CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID4239
Family Name Kappa-type opioid receptor Ligand Morphinan Cyclic Imine Analogue Family 2
No. of Seeds 20 No. of Other Members 0
Family Centroid CFAMM00304890 Functional Category Investigative Drug
Superfamily opioid receptor ligand opiate Codeine Buprenorphine Oxymorphone Superfamily
Class Class 66

Cousin Family NamesSeedsMembers
Delta-type opioid receptor ligand opiate analog Codeine Family 15 184
u-type opioid receptor ligand opiate analog Buprenorphine Family 78 234
u-type opioid receptor ligand opiate opiate analog Oxymorphone... 22 105
Sigma non-opioid intracellular receptor 1 ligand opiate Dextro... 9 33
D(1B) dopamine receptor Ligand Apomorphine Family 30 271
Neuronal acetylcholine receptor subunit alpha-2 Ligand Metocur... 18 169
Synaptic vesicular amine transporter Inhibitor Tetrabenazine F... 13 425
Kappa-type opioid receptor Ligand Dezocine Family 36 46
Oestrogen receptor Ligand Lasofoxifene Family 19 152
Nalfurafine Hcl family 33 107
Arachidonate 5-lipoxygenase Inhibitor Bw A360C Family 12 8
Peptide deformylase, mitochondrial Inhibitor Tylophorinidine F... 7 1
Tumor necrosis factor Inhibitor Y-39041 Family 9 51
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 18 25
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 32 30
D(2) dopamine receptor and D(1A) dopamine receptor Ligand 3-br... 2 1
5-hydroxytryptamine receptor 2A and D(1A) dopamine receptor Li... 8 33
Squalene synthase Inhibitor 3-[7'-(methoxy)-napht-2'-yl]-quinu... 53 30
Delta-type opioid receptor Ligand 6-cinnamoyl-n-methylstephasu... 3 0
Delta-type opioid receptor Ligand Longanine Family 3 0
Mu-type opioid receptor Ligand Cyprodime Family 12 8
Tubulin beta chain Inhibitor Colchinol Family 3 109
Kappa-type opioid receptor and Mu-type opioid receptor Ligand ... 6 1
D(2) dopamine receptor and Sodium-dependent dopamine transport... 6 10
D(2) dopamine receptor and D(1A) dopamine receptor Ligand 3-ch... 2 0
Sodium-dependent dopamine transporter Inhibitor Secocularidine... 3 9
Kappa-type opioid receptor and Mu-type opioid receptor Ligand ... 16 10
Kappa-type opioid receptor Ligand Morphinan Cyclic Imine Analo... 3 1
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 2 1
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 3 0
Mu-type opioid receptor and Sigma non-opioid intracellular rec... 10 20
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 4 0
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 2 8
Mu-type opioid receptor ligand Morphine-6-glucuronide family 7 1
D(1A) dopamine receptor and D(3) dopamine receptor ligand N,N-... 3 1
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 3 0
Delta-type opioid receptor and Kappa-type opioid receptor liga... 6 0
D(2) dopamine receptor and D(1A) dopamine receptor ligand ISOM... 2 5
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 8 2
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 18 1
Delta-type opioid receptor and Kappa-type opioid receptor liga... 2 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 6 2
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 4 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 2 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 3 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 9 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 6 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 7 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 9 2
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 6 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 6 3
7-dehydrocholesterol reductase inhibitor 2-[2-(4-chlorophenyl)... 2 3
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 8 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 7 0
Histamine H3 receptor and Sodium-dependent serotonin transport... 6 1
Delta-type opioid receptor and Kappa-type opioid receptor liga... 2 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 1 2
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 4 0
Mu-type opioid receptor and Gastrin/cholecystokinin type B rec... 1 0
Vesicular acetylcholine transporter inhibitor (2R,3R)-5-(3-flu... 2 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 1 0
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 1 0
Kappa-type opioid receptor and Delta-type opioid receptor liga... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00304901 CHEMBL2338751 Bioactive CHEMBL2338751
CFAMM00304892 CHEMBL2110199 Bioactive CHEMBL2110199
CFAMM00304900 CHEMBL2338750 Bioactive CHEMBL2338750
CFAMM00304891 CHEMBL3038189 Bioactive CHEMBL3038189
CFAMM00304898 CHEMBL2113671 Bioactive CHEMBL2113671
CFAMM00304888 CHEMBL2310915 Bioactive CHEMBL2310915
CFAMM00304897 CHEMBL2338749 Bioactive CHEMBL2338749
CFAMM00304896 CHEMBL2338734 Bioactive CHEMBL2338734
CFAMM00304895 CHEMBL2338733 Bioactive CHEMBL2338733
CFAMM00304902 CHEMBL169367 Bioactive CHEMBL169367
CFAMM00304894 CHEMBL3038197 Bioactive CHEMBL3038197

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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