CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID440
Family Name Vasopressin V1a receptor and Vasopressin V2 receptor Ligand OPC-31260 Family
No. of Seeds 12 No. of Other Members 94
Family Centroid CFAMM00191417 Functional Category Investigative Drug with Natural Product
Superfamily Vasopressin V2 receptor and Vasopressin V1a receptor Binder Superfamily
Class Class 1365

Cousin Family NamesSeedsMembers
5-alpha reductase inhibitor azasteroid derivative Dutasteride ... 36 124
D(2) dopamine receptor and D(3) dopamine receptor ligand indol... 4 123
Mu-type opioid receptor Ligand Fentanyl Family 9 647
5-hydroxytryptamine receptor 3A Ligand Palonosetron Family 12 403
Alpha adrenergic receptor Ligand Droperidol Family 20 244
Sodium channel protein type 5 subunit alpha Ligand Procainamid... 7 291
Tumor necrosis factor Inhibitor Thalidomide Family 3 50
D(2) dopamine receptor ligand diphenylbutylpiperidine derivati... 43 161
Histone deacetylase 1 Inhibitor Vorinostat Family 26 138
Serum albumin Inhibitor Ebselen Family 3 62
5-hydroxytryptamine 2 receptor Ligand Ketanserin Family 10 253
Vasopressin V2 receptor Ligand Tolvaptan Family 1 4
Androgen receptor Ligand Enzalutamide Family 1 4
Microsomal triglyceride transfer protein large subunit Inhibit... 15 208
Motilin receptor Ligand GSK962040 Family 30 457
Kappa-type opioid receptor Ligand Asimadoline Family 14 54
Histone deacetylase 1 Inhibitor AN-9 Family 31 282
Dual specificity mitogen-activated protein kinase kinase Inhib... 8 4
K-604 family 4 71
Serine/threonine-protein kinase mTOR Inhibitor CC-223 Family 12 135
Pan-DAC Inhibitor AR-42 Family 21 153
Amonafide family 3 35
Bavisant family 9 65
Dual specificity mitogen-activated protein kinase kinase Inhib... 7 69
5-hydroxytryptamine receptor 2A Ligand N-(1-(1-phenylethyl)pip... 22 207
Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
Delta-type opioid receptor Ligand Sb 227122 Family 7 5
C-C chemokine receptor type 5 Ligand Tak-220 Family 8 56
Integrin alpha-4 Inhibitor BIO-1211 Family 16 83
Hemagglutinin Inhibitor Cl 385319 Family 18 101
Vasopressin V2 receptor Ligand FR161282 Family 17 83
Farnesyltransferase beta subunit, putative and Protein farnesy... 6 18
Poly(ADP-ribose) glycohydrolase Inhibitor N-bis-(3-phenyl-prop... 3 7
Vasopressin-neurophysin 2-copeptin Inhibitor Niravoline Family 7 45
5-hydroxytryptamine receptor 4 Ligand TD-5108 Family 21 24
Vasopressin V2 receptor Ligand VP-343 Family 1 0
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-m... 8 37
Fumarate reductase flavoprotein subunit Inhibitor 2-heptyl-4-h... 3 16
Urokinase-type plasminogen activator Inhibitor 6-(n-phenylcarb... 2 11
Liver carboxylesterase 1 Inhibitor 1-methyl-1h-indole-2,3-dion... 10 35
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor N-(4-s... 12 92
Beta-secretase 1 Inhibitor N-(1-benzylpiperidin-4-yl)-4-sulfan... 7 62
Epidermal growth factor receptor Ligand 5,6-bis-p-tolylamino-i... 2 2
Potassium voltage-gated channel subfamily A member 5 Ligand N-... 8 32
Integrin beta-3 Inhibitor L-767679 Family 3 6
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 1-methyl-5-(... 6 17
Integrin beta-3 Inhibitor L-750034 Family 7 38
Integrin beta-3 Inhibitor SB-208651 Family 9 28
Integrin beta-3 Inhibitor Lotrafiban Family 5 1
Aromatase Inhibitor 3-(4-amino-phenyl)-1-methyl-pyrrolidine-2,... 4 8
Acetyl-CoA acetyltransferase, mitochondrial Inhibitor Octanoic... 4 14
Fatty acid-binding protein and C-X-C chemokine receptor type 1... 1 6
Poly [ADP-ribose] polymerase 1 Inhibitor 8-amino-6h,11h-indeno... 3 9
Transient receptor potential cation channel subfamily V member... 6 33
Poly [ADP-ribose] polymerase 1 Inhibitor 3-morpholin-4-ylmethy... 1 2
Cathepsin K and Cathepsin L1 Inhibitor N-benzoyl-phenylalanyl-... 13 77
Cannabinoid receptor 1 Ligand 1,3,5-triphenylimidazolidine-2,4... 2 17
Sodium-dependent dopamine transporter and Sodium-dependent nor... 2 13
Acetylcholinesterase Inhibitor Bw-28c51 Family 3 8
Cholecystokinin receptor type A Ligand VL-1499 Family 12 133
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 41 24
Aurora kinase B Inhibitor Hesperadin Family 1 1
Integrin alpha-2 and Integrin beta-3 Inhibitor 3-(3-(carbamoyl... 7 13
Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 7 35
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 3 26
Beta-secretase 1 and Cathepsin D Inhibitor GRL-7234 Family 17 148
Kinesin-like protein KIF11 Inhibitor N-[4'-(trifluoromethyl)-4... 7 134
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 7 13
Telomerase reverse transcriptase Inhibitor 2,7-dinitroantraqui... 3 8
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Oxysterols receptor LXR-alpha Ligand 2-(2-phenethylphenyl)isoi... 4 7
Transient receptor potential cation channel subfamily V member... 1 5
Progesterone receptor Ligand 3-(3,3-dimethyl-2-oxoindolin-5-yl... 2 10
Leukotriene A-4 hydrolase Inhibitor N5-[4-benzylphenyl]-l-glut... 2 1
Cannabinoid receptor 2 Ligand N1-(4-bromophenyl)-n2,n2-dipenty... 4 21
Phospholipase D1 Inhibitor Halopemide Family 17 111
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 1 1
5-hydroxytryptamine receptor 7 Ligand UCM-5600 Family 15 46
Telomerase reverse transcriptase Inhibitor 2,7-bis[2-(piperidi... 6 8
Poly [ADP-ribose] polymerase 1 Inhibitor 5-aminoisoquinolin-1(... 2 8
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 4 12
Vasopressin V2 receptor Ligand VA-106483 Family 16 115
Muscarinic acetylcholine receptor M4 and Muscarinic acetylchol... 20 55
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-(... 2 17
Metabotropic glutamate receptor 5 Ligand N-(3-acetamidophenyl)... 4 20
Mitogen-activated protein kinase 14 Inhibitor Dihydro-quinolin... 3 14
Sodium-dependent dopamine transporter and Sodium-dependent nor... 2 7
Sodium-dependent dopamine transporter and Sodium-dependent nor... 19 28
Histone deacetylase 2 Inhibitor N-(4-amino-4'-bromobiphenyl-3-... 1 1
MO15-related protein kinase Pfmrk Inhibitor 2-chloro-n-(o-toly... 6 28
Bifunctional epoxide hydrolase 2 Inhibitor 1-phenyl-3-(1-propi... 22 183
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 1 14
Arachidonate 5-lipoxygenase and Prostaglandin G/H synthase 1 I... 9 7
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 12 4
D(2) dopamine receptor Ligand PD-168077 Family 6 5
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand 9h-bet... 1 1
Aldose reductase Inhibitor (4-methyl-2-oxo-2h-quinolin-1-yl)-a... 1 15
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 15 129
5-hydroxytryptamine receptor 2A Ligand N-(1-(4-nitrobenzyl)pip... 4 6
5-hydroxytryptamine receptor 2A Ligand N-(1-(3-bromobenzyl)pip... 6 10
Voltage-dependent calcium channel gamma-1 subunit Ligand NP-11... 8 9
Metabotropic glutamate receptor 5 Ligand 3-cyano-n-(3-cyanophe... 7 5
Cholecystokinin receptor type A Ligand VL-0494 Family 1 0
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
Prothrombin and Plasminogen inhibitor [(1R)-5-amino-1-[[2-[N-(... 1 0
D(4) dopamine receptor ligand AGN-PC-074VC9 family 2 3
Vasopressin V2 receptor and Vasopressin V1a receptor ligand N-... 5 8
Vasopressin V1a receptor and Vasopressin V2 receptor ligand CH... 3 5
Vasopressin V1a receptor ligand AGN-PC-074VJP family 3 1
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 4 10
Substance-P receptor ligand (2S)-2-N-[(2S)-1-[benzyl(methyl)am... 6 3
Rho-associated protein kinase 2 inhibitor N-(7-chloro-1-oxo-2H... 13 42
Acetylcholinesterase inhibitor AGN-PC-07ZFTY family 1 0
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-04UEDE family 7 17
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-07ZFJZ family 1 3
Substance-K receptor and Substance-P receptor ligand N-[4-[[4-... 1 4
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 1 0
Vasopressin V1a receptor ligand AGN-PC-074VSA family 3 0
3-oxo-5-alpha-steroid 4-dehydrogenase 2 and 3-oxo-5-alpha-ster... 4 8
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 15 24
72 kDa type IV collagenase and Stromelysin-1 inhibitor [(2S)-2... 9 6
Progesterone receptor and Androgen receptor ligand AGN-PC-080P... 4 27
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand N-(1-... 5 13
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 1-eth... 7 3
Cathepsin K and Cathepsin B inhibitor AGN-PC-01Z23J family 2 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 7 5
C-C chemokine receptor type 3 ligand 4-[(3-acetylphenyl)carbam... 3 4
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 1 4
Melanocortin receptor 4 and Melanocortin receptor 5 ligand N-[... 16 117
Lethal factor inhibitor (2R)-2-(4-fluoro-3,5-dimethylanilino)-... 11 8
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(2S)-1... 6 6
Integrin beta-3 and Integrin alpha-IIb inhibitor SureCN7345980... 4 6
C-C chemokine receptor type 3 ligand SureCN6703027 family 2 1
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 5
Acetylcholinesterase inhibitor CHEMBL1651130 family 2 3
Vasopressin V2 receptor ligand [2-chloro-4-(prop-2-enylamino)p... 3 14
Apolipoprotein B-100 and Microsomal triglyceride transfer prot... 7 1
Apolipoprotein B-100 and Microsomal triglyceride transfer prot... 10 0
Cellular tumor antigen p53 and Beta-lactamase inhibitor CHEMBL... 1 53
Acetylcholinesterase inhibitor 2-[2-(1-benzylpiperidin-4-yl)et... 2 9
Apolipoprotein B-100 and Microsomal triglyceride transfer prot... 3 0
Apolipoprotein B-100 and Microsomal triglyceride transfer prot... 6 5
Sigma non-opioid intracellular receptor 1 ligand 2-(2-nitrophe... 2 5
Hypoxia-inducible factor 1-alpha and Ubiquitin carboxyl-termin... 1 1
Mitogen-activated protein kinase 13 and Mitogen-activated prot... 2 4
Mitogen-activated protein kinase 13 and Mitogen-activated prot... 4 3
72 kDa type IV collagenase and Stromelysin-1 inhibitor (2R)-N-... 2 7
D(3) dopamine receptor and Alpha-1B adrenergic receptor ligand... 11 8
Calcitonin gene-related peptide type 1 receptor and Dual speci... 8 4
Prelamin-A/C inhibitor CHEMBL1547148 family 1 8
Substance-P receptor ligand (2S,4S)-2-N-[3-(diethylamino)propy... 2 7
Cellular tumor antigen p53 and Inositol monophosphatase 1 inhi... 1 12
Cellular tumor antigen p53 inhibitor CHEMBL1554992 family 1 0
Peptide deformylase inhibitor (2R)-2-[[formyl(hydroxy)amino]me... 2 1
Peptide deformylase inhibitor (2R)-2-(cyclopentylmethyl)-3-[fo... 11 2
Prelamin-A/C and Lysine-specific demethylase 4E inhibitor 4-(4... 2 3
Vasopressin V2 receptor and Vasopressin V1a receptor ligand AG... 4 19
D(2) dopamine receptor and D(3) dopamine receptor ligand 1,1-d... 2 7
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[(1-benz... 5 2
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor lig... 8 1
Cannabinoid receptor 2 ligand AGN-PC-087MPO family 7 21
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 1 0
Amyloid beta A4 protein inhibitor AGN-PC-08WTQK family 1 3
Stromelysin-1 and 72 kDa type IV collagenase inhibitor (2R)-2-... 2 1
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 4 0
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[(E... 24 11
Vasopressin V2 receptor and Vasopressin V1a receptor ligand 2-... 6 9
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 6
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 2 3
Androgen receptor ligand SureCN13483375 family 3 2
Histone deacetylase and Histone deacetylase 3 inhibitor (3S,6S... 2 4
Melanin-concentrating hormone receptor 1 ligand AGN-PC-075BLN ... 2 1
Mitogen-activated protein kinase 14 inhibitor N-cyclopropyl-4-... 4 0
Ectonucleotide pyrophosphatase/phosphodiesterase family member... 1 1
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand N-(1-... 1 0
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 8 1
Melanocortin receptor 4 ligand (3R)-N-[(2R)-3-(4-chlorophenyl)... 6 9
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A ... 2 2
Kappa-type opioid receptor ligand N-methyl-N-[(1S)-2-pyrrolidi... 3 17
D(4) dopamine receptor ligand 1-Piperidineacetamide, 4-(2-cyan... 3 7
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 3 5
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 2 0
Follicle-stimulating hormone receptor ligand AGN-PC-005HER family 5 2
5-hydroxytryptamine receptor 1A ligand SureCN4244417 family 10 1
C-C chemokine receptor type 3 and Sodium-dependent serotonin t... 12 2
Delta-type opioid receptor and Potassium voltage-gated channel... 3 2
Transient receptor potential cation channel subfamily V member... 9 38
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 1 0
Neuronal acetylcholine receptor subunit alpha-7 ligand 2,7-bis... 2 1
Neuronal acetylcholine receptor subunit alpha-7 ligand 2,7-bis... 3 2
Histamine H3 receptor ligand SureCN3058680 family 4 0
Baculoviral IAP repeat-containing protein 2 and E3 ubiquitin-p... 2 1
Transient receptor potential cation channel subfamily V member... 1 1
Oxytocin receptor ligand (2R)-2-[(2R,5R)-5-(2,3-dihydro-1H-ind... 2 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 3 0
Kappa-type opioid receptor and Cytochrome P450 2D6 ligand Sure... 11 9
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 5 19
Testosterone 17-beta-dehydrogenase 3 inhibitor SureCN4802053 f... 2 2
Bifunctional epoxide hydrolase 2 inhibitor 1-(3-acetylphenyl)-... 1 3
Sphingosine 1-phosphate receptor 1 ligand 7-(2-hydroxyethyl)-1... 2 10
Substance-P receptor and Potassium voltage-gated channel subfa... 5 0
Histone deacetylase 1 and Histone deacetylase 6 inhibitor (2E)... 2 1
D(2) dopamine receptor and Potassium voltage-gated channel sub... 1 1
Nociceptin receptor and Mu-type opioid receptor ligand N,N-dim... 5 4
Microsomal triglyceride transfer protein large subunit inhibit... 8 1
Substance-P receptor and Substance-K receptor ligand AGN-PC-07... 5 2
Melanin-concentrating hormone receptor 1 ligand AGN-PC-0762XZ ... 3 1
Cathepsin K and Cathepsin B inhibitor (1R,2R)-N-(cyanomethyl)-... 1 6
ALK tyrosine kinase receptor ligand 4-fluoro-N-[6-(piperidin-1... 10 7
Mitogen-activated protein kinase 14 inhibitor N-[3-[(11-oxo-5,... 2 0
C-C chemokine receptor type 3 ligand 1-(3-acetylphenyl)-3-[3-[... 9 1
P2X purinoceptor 7 inhibitor AGN-PC-050YNC family 1 6
Mitogen-activated protein kinase 14 inhibitor ethyl 2-[[3-(2,4... 4 0
Mitogen-activated protein kinase 14 inhibitor 3-(3-benzamido-4... 2 0
Mitogen-activated protein kinase 14 inhibitor 3-(2,4-difluoroa... 6 0
P2X purinoceptor 7 inhibitor 2-[3-fluoro-4-(trifluoromethyl)ph... 3 0
Cannabinoid receptor 2 ligand 1-adamantyl-(5-fluoro-2,3-dihydr... 4 7
Cannabinoid receptor 2 ligand AGN-PC-046LZ0 family 1 0
Histone deacetylase 1 inhibitor SureCN3642893 family 10 23
Melanocortin receptor 4 ligand N-[(1S)-1-[2-[4-[(3S,4R)-4-(4-c... 26 13
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 4 6
C-C chemokine receptor type 1 ligand 3-[2-(carbamoylamino)phen... 2 1
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 2 1
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 1
Melanin-concentrating hormone receptor 1 ligand SureCN5517533 ... 2 3
Histamine receptor H3 ligand N-[2-methyl-4-[(3S)-3-[(2S)-2-met... 10 7
C-C chemokine receptor type 2 ligand 2-amino-N-[2-[[(3R)-1-[(4... 5 1
Vasopressin V1a receptor and Vasopressin V2 receptor ligand Su... 1 1
Somatostatin receptor type 1 and Somatostatin receptor type 2 ... 2 11
C-C chemokine receptor type 2 ligand 2-amino-N-[2-[[(3R)-1-[(3... 2 4
Coagulation factor X inhibitor N-(4-chlorophenyl)-2-[[4-(2-oxo... 2 0
5-hydroxytryptamine receptor 7 ligand 3-ethyl-3-[4-[4-(4-fluor... 3 1
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 1 0
C-C chemokine receptor type 2 ligand 2-amino-N-[2-[[(3R)-1-[(4... 1 1
5-hydroxytryptamine receptor 7 ligand 2-[4-[4-(2-oxo-1,3,4,5-t... 1 0
Growth hormone secretagogue receptor type 1 ligand 2-amino-2-m... 4 2
Chitin synthase 1 inhibitor AC1O53V7 family 9 0
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 7 12
Substance-P receptor ligand N-[[3,5-bis(trifluoromethyl)phenyl... 1 0
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 3 2
Growth hormone secretagogue receptor type 1 ligand SureCN77944... 1 2
C-C chemokine receptor type 5 and Potassium voltage-gated chan... 4 0
D(3) dopamine receptor and D(2) dopamine receptor ligand 2-[5-... 3 0
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 11 4
Vasopressin V2 receptor and Vasopressin V1a receptor ligand AG... 5 1
Vasopressin V2 receptor and Vasopressin V1a receptor ligand 2-... 4 0
Protease and Replicase polyprotein 1a inhibitor AC1LALLS family 1 0
C-C chemokine receptor type 3 ligand AGN-PC-075BAT family 1 0
Sodium-dependent noradrenaline transporter inhibitor AGN-PC-07... 1 1
Microsomal triglyceride transfer protein large subunit inhibit... 2 0
Vascular endothelial growth factor receptor 2 ligand isoindoli... 1 0
Transient receptor potential cation channel subfamily V member... 1 1
Histone deacetylase 6 and Histone deacetylase 2 inhibitor 4-[[... 2 1
Phospholipase D1 and Phospholipase D2 inhibitor N-[(2S)-1-[4-(... 4 0
Phospholipase D1 and Phospholipase D2 inhibitor N-[(2S)-1-[4-(... 3 5
72 kDa type IV collagenase and Disintegrin and metalloproteina... 1 5
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand N-(1-... 1 2
Vascular endothelial growth factor receptor 2 ligand SureCN578... 1 2
Muscarinic acetylcholine receptor M2 ligand AGN-PC-073RRB family 2 1
Collagenase 3 and Interstitial collagenase inhibitor (2R,3S)-N... 1 0
Mitogen-activated protein kinase 14 and Serine/threonine-prote... 1 1
Neuropeptide Y receptor type 5 ligand AGN-PC-01NRZK family 3 0
Acetylcholinesterase inhibitor tmtfa family 1 2
Integrin beta-3 and Integrin alpha-IIb inhibitor AGN-PC-009EMK... 2 1
5-hydroxytryptamine receptor 4 ligand 2-oxo-N-[(1R,5S)-8-(2-pi... 13 5
D(1A) dopamine receptor and D(3) dopamine receptor ligand 1-[4... 1 0
P2X purinoceptor 7 inhibitor 2-(1-adamantyl)-N-[2-(1-hydroxy-3... 3 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 3 2
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 3 3
C-C chemokine receptor type 5 ligand AC1MHPA7 family 2 2
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 3
Vasopressin V2 receptor and Vasopressin V1a receptor ligand (2... 4 0
C-C chemokine receptor type 5 ligand AC1MHP8Y family 1 0
Kappa-type opioid receptor and Delta-type opioid receptor liga... 3 1
Beta-lactamase inhibitor (1R,5S)-4-[(4-carbamoylphenyl)carbamo... 3 2
Tyrosine-protein kinase ITK/TSK and Mast/stem cell growth fact... 1 0
Glucose-dependent insulinotropic receptor ligand AGN-PC-04UO8L... 2 2
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 1 1
C-X-C chemokine receptor type 3 ligand AGN-PC-00PW0E family 3 11
Caspase-3 and Caspase-7 inhibitor AGN-PC-00BUR6 family 2 1
Caspase-3 inhibitor Benzamide, 3-nitro-N-(1,2,3,4-tetrahydro-1... 2 3
Caspase-3 inhibitor SureCN12857739 family 1 1
Cathepsin S and Cathepsin L1 inhibitor arylaminoethyl amide de... 2 4
C-C chemokine receptor type 2 ligand AGN-PC-00D2HV family 2 2
Vasopressin V1a receptor and Vasopressin V2 receptor ligand Su... 3 0
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 1 0
C5a anaphylatoxin chemotactic receptor 1 ligand SureCN12047568... 1 1
Protein farnesyltransferase subunit beta and Protein farnesylt... 4 13
Progesterone receptor ligand AGN-PC-048NI9 family 1 5
Histone deacetylase 6 and Histone deacetylase 1 inhibitor AGN-... 1 2
Serine/threonine-protein kinase Chk1 inhibitor 6-oxo-9-(2-oxo-... 1 0
Multidrug resistance protein 1 inhibitor AGN-PC-07R6HU family 1 0
Transient receptor potential cation channel subfamily A member... 1 0
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 1 1
Proteinase-activated receptor 1 ligand 2-bromo-N-[3-(butanoyla... 4 0
Metabotropic glutamate receptor 2 ligand 4-[4-(methylamino)phe... 1 4
Polymerase acidic protein inhibitor (Z)-4-hydroxy-2-oxo-4-(4-p... 1 0
Lysophosphatidic acid receptor 3 and Microtubule-associated pr... 1 1
Acenes Metabolite C.I. Pigment Red 149 Family 1 0
(8-methyl-6-oxo-1,2,3a,4,5,6-hexahydro-3H-3,10b-diazaacephenan... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00191347 CHEMBL100402 Bioactive AGN-PC-074T7W
CFAMM00191414 CHEMBL544159 Bioactive BBPEP
CFAMM00191405 CHEMBL573775 Bioactive AGN-PC-07COU1
CFAMM00191441 CHEMBL138107 Bioactive 144319-66-4
CFAMM00191438 CHEMBL274125 Bioactive SureCN7455332
CFAMM00191326 DNC005942 Investigative Drug para-sirtinol
CFAMM00191417 DNC001063 Investigative Drug OPC-31260

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27271 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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