CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID4230
Family Name Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand (2r)-n-(6-(4-chlorophenyl)-7-(2,4-dichlorophenyl)-2,2-dimethyl-3,4-dihydro-2h-py Rano[2,3-b]pyridin-4-yl)-2-hydroxypropanamide (enantiomeric Mix) Family
No. of Seeds 18 No. of Other Members 30
Family Centroid CFAMM00304703 Functional Category Investigative Drug
Superfamily Cannabinoid receptor 2 and Cannabinoid receptor 1 Binder Superfamily 5
Class Class 3040

Cousin Family NamesSeedsMembers
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand AGN-P... 3 6
Cannabinoid receptor 1 ligand N-[(4S)-6-(4-chlorophenyl)-7-(2,... 12 0
Cannabinoid receptor 1 and Potassium voltage-gated channel sub... 1 0
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 5 1
Cannabinoid receptor 1 ligand SureCN5355779 family 16 8
Cannabinoid receptor 1 ligand SureCN5354461 family 4 0
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 3 0
Beta-secretase 1 and Cathepsin D inhibitor N-[(2S,3R)-4-[[(4S)... 34 23
Beta-secretase 1 inhibitor N-[(2S,3R)-1-(1,3-benzodioxol-5-yl)... 3 5
Nociceptin receptor and Mu-type opioid receptor ligand N-[[(1S... 2 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00304742 CHEMBL247910 Bioactive SureCN5355321
CFAMM00304722 CHEMBL1086493 Bioactive AGN-PC-04VEZG
CFAMM00304735 CHEMBL1083016 Bioactive N-(6-(4-CHLOROPHENYL)-7-(2,4-DICHLOROPHENYL)-2,2-DIMETHYL-3,4-DIHYDRO-2H-PYRANO[2,3-B]PYRIDIN-4-YL)-3-HYDROXY-2,2-DIMETHYLPROPANAMIDE (ENANTIOMERIC MIX)
CFAMM00304714 CHEMBL1083619 Bioactive (2R)-N-(7'-(2-CHLOROPHENYL)-6'-(4-CHLOROPHENYL)-3',4'-DIHYDROSPIRO[CYCLOHEXANE-1,2'-PYRANO[2,3-B]PYRIDINE]-4'-YL)-2-HYDROXYPROPANAMIDE (ENANTIOMERIC MIX)
CFAMM00304733 CHEMBL1083014 Bioactive N-(6-(4-CHLOROPHENYL)-7-(2,4-DICHLOROPHENYL)-2,2-DIMETHYL-3,4-DIHYDRO-2H-PYRANO[2,3-B]PYRIDIN-4-YL)-2-HYDROXYACETAMIDE (ENANTIOMERIC MIX)
CFAMM00304746 CHEMBL1095990 Bioactive SureCN1405057
CFAMM00304706 CHEMBL1097456 Bioactive N-[6-(4-CHLOROPHENYL)-7-(2,4-DICHLOROPHENYL)-2,2-DIMETHYL-3,4-DIHYDRO-2H-PYRANO[2,3-B]PYRIDINE-4-YL]-4,4,4-TRIFLUORO-3-HYDROXYBUTANAMIDE (DIASTEREOMERIC MIX)
CFAMM00304732 CHEMBL1095159 Bioactive AGN-PC-07ZFCA
CFAMM00304738 CHEMBL1083646 Bioactive (2R)-N-(6-(4-CHLOROPHENYL)-7-(2,4-DICHLOROPHENYL)-2,2-DIMETHYL-3,4-DIHYDRO-2H-PYRANO[2,3-B]PYRIDIN-4-YL)-2-HYDROXYPROPANAMIDE (ENANTIOMERIC MIX)
CFAMM00304705 CHEMBL1083025 Bioactive N-(6-(4-CHLOROPHENYL)-7-(2,4-DICHLOROPHENYL)-2,2-DIMETHYL-3,4-DIHYDRO-2H-PYRANO[2,3-B]PYRIDIN-4-YL)-3-HYDROXYPROPANAMIDE (ENANTIOMERIC MIX)
CFAMM00304744 CHEMBL1084820 Bioactive (2S)-N-(7'-(2-CHLOROPHENYL)-6'-(4-CHLOROPHENYL)-3',4'-DIHYDROSPIRO[CYCLOHEXANE-1,2'-PYRANO[2,3-B]PYRIDINE]-4'-YL)-2-HYDROXYPROPANAMIDE (ENANTIOMERIC MIX)
CFAMM00304724 CHEMBL1086494 Bioactive AGN-PC-04VEZH
CFAMM00304717 CHEMBL1094847 Bioactive AGN-PC-04VD5B
CFAMM00304730 CHEMBL1097455 Bioactive AGN-PC-07ZFBI
CFAMM00304723 CHEMBL1095211 Bioactive N-[(4R)-6-(4-chlorophenyl)-7-(2,4-dichlorophenyl)-2,2-dimethyl-3,4-dihydropyrano[2,3-b]pyridin-4-yl]-4,4,4-trifluoro-3-hydroxy-3-(trifluoromethyl)butanamide
CFAMM00304749 CHEMBL1085566 Bioactive N-(7'-(2-CHLOROPHENYL)-6'-(4-CHLOROPHENYL)-3',4'-DIHYDROSPIRO[CYCLOHEXANE-1,2'-PYRANO[2,3-B]PYRIDINE]-4'-YL)-2-HYDROXY-2-METHYLPROPANAMIDE (ENANTIOMERIC MIX)
CFAMM00304701 CHEMBL1094521 Bioactive SureCN1404748
CFAMM00304716 CHEMBL1095499 Bioactive AGN-PC-07ZFAE

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48711 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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