CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID4264
Family Name Trypsin Inhibitor P1 Argininal Derivative Family
No. of Seeds 13 No. of Other Members 36
Family Centroid CFAMM00305600 Functional Category Bioactive with Natural Product
Superfamily Trypsin Inhibitor P1 Argininal Derivative Superfamily
Class Class 3050

Cousin Family NamesSeedsMembers
Melanocortin receptor 4 Ligand Ro-27-3225 Family 6 52
Integrin alpha-V and Integrin beta-3 Inhibitor C[rgd-(s)-alpha... 19 95
Prothrombin Inhibitor Efegatran Family 9 47
Cathepsin B and Cathepsin S Inhibitor Ac-hphe-leu-ala-leuvsme ... 17 51
Chymase Inhibitor Chymostatin Family 2 3
Substance-P receptor Ligand [sar9,met(o2)11]-sp Family 34 9
Mu-type opioid receptor and Nociceptin receptor Ligand Nocicep... 35 5
Trypsin Inhibitor CVS-2139 Family 2 7
Melanocortin receptor 4 and Melanocyte-stimulating hormone rec... 3 10
Trypsin Inhibitor P1 Argininal Derivative Family 2 8 7
Prothrombin and Suppressor of tumorigenicity 14 protein inhibi... 5 8
Prothrombin inhibitor SureCN7341151 family 6 7
Prothrombin inhibitor (2S)-N-[4-(2-amino-2-iminoethyl)cyclohex... 2 0
Coagulation factor X and Trypsin-1 inhibitor 3-[[(2R)-1-[[2-[[... 1 0
Coagulation factor X inhibitor (6S,8aS)-N-[(1-carbamimidoylpip... 6 0
Prothrombin inhibitor ethyl (3S)-3-(benzylsulfonylamino)-1-[2-... 3 1
Prothrombin inhibitor N-[[(5R,6R)-2-amino-6-methyl-1,4,5,6-tet... 3 2
Prothrombin and Trypsin-1 inhibitor 2-[3-(benzylsulfonylamino)... 4 3
Coagulation factor X inhibitor ethyl 2-[[(3S)-3-[[2-[[(2R)-2-(... 4 0
Prothrombin inhibitor 2-[(3R)-3-amino-3-benzyl-2-oxopiperidin-... 3 0
Genome polyprotein inhibitor Benzoyl-KKR-H family 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00305615 CHEMBL344204 Bioactive 2-[(3S)-3-(benzylsulfonylamino)-2-oxoazepan-1-yl]-N-[(2S)-5-(diaminomethylideneamino)-1-oxopentan-2-yl]acetamide
CFAMM00305621 CHEMBL82032 Bioactive 2-[(3S)-3-(benzylsulfonylamino)-2-oxoazepan-1-yl]-N-[(3S)-1-carbamimidoyl-2-hydroxypiperidin-3-yl]acetamide
CFAMM00305634 CHEMBL162399 Bioactive (2R)-2-(benzylsulfonylamino)-N-[2-[[(3S)-1-carbamimidoyl-2-hydroxypiperidin-3-yl]amino]-2-oxoethyl]-3-(1-carbamimidoylpiperidin-4-yl)propanamide;2,2,2-trifluoroacetic acid
CFAMM00305599 CHEMBL163251 Bioactive 2-(benzylsulfonylamino)-N-[2-[[(3S)-1-carbamimidoyl-2-hydroxypiperidin-3-yl]amino]-2-oxoethyl]-2-(1-carbamimidoylpiperidin-4-yl)acetamide;2,2,2-trifluoroacetic acid
CFAMM00305632 CHEMBL170457 Bioactive 2-[3-(benzylsulfonylamino)-2-oxopiperidin-1-yl]-N-[(3S)-1-carbamimidoyl-2-hydroxypiperidin-3-yl]acetamide
CFAMM00305631 CHEMBL423823 Bioactive (2R)-2-(benzylsulfonylamino)-N-[2-[[(3S)-1-carbamimidoyl-2-hydroxypiperidin-3-yl]amino]-2-oxoethyl]-5-(diaminomethylideneamino)pentanamide;2,2,2-trifluoroacetic acid
CFAMM00305617 CHEMBL162443 Bioactive (2R)-2-(benzylsulfonylamino)-N-[2-[[(3S)-1-carbamimidoyl-2-hydroxypiperidin-3-yl]amino]-2-oxoethyl]-3-(1-carbamimidoylpiperidin-3-yl)propanamide;2,2,2-trifluoroacetic acid
CFAMM00305609 CHEMBL117672 Bioactive 2-(benzylsulfonylamino)-N-[2-[[(3S)-1-carbamimidoyl-2-hydroxypiperidin-3-yl]amino]-2-oxoethyl]-5-(diaminomethylideneamino)pentanamide
CFAMM00305623 CHEMBL84575 Bioactive 2-[(3S)-3-(benzylsulfonylamino)-2-oxoazepan-1-yl]-N-[(3S)-1-carbamimidoyl-2-hydroxypiperidin-3-yl]acetamide;2,2,2-trifluoroacetic acid
CFAMM00305636 CHEMBL367004 Bioactive (2R)-N-[(2S)-1-[[(3S)-1-carbamimidoyl-2-hydroxypiperidin-3-yl]amino]-1-oxopropan-2-yl]-3-hydroxy-2-(2-phenylethylsulfonylamino)propanamide;2,2,2-trifluoroacetic acid
CFAMM00305642 CHEMBL38927 Bioactive 2-[(3S)-3-(benzylsulfonylamino)-2-oxopiperidin-1-yl]-N-[(3S)-1-carbamimidoyl-2-hydroxypiperidin-3-yl]acetamide
CFAMM00305635 CHEMBL112931 Bioactive methyl (3S)-3-(benzylsulfonylamino)-4-[2-[[(3S)-1-carbamimidoyl-2-hydroxypiperidin-3-yl]carbamoyl]pyrrolidin-1-yl]-4-oxobutanoate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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