CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID4265
Family Name Trypsin Inhibitor Benzamidrazone Analogue Family 2
No. of Seeds 6 No. of Other Members 38
Family Centroid CFAMM00305651 Functional Category Investigative Drug
Superfamily Trypsin and Coagulation factor X Binder Superfamily
Class Class 2115

Cousin Family NamesSeedsMembers
Vitamin K-dependent protein C Inhibitor RPR-120844 Family 3 19
Coagulation factor X Inhibitor Azaphenylalanine Derivative Fam... 1 4
Prothrombin and Anionic trypsin inhibitor 3-[(2R)-3-(4-methyls... 2 1
Prostaglandin E2 receptor EP3 subtype ligand AGN-PC-03XGRM family 3 4
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[4-(ben... 12 20
Coagulation factor X inhibitor AGN-PC-0888PO family 2 0
Vasopressin V1a receptor and Vasopressin V1b receptor ligand (... 2 13
B1 bradykinin receptor ligand 2-[1-(4-methoxyphenyl)sulfonyl-3... 1 2
B1 bradykinin receptor ligand 2-[(2R)-1-(4-methylphenyl)sulfon... 4 9
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R)-2-... 4 6
Plasminogen and Plasma kallikrein inhibitor CHEMBL2016871 family 2 0
B1 bradykinin receptor ligand (3R)-N-[(4R)-7-(ethylaminomethyl... 13 10
Renin inhibitor (3S,5R)-N-[[9-(4-methoxybutyl)xanthen-9-yl]met... 1 0
72 kDa type IV collagenase and Neutrophil collagenase inhibito... 12 20
72 kDa type IV collagenase and Collagenase 3 inhibitor 2-[(3Z)... 4 3
72 kDa type IV collagenase and Collagenase 3 inhibitor SureCN7... 5 2
Coagulation factor X and Prothrombin inhibitor Sulfonamidopyrr... 3 0
Prothrombin inhibitor 2-[4-[(4,6-dimethoxynaphthalen-2-yl)sulf... 3 16


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00305660 CHEMBL460378 Bioactive AGN-PC-04XEQQ
CFAMM00305665 CHEMBL424052 Bioactive (2S)-3-[4-(aminomethyl)phenyl]-N-cyclopentyl-2-[(6-methoxynaphthalen-2-yl)sulfonylamino]-N-methylpropanamide
CFAMM00305644 CHEMBL118494 Bioactive 3-[[(3R)-3-[(7-methoxynaphthalen-2-yl)sulfonylamino]-2-oxopyrrolidin-1-yl]methyl]benzenecarboximidamide
CFAMM00305671 CHEMBL334257 Bioactive 3-[4-(aminomethyl)phenyl]-N-cyclopentyl-2-[(6-methoxynaphthalen-2-yl)sulfonylamino]-N-methylpropanamide
CFAMM00305663 CHEMBL312244 Bioactive (2S)-3-[4-[(Z)-C-aminocarbonohydrazonoyl]phenyl]-N-cyclopentyl-2-[(6-methoxynaphthalen-2-yl)sulfonylamino]-N-methylpropanamide
CFAMM00305656 CHEMBL79304 Bioactive (2S)-3-[4-[(Z)-C-aminocarbonohydrazonoyl]-2-fluorophenyl]-N-cyclopentyl-2-[(6-methoxynaphthalen-2-yl)sulfonylamino]-N-methylpropanamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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