel subfami... 2 1
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 18
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 6 14
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand AGN-P... 2 0
Cannabinoid receptor 1 ligand AGN-PC-03I5TW family 3 12
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 2 1
Cannabinoid receptor 1 ligand SureCN675796 family 5 1
Metabotropic glutamate receptor 5 ligand [2-[6-(3-chlorophenyl... 1 1
Cannabinoid receptor 1 ligand 1-(4-chlorophenyl)-2-(2,4-dichlo... 2 1
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 3 13
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 10 14
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 5 8
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 1 0
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 3 0
Coagulation factor X and Prothrombin inhibitor 2-carboxyindole... 2 8
C-X-C chemokine receptor type 3 ligand 5-[(3S)-4-[1-(4-chlorob... 6 0
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 5 4
Sodium- and chloride-dependent glycine transporter 1 and Sodiu... 4 8
5-hydroxytryptamine receptor 4 and 5-hydroxytryptamine recepto... 1 1
Glycogen synthase kinase-3 beta inhibitor N-[2-[4-(ethylsulfon... 3 1
P2X purinoceptor 7 inhibitor SureCN109432 family 10 28
P2X purinoceptor 7 inhibitor SureCN113576 family 2 1
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 6 5
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 1 2
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 5 0
Melanocortin receptor 4 ligand AGN-PC-076AMO family 17 8
Tyrosine-protein kinase Lck and Proto-oncogene tyrosine-protei... 3 0
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 0
Nitric oxide synthase, inducible inhibitor N-[(4-chlorophenyl)... 2 1
Cannabinoid receptor 1 ligand N-(3,3a,4,5,6,6a-hexahydro-1H-cy... 2 1
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 2 1
Histamine H3 receptor ligand SureCN1382602 family 6 0
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 2 0
Platelet-derived growth factor receptor beta and Fibroblast gr... 10 0
Cannabinoid receptor 1 ligand AGN-PC-077JWI family 7 1
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand AGN-P... 1 1
Sonic hedgehog protein and Cytochrome P450 2C9 inhibitor AGN-P... 1 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand SureC... 9 0
DNA-(apurinic or apyrimidinic site) lyase and Retinal dehydrog... 1 2
Centromere-associated protein E inhibitor 5-bromo-N-[(3,4-dich... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00304604 CHEMBL368749 Bioactive SureCN4511060
CFAMM00304631 CHEMBL1088507 Bioactive AGN-PC-07ZFOQ
CFAMM00304645 CHEMBL369205 Bioactive SureCN4508279
CFAMM00304597 CHEMBL1088222 Bioactive SureCN675249
CFAMM00304590 CHEMBL174163 Bioactive SureCN4498236
CFAMM00304616 CHEMBL369072 Bioactive SureCN4499062
CFAMM00304630 CHEMBL1088506 Bioactive AGN-PC-07ZFOP
CFAMM00304596 CHEMBL1088223 Bioactive 1-(4-CHLOROPHENYL)-2-(2,4-DICHLOROPHENYL)-5-(METHYLSULFINYL)-N-(PIPERIDIN-1-YL)-1H-IMIDAZOLE-4-CARBOXAMIDE (ENANTIOMERIC MIX)
CFAMM00304622 CHEMBL427497 Bioactive SureCN6104864
CFAMM00304628 CHEMBL1088221 Bioactive AGN-PC-03I5VB
CFAMM00304643 CHEMBL175478 Bioactive SureCN675659
CFAMM00304614 CHEMBL177990 Bioactive SureCN675644
CFAMM00304594 CHEMBL426585 Bioactive SureCN676438
CFAMM00304607 CHEMBL583855 Bioactive SureCN762432
CFAMM00304620 CHEMBL436471 Bioactive AGN-PC-007UBQ
CFAMM00304613 CHEMBL15399 Bioactive SureCN675052
CFAMM00304593 CHEMBL1088349 Bioactive SureCN676071
CFAMM00304599 CHEMBL1088220 Bioactive AGN-PC-03I5VW

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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