CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID430
Family Name Vasopressin-neurophysin 2-copeptin Inhibitor Niravoline Family
No. of Seeds 7 No. of Other Members 45
Family Centroid CFAMM00191067 Functional Category Investigative Drug
Superfamily Vasopressin-neurophysin 2-copeptin Inhibitor Niravoline Superfamily
Class Class 1597

Cousin Family NamesSeedsMembers
D(2) dopamine receptor and D(3) dopamine receptor ligand indol... 4 123
Mu-type opioid receptor Ligand Fentanyl Family 9 647
Nitric oxide synthase, brain Inhibitor NXN-188 Family 1 7
Motilin receptor Ligand GSK962040 Family 30 457
Kappa-type opioid receptor Ligand Asimadoline Family 14 54
K-604 family 4 71
Serine/threonine-protein kinase mTOR Inhibitor CC-223 Family 12 135
Pan-DAC Inhibitor AR-42 Family 21 153
Dual specificity mitogen-activated protein kinase kinase Inhib... 7 69
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand OP... 12 94
5-hydroxytryptamine receptor 1A and Alpha-1A adrenergic recept... 19 88
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 19 32
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 1-methyl-5-(... 6 17
Aromatase Inhibitor 3-(4-amino-phenyl)-1-methyl-pyrrolidine-2,... 4 8
Cannabinoid receptor 1 Ligand 1,3,5-triphenylimidazolidine-2,4... 2 17
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 3 26
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Histamine H3 receptor Ligand (r)-1-(4-nitrophenethyl)-2-methyl... 16 38
Cannabinoid receptor 2 Ligand N1-(4-bromophenyl)-n2,n2-dipenty... 4 21
5-hydroxytryptamine receptor 7 Ligand UCM-5600 Family 15 46
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-(... 2 17
Mitogen-activated protein kinase 14 Inhibitor Dihydro-quinolin... 3 14
Sodium-dependent dopamine transporter and Sodium-dependent nor... 2 7
5-hydroxytryptamine receptor 2A Ligand N-(1-(4-nitrobenzyl)pip... 4 6
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
D(4) dopamine receptor ligand AGN-PC-074VC9 family 2 3
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 2 1
Acetylcholinesterase inhibitor 2-[2-(1-benzylpiperidin-4-yl)et... 2 9
Thyroid hormone receptor beta and DNA-(apurinic or apyrimidini... 1 0
Sigma non-opioid intracellular receptor 1 ligand 2-(2-nitrophe... 2 5
C-C chemokine receptor type 5 ligand N-[1-[(3R)-4-[benzenesulf... 3 2
Kappa-type opioid receptor ligand N-methyl-N-[(1S)-2-pyrrolidi... 3 17
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 2 0
Baculoviral IAP repeat-containing protein 2 and E3 ubiquitin-p... 2 1
Nociceptin receptor and Mu-type opioid receptor ligand N,N-dim... 5 4
Sigma non-opioid intracellular receptor 1 ligand 1-[(3-nitroph... 4 2
Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-(5-nitro-2,3-dihyd... 2 6
Mu-type opioid receptor ligand CHEMBL2310836 family 4 4
Cannabinoid receptor 2 ligand 1-adamantyl-(5-fluoro-2,3-dihydr... 4 7
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 4 6
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 1
5-hydroxytryptamine receptor 7 ligand 3-ethyl-3-[4-[4-(4-fluor... 3 1
Kappa-type opioid receptor ligand 1-[4-acetyl-2-[[(3S)-3-hydro... 1 0
Vascular endothelial growth factor receptor 2 ligand SureCN578... 1 2
D(1A) dopamine receptor and D(3) dopamine receptor ligand 1-[4... 1 0
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 1 0
Kappa-type opioid receptor ligand N-[(2S)-1-(2,5-dihydropyrrol... 1 1
Kappa-type opioid receptor ligand 2-[2-[bis(methylsulfonyl)ami... 2 0
Kappa-type opioid receptor and Delta-type opioid receptor liga... 3 1
Histone deacetylase 1 inhibitor AGN-PC-07ZGOT family 2 1
Substance-P receptor ligand 3-[bis(4-fluorophenyl)methyl]-1-[(... 1 0
Interstitial collagenase and Matrix metalloproteinase-9 inhibi... 2 2
Beta-lactamase inhibitor CHEMBL1406823 family 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00191073 CHEMBL87207 Bioactive SureCN5629262
CFAMM00191100 CHEMBL365198 Bioactive N-methyl-N-[(1S)-1-(3-nitrophenyl)-2-pyrrolidin-1-ylethyl]-2-[4-(trifluoromethyl)phenyl]acetamide
CFAMM00191107 CHEMBL87986 Bioactive SureCN5630038
CFAMM00191054 CHEMBL293619 Bioactive AGN-PC-074BZF
CFAMM00191076 CHEMBL82919 Bioactive SureCN5631204
CFAMM00191112 CHEMBL148377 Bioactive 2-(3-nitrophenyl)-1-[4-(3-phenylpropyl)piperazin-1-yl]ethanone
CFAMM00191067 DNC001021 Investigative Drug Niravoline

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27639 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543