CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID4244
Family Name Squalene synthase Inhibitor Zwitterionic Sulfobetaine Derivative Family
No. of Seeds 2 No. of Other Members 20
Family Centroid CFAMM00304947 Functional Category Investigative Drug
Superfamily Muscarinic acetylcholine receptor M3 Ligand Diphemanil Methylsulfate Superfamily
Class Class 578

Cousin Family NamesSeedsMembers
5-hydroxytryptamine 2 receptor Ligand tricyclic antidepressant... 29 680
Voltage-dependent T-type calcium channel subunit alpha-1H liga... 10 397
Histamine H1 receptor ligand piperazine derivative Cyclizine F... 16 140
Amine oxidase [flavin-containing] B Inhibitor Selegiline Family 6 26
Muscarinic acetylcholine receptor M3 Ligand Diphemanil Methyls... 22 45
Renin Inhibitor N-methyl-n-(methylbenzyl)formamide Family 2 17
5-hydroxytryptamine receptor 7 and D(2) dopamine receptor Liga... 3 29
D(2) dopamine receptor and D(3) dopamine receptor Ligand (-)-3... 15 19
Potassium voltage-gated channel subfamily H member 2 Ligand 4-... 4 26
Histamine H3 receptor Ligand 1-[2-(2,4,6-trimethyl-phenyl)-eth... 9 15
Sodium-dependent dopamine transporter and Sodium-dependent nor... 28 71
Oxytocin receptor and Vasopressin V1a receptor Ligand 1'-tosyl... 1 7
Sodium-dependent dopamine transporter and Sodium-dependent ser... 8 2
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 1 2
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 3 34
5-hydroxytryptamine receptor 2A and Potassium voltage-gated ch... 2 11
C-C chemokine receptor type 5 ligand methyl N-[1-[(3S)-4-[benz... 3 18
Histamine H3 receptor ligand 2-[4-[4-[2-[(2R)-2-methylpyrrolid... 4 11
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 10
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 1 1
Sigma non-opioid intracellular receptor 1 ligand 1-benzyl-4-[(... 3 2
Sigma non-opioid intracellular receptor 1 ligand 4-benzyl-1-[(... 1 0
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 6 7
C-C chemokine receptor type 5 ligand AC1L9YN4 family 2 33
C-C chemokine receptor type 5 ligand 1-[[(3S,4S)-1-(cyclohexyl... 1 0
Histamine H3 receptor ligand N,N-diethyl-4-[4-[2-[(2R)-2-methy... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00304959 CHEMBL2391072 Bioactive 4-benzyl-1-[(3-methylphenyl)methylsulfonyl]piperidine
CFAMM00304941 CHEMBL2391068 Bioactive 4-benzyl-1-benzylsulfonylpiperidine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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